Metformin inhibits mTOR-HIF-1α axis and profibrogenic and inflammatory biomarkers in thioacetamide-induced hepatic tissue alterations
出版年份 2018 全文链接
标题
Metformin inhibits mTOR-HIF-1α axis and profibrogenic and inflammatory biomarkers in thioacetamide-induced hepatic tissue alterations
作者
关键词
-
出版物
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-10-18
DOI
10.1002/jcp.27616
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Swim exercise training ameliorates hepatocyte ultrastructural alterations in rats fed on a high fat and sugar diet
- (2018) Mohammed A. Dallak et al. ULTRASTRUCTURAL PATHOLOGY
- Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase
- (2018) Zhen Li et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells
- (2017) Junping Hu et al. Scientific Reports
- TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
- (2017) Nina D. Thiele et al. Scientific Reports
- Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway
- (2016) Yan-Ling Wu et al. TOXICOLOGY LETTERS
- Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells
- (2016) Sacha Robert et al. PLoS One
- mTOR Overactivation in Mesenchymal cells Aggravates CCl4− Induced liver Fibrosis
- (2016) Lanlan Shan et al. Scientific Reports
- Standard Operating Procedures in Experimental Liver Research: Thioacetamide model in mice and rats
- (2015) MC Wallace et al. LABORATORY ANIMALS
- HIF-1α pathway: role, regulation and intervention for cancer therapy
- (2015) Georgina N. Masoud et al. Acta Pharmaceutica Sinica B
- Repurposing of Metformin and Aspirin by Targeting AMPK-mTOR and Inflammation for Pancreatic Cancer Prevention and Treatment
- (2014) W. Yue et al. Cancer Prevention Research
- Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway
- (2014) Yanling Zhao et al. FITOTERAPIA
- Rapamycin Ameliorates Inflammation and Fibrosis in the Early Phase of Cirrhotic Portal Hypertension in Rats through Inhibition of mTORC1 but Not mTORC2
- (2014) Weijie Wang et al. PLoS One
- Hepatic inflammation and progressive liver fibrosis in chronic liver disease
- (2014) Albert J Czaja WORLD JOURNAL OF GASTROENTEROLOGY
- Hypoxia-Inducible Factor 1 Regulation through Cross Talk between mTOR and MT1-MMP
- (2013) T. Sakamoto et al. MOLECULAR AND CELLULAR BIOLOGY
- Curcumin ameliorates intrahepatic angiogenesis and capillarization of the sinusoids in carbon tetrachloride-induced rat liver fibrosis
- (2013) Qunyan Yao et al. TOXICOLOGY LETTERS
- Mini-Special Issue paper Management of diabetic patients with hypoglycemic agents Metformin and its clinical use: new insights for an old drug in clinical practice
- (2012) Arrigo F.G. Cicero et al. Archives of Medical Science
- Effects of simvastatin administration on rodents with lipopolysaccharide-induced liver microvascular dysfunction
- (2012) Vincenzo La Mura et al. HEPATOLOGY
- Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase
- (2012) Hui-Min Xu WORLD JOURNAL OF GASTROENTEROLOGY
- Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia
- (2010) P. Matafome et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Activation of Proteinase-Activated Receptor 2 Stimulates Soluble Vascular Endothelial Growth Factor Receptor 1 Release via Epidermal Growth Factor Receptor Transactivation in Endothelial Cells
- (2010) Bahjat Al-Ani et al. HYPERTENSION
- Differential Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Thioacetamide-Induced Chronic Liver Injury
- (2010) Soo Young Park et al. JOURNAL OF KOREAN MEDICAL SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started