NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells

Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183

(2018) Yan Wu et al.   PLoS One

RNF183 promotes proliferation and metastasis of colorectal cancer cells via activation of NF-κB-IL-8 axis

(2017) Rong Geng et al.   Cell Death & Disease

E3 Ubiquitin ligase RNF183 Is a Novel Regulator in Inflammatory Bowel Disease

(2016) Qiao Yu et al.   Journal of Crohns & Colitis

Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation

(2016) Masayuki Kaneko et al.   Scientific Reports

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

(2015) Jonathan Jantsch et al.   Cell Metabolism

KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and Lysosome-Mediated Degradation

(2015) Jenny H. Hong et al.   MOLECULAR & CELLULAR PROTEOMICS

Comprehensive functional characterization of cancer–testis antigens defines obligate participation in multiple hallmarks of cancer

(2015) Kimberly E. Maxfield et al.   Nature Communications

The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4

(2014) Justine Holleman et al.   MOLECULAR BIOLOGY OF THE CELL

Tissue-specific control of brain-enriched miR-7 biogenesis

(2013) N. R. Choudhury et al.   GENES & DEVELOPMENT

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte development

(2013) R. Berga-Bolanos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

(2012) Maria Buxadé et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The spatial and temporal organization of ubiquitin networks

(2011) Caroline Grabbe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Expression of Aquaporin-1 in the Medulla of the Kidney Is Dependent on the Transcription Factor Associated with Hypertonicity, TonEBP

(2010) Miguel A. Lanaspa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFAT5 Regulates T Lymphocyte Homeostasis and CD24-Dependent T Cell Expansion under Pathologic Hypernatremia

(2010) R. Berga-Bolanos et al.   JOURNAL OF IMMUNOLOGY

Osmoprotective Transcription Factor NFAT5/TonEBP Modulates Nuclear Factor-κB Activity

(2010) Isabelle Roth et al.   MOLECULAR BIOLOGY OF THE CELL

Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents

(2009) Songcang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

(2009) Agnes Machnik et al.   NATURE MEDICINE

NF-κB Modulates Aquaporin-2 Transcription in Renal Collecting Duct Principal Cells

(2008) Udo Hasler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interstitial tonicity controls TonEBP expression in the renal medulla

(2008) Mee R. Sheen et al.   KIDNEY INTERNATIONAL