Overcoming bioethical, legal, and hereditary barriers to mitochondrial replacement therapy in the USA

Uterine Transplant: A Risk to Life or a Chance for Life?

(2018) Alankrita Taneja et al.   SCIENCE AND ENGINEERING ETHICS

Transgenic Chicken, Mice, Cattle, and Pig Embryos by Somatic Cell Nuclear Transfer into Pig Oocytes

(2018) Mukesh Kumar Gupta et al.   Cellular Reprogramming

Mitochondrial Replacement Therapy: Are Mito-nuclear Interactions Likely To Be a Problem?

(2017) Adam Eyre-Walker   GENETICS

Genetic affinity and the right to ‘three-parent IVF’

(2017) G. Owen Schaefer et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Live birth derived from oocyte spindle transfer to prevent mitochondrial disease

(2017) John Zhang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Mitochondrial Replacement Therapy: Are Mito-nuclear Interactions Likely To Be a Problem?

(2017) Adam Eyre-Walker   GENETICS

Long-term Survival, Organ Function, and Malignancy after Hematopoietic Stem Cell Transplantation for Fanconi Anemia

(2016) Carmem Bonfim et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelic polymorphisms and/or consanguinity in Saudi Arabia

(2016) Rola F. Turki et al.   BMC Medical Genetics

First live birth using human oocytes reconstituted by spindle nuclear transfer for mitochondrial DNA mutation causing Leigh syndrome

(2016) J. Zhang et al.   FERTILITY AND STERILITY

Attitudes toward prevention of mtDNA-related diseases through oocyte mitochondrial replacement therapy

(2016) Kristin Engelstad et al.   HUMAN REPRODUCTION

Mitochondrial donation and ‘the right to know’

(2016) Reuven Brandt   JOURNAL OF MEDICAL ETHICS

The Public and the Gene-Editing Revolution

(2016) Robert J. Blendon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial Replacement Techniques — Implications for the Clinical Community

(2016) Marni J. Falk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Social and ethical issues in mitochondrial donation: Fig. 1

(2015) Rebecca Dimond   BRITISH MEDICAL BULLETIN

Mutations causing mitochondrial disease: What is new and what challenges remain?

(2015) R. N. Lightowlers et al.   SCIENCE

Updated: Budget agreement boosts U.S. science

(2015) Jeffrey Mervis   SCIENCE

Mitochondrial replacement therapy in reproductive medicine

(2015) Don P. Wolf et al.   TRENDS IN MOLECULAR MEDICINE

Microchimerism after pancreas and kidney transplantation – a review

(2015) Małgorzata Zagozda et al.   Annals of Transplantation

Three-parent in vitro fertilization: gene replacement for the prevention of inherited mitochondrial diseases

(2014) Paula Amato et al.   FERTILITY AND STERILITY

Preventing the transmission of pathogenic mitochondrial DNA mutations: can we achieve long-term benefits from germ-line gene transfer?

(2013) D. C. Samuels et al.   HUMAN REPRODUCTION

Harnessing the Stem Cell Potential: The path to prevent mitochondrial disease

(2013) Akemi J Tanaka et al.   NATURE MEDICINE

Clinical and ethical implications of mitochondrial gene transfer

(2013) Shoukhrat Mitalipov et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease

(2013) D. C. Wallace et al.   Cold Spring Harbor Perspectives in Biology

Upper-Extremity Transplantation Using a Cell-Based Protocol to Minimize Immunosuppression

(2012) Stefan Schneeberger et al.   ANNALS OF SURGERY

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

(2012) Daniel Paull et al.   NATURE

Towards germline gene therapy of inherited mitochondrial diseases

(2012) Masahito Tachibana et al.   NATURE

Monogenic Mitochondrial Disorders

(2012) Werner J.H. Koopman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapid Mitochondrial DNA Segregation in Primate Preimplantation Embryos Precedes Somatic and Germline Bottleneck

(2012) Hyo-Sang Lee et al.   Cell Reports

Mitochondrial DNA disease: new options for prevention

(2011) L. Craven et al.   HUMAN MOLECULAR GENETICS

Mitochondrial DNA and disease

(2011) Laura C Greaves et al.   JOURNAL OF PATHOLOGY

The spectrum of pyruvate dehydrogenase complex deficiency: Clinical, biochemical and genetic features in 371 patients

(2011) Kavi P. Patel et al.   MOLECULAR GENETICS AND METABOLISM

Mitochondrial DNA mutations and human disease

(2009) Helen A.L. Tuppen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

(2008) Hannah R. Elliott et al.   AMERICAN JOURNAL OF HUMAN GENETICS