Aging-Related Calcium Dysregulation in Rat Entorhinal Neurons Homologous with the Human Entorhinal Neurons in which Alzheimer’s Disease Neurofibrillary Tangles First Appear

FK506-Binding Protein 12.6/1b, a negative regulator of [Ca2+], rescues memory and restores genomic regulation in the hippocampus of aging rats

(2017) John C. Gant et al.   JOURNAL OF NEUROSCIENCE

Pathology of the Aging Brain in Domestic and Laboratory Animals, and Animal Models of Human Neurodegenerative Diseases

(2016) S. A. Youssef et al.   VETERINARY PATHOLOGY

Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus

(2015) J. C. Gant et al.   JOURNAL OF NEUROSCIENCE

Animal Models of Aging Research: Implications for Human Aging and Age-Related Diseases

(2015) Sarah J. Mitchell et al.   Annual Review of Animal Biosciences

Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies

(2014) Cassia R Overk et al.   Molecular Neurodegeneration

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

An analysis of entorhinal cortex projections to the dentate gyrus, hippocampus, and subiculum of the neonatal macaque monkey

(2013) David G. Amaral et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Epidemiology of Alzheimer Disease

(2013) R. Mayeux et al.   Cold Spring Harbor Perspectives in Medicine

Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

(2012) E. Hudry et al.   JOURNAL OF NEUROSCIENCE

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits

(2012) Julie A. Harris et al.   PLoS One

Disrupting Function of FK506-Binding Protein 1b/12.6 Induces the Ca2+-Dysregulation Aging Phenotype in Hippocampal Neurons

(2011) J. C. Gant et al.   JOURNAL OF NEUROSCIENCE

Age-related increase of sIAHP in prefrontal pyramidal cells of monkeys: relationship to cognition

(2010) J.I. Luebke et al.   NEUROBIOLOGY OF AGING

Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice

(2010) Anete Rozkalne et al.   NEUROBIOLOGY OF DISEASE

Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory Impairment

(2009) I. Kadish et al.   JOURNAL OF NEUROSCIENCE

Estradiol Reverses a Calcium-Related Biomarker of Brain Aging in Female Rats

(2009) L. D. Brewer et al.   JOURNAL OF NEUROSCIENCE

Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

(2009) M. Polydoro et al.   JOURNAL OF NEUROSCIENCE

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Gene expression changes in the course of normal brain aging are sexually dimorphic

(2008) N. C. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

More than a decade of estrogen neuroprotection

(2007) James W. Simpkins et al.   Alzheimers & Dementia