4.5 Article

Association between cardiorespiratory fitness, obesity, and health care costs: The Veterans Exercise Testing Study

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INTERNATIONAL JOURNAL OF OBESITY
卷 43, 期 11, 页码 2225-2232

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NATURE PUBLISHING GROUP
DOI: 10.1038/s41366-018-0257-0

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  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)/Programa de Doutorado Sanduiche [88881.136006/2016-01]

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Background/Objective Obesity is a chronic disease, a risk factor for other chronic conditions and for early mortality, and is associated with higher health care utilization. Annual spending among obese individuals is at least 30% higher vs. that for normal-weight peers. In contrast, higher cardiorespiratory fitness (CRF) is related to many health benefits. We sought to examine the association between CRF and health care costs across the spectrum of body mass index (BMI). Methods Data from 3,924 men (58.1 +/- 11.1 years, 29.2 +/- 5.3 kg.m(-2)) who completed a maximal exercise test for clinical reasons and to estimate CRF were recorded prospectively at the time of testing. Cost data (USD) from each subject during a 6-year period after the exercise test were merged with the exercise database and compared according to BMI and estimated CRF (CRFe). Subjects were categorized as normal-weight (BMI < 25.0 kg.m(-2)), overweight (BMI 25.0-29.9 kg.m(-2)), and obese (BMI = 30.0 kg.m(-2)). We also formed four CRFe categories based on age-stratified quartiles of metabolic equivalents (METs) achieved: least-fit (5.1 +/- 1.5 METs; n = 1,044), moderately-fit (7.6 +/- 1.5 METs; n = 938), fit (9.4 +/- 1.5 METs; n = 988), and highly-fit (12.4 +/- 2.2 METs; n = 954). Results Average annual costs per person adjusted for age and presence of cardiovascular disease were $37,018, $40,572, and $45,683 for normal-weight, overweight, and obese subjects, respectively (p < 0.01). For each 1-MET incremental increase in CRFe, annual cost savings per person were $3,272, $4,252, and $6,103 for normal-weight, overweight, and obese subjects, respectively. Stratified by CRFe categories, annual costs for normal-weight, overweight, and obese subjects in the highest CRFe quartile were $28,028, $31,669, and $32,807 lower, respectively, compared to subjects in the lowest CRFe quartile (p < 0.01). Conclusion Higher CRFe is associated with lower health care costs. Cost savings were particularly evident in obese subjects, suggesting that the economic burden of obesity may be reduced through interventions that target improvements in CRF.

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