Article
Ecology
Eduardo L. Almeida, Celine Ribiere, Werner Frei, Denis Kenny, Mary F. Coffey, Paul W. O'Toole
Summary: In this study, the microbiome of honeybees from different time points in various apiaries across Ireland was analyzed. It was found that the microbiome composition showed stronger clustering by time point rather than by apiary site. The study also revealed certain bacteria in the honeybee microbiome that were correlated with hive health, highlighting the importance of the global honeybee microbiome in supporting thriving hives.
Article
Microbiology
Zijing Zhang, Xiaohuan Mu, Yao Shi, Hao Zheng
Summary: This study reveals the impact of gut bacteria on host metabolism, brain characteristics, and behavior in honeybees. Different gut bacteria regulate distinct circulating metabolites and gene expression patterns, influencing neural development and behavioral division of labor in bees. Furthermore, gut bacteria can alter neurotransmitter levels in the brain and affect taste-related behavior.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Margaret Steele, Erick V. S. Motta, Tejashwini Gattu, Daniel Martinez, Nancy A. Moran
Summary: Commensal microbes in animal guts play a role in excluding bacterial pathogens. In honey bees, disruption of the gut microbiota increases susceptibility to the opportunistic pathogen Serratia marcescens, which uses a T6SS to kill competitors in laboratory settings. However, within the bee gut, S. marcescens is rapidly eliminated in the presence of the microbiota and shows limited ability to compete with commensal species, indicating the importance of a healthy gut microbiota in protecting against pathogens.
MICROBIOLOGY SPECTRUM
(2021)
Article
Ecology
Leslie E. Decker, Priscilla A. San Juan, Magdalena L. Warren, Cory E. Duckworth, Cheng Gao, Tadashi Fukami
Summary: Fungi in the honey bee gut show less distinct species composition but greater variation compared to bacteria. The location where the bees were collected can predict the variation in fungal species composition. The study suggests that honey bees could be vectors of plant diseases.
Article
Multidisciplinary Sciences
Yuqi Wu, Yufei Zheng, Shuai Wang, Yanping Chen, Junyi Tao, Yanan Chen, Gongwen Chen, Hongxia Zhao, Kai Wang, Kun Dong, Fuliang Hu, Ye Feng, Huoqing Zheng
Summary: The intra-species diversity of gut microbiota in two closely related honey bee species, A. cerana and A. mellifera, shows distinct functional differences in core bacterial species between the hosts. However, the overall functional profiles of the gut microbiomes of the two honey bee species converge, likely due to overlapping ecological niches. This study provides critical insights into the evolution and functional roles of mutualistic microbiota in honey bees.
JOURNAL OF ADVANCED RESEARCH
(2022)
Article
Environmental Sciences
Zhi-Xiang Dong, Qi-He Tang, Wan-Li Li, Zheng-Wei Wang, Xi-Jie Li, Chao-Min Fu, Dan Li, Kai Qian, Wen-Li Tian, Jun Guo
Summary: Pesticide use poses a threat to honeybees, with deltamethrin being the most harmful. Deltamethrin exposure reduces bee survival and decreases diversity of the bee gut microbiota. Colonization of important gut bacteria improves bee resistance to deltamethrin and enhances host immunity.
ENVIRONMENTAL POLLUTION
(2022)
Article
Microbiology
Yujie Meng, Shuang Li, Chong Zhang, Hao Zheng
Summary: By using droplet-based microfluidic cultivation, researchers encapsulated and cultivated individual bacterial cells from the honeybee gut, leading to interesting findings. The cultivation technique revealed higher strain-level diversity compared to gut samples, and comparative genomic analysis provided insights into host adaptations.
Article
Environmental Sciences
Diego E. Vazquez, Luis E. Villegas Martinez, Virginia Medina, Jose M. Latorre-Estivalis, Jorge A. Zavala, Walter M. Farina
Summary: This study aims to determine whether glyphosate induces dysbiosis in honey bee larvae and affects their metamorphosis. Results indicate that intake of field-relevant concentrations of glyphosate slows down larval growth, induces dysbiosis in gut microbiota, and leads to teratogenesis and mortality of newly emerged bees.
ENVIRONMENTAL POLLUTION
(2023)
Article
Gastroenterology & Hepatology
Haijian Sun, Yunke Guo, Haidan Wang, Ailing Yin, Jing Hu, Tianjie Yuan, Shuxin Zhou, Weichen Xu, Peng Wei, Shusheng Yin, Panru Liu, Xi Guo, Yizhao Tang, Yujiao Yan, Zichen Luo, Majie Wang, Qingqing Liang, Peng Wu, Aifeng Zhang, Zhuxiu Zhou, Yueyue Chen, Yongming Li, Jing Li, Jinjun Shan, Wei Zhou
Summary: This study found that the food-derived Parabacteroides distasonis can ameliorate the development of rheumatoid arthritis (RA) and is negatively correlated with disease activity in RA patients. In addition, 3-oxoLCA and isoLCA can inhibit the development of RA by stimulating TGR5 and promoting macrophage polarization.
Article
Immunology
Ruqi Chang, Jieteng Chen, Zhaopeng Zhong, Yiyuan Li, Kaichun Wu, Hao Zheng, Yunsheng Yang
Summary: Patients with inflammatory bowel disease often experience cognitive impairment, but the underlying mechanism is unclear. In this study, researchers exposed honeybees to two different strains of E.coli and observed that the IBD-associated strain induced enteritis-like manifestations, cognitive behavioral modifications, increased gut permeability, and shortened lifespan in honeybees. The strain also altered the levels of certain substances in the honeybee gut and affected gene expression in the honeybee brain. This study suggests that honeybees can serve as a potential model for studying the microbiota-gut-brain interaction in IBD.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Lucsame Gruneck, Eleni Gentekaki, Kitiphong Khongphinitbunjong, Siam Popluechai
Summary: This study compared gut bacterial profiles of Asian honey bees and European honey bees, finding significant differences in gut bacterial communities between the two species. Bacteroides was more abundant in Asian honey bees, while Proteobacteria was higher in European honey bees. Different tasks performed by bees (nurse bees and foragers) were associated with specific gut bacterial species.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Microbiology
Yiyuan Li, Yan Zhang, Xi Luo, Yujie Meng, Zhaopeng Zhong, Hao Zheng, Yunsheng Yang
Summary: This study investigates the potential effects of fecal microbiota from children with autism and typical developmental (TD) children on honeybees. The findings suggest that the gut microbiota of children with autism influences the cognitive abilities and brain gene expression of honeybees, providing novel insights into the role of human gut microbiota in neurological processes.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Immunology
Roohollah Zarei Koosha, Parvindokht Fazel, Hamid Sedighian, Elham Behzadi, Mojtaba Ch Hedayati, Abbas Ali Imani Fooladi
Summary: Microbiota in the host play a crucial role in human health and disease, and understanding the principles of HostMicrobiota Interactions (HMIs) can help clarify the mechanisms of infections. The interactions between the host and microbiota can reveal new therapeutic pathways and potential microbial effects on the host.
MICROBIAL PATHOGENESIS
(2021)
Editorial Material
Biology
Aileen Berasategui, Hassan Salem
Summary: Honeybees use their gut symbionts to counteract a powerful toxin in pollen and nectar.
Article
Biology
Erick V. S. Motta, Alejandra Gage, Thomas E. Smith, Kristin J. Blake, Waldan K. Kwong, Ian M. Riddington, Nancy Moran, Hauke Koch
Summary: This study demonstrates the co-metabolism of dietary plant metabolites by both honey bees and their gut microbiota, revealing the mechanism of the combined involvement of the host and microbiota in the metabolism process.
Article
Evolutionary Biology
Waldan K. Kwong, Margaret I. Steele, Nancy A. Moran
GENOME BIOLOGY AND EVOLUTION
(2018)
Article
Cell Biology
Bjorn D. M. Bean, Samantha K. Dziurdzik, Kathleen L. Kolehmainen, Claire M. S. Fowler, Waldan K. Kwong, Leslie I. Grad, Michael Davey, Cayetana Schluter, Elizabeth Conibear
JOURNAL OF CELL BIOLOGY
(2018)
Article
Multidisciplinary Sciences
Alison McAfee, Abigail Chapman, Immacolata Iovinella, Ylonna Gallagher-Kurtzke, Troy F. Collins, Heather Higo, Lufiani L. Madilao, Paolo Pelosi, Leonard J. Foster
SCIENTIFIC REPORTS
(2018)
Article
Multidisciplinary Sciences
Waldan K. Kwong, Javier del Campo, Varsha Mathur, Mark J. A. Vermeij, Patrick J. Keeling
Article
Multidisciplinary Sciences
Hao Zheng, Julie Perreau, J. Elijah Powell, Benfeng Han, Zijing Zhang, Waldan K. Kwong, Susannah G. Tringe, Nancy A. Moran
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Biochemistry & Molecular Biology
Emma E. George, Filip Husnik, Daria Tashyreva, Galina Prokopchuk, Ales Horak, Waldan K. Kwong, Julius Lukes, Patrick J. Keeling
Editorial Material
Multidisciplinary Sciences
Waldan K. Kwong
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2020)
Editorial Material
Biochemistry & Molecular Biology
Waldan K. Kwong
Article
Biotechnology & Applied Microbiology
Alison McAfee, Joseph Milone, Abigail Chapman, Leonard J. Foster, Jeffery S. Pettis, David R. Tarpy
Article
Evolutionary Biology
Varsha Mathur, Waldan K. Kwong, Filip Husnik, Nicholas A. T. Irwin, Arni Kristmundsson, Camino Gestal, Mark Freeman, Patrick J. Keeling
Summary: The study sequenced the transcriptomes and apicoplast genomes of three deep-branching apicomplexans, revealing a new lineage that retains plastid genomes and the canonical apicomplexan plastid metabolism. This new lineage, proposed as Marosporida class nov., occupies an intermediate position in apicomplexan phylogeny and adds complexity to the stepwise reductive evolution models in these parasites.
GENOME BIOLOGY AND EVOLUTION
(2021)
Article
Biology
Alison McAfee, Abigail Chapman, Jeffery S. Pettis, Leonard J. Foster, David R. Tarpy
Summary: Research on honey bee queens has shown that factors affecting sperm viability include sperm quantity, health status, and spermathecal fluid proteins, with lysozyme correlating with the trade-off between reproduction and immunity.
COMMUNICATIONS BIOLOGY
(2021)
Article
Microbiology
Waldan K. Kwong, Nicholas A. T. Irwin, Varsha Mathur, Ina Na, Noriko Okamoto, Mark J. A. Vermeij, Patrick J. Keeling
Summary: Corals were found to host a diverse group of intracellular symbionts known colloquially as corallicolids. Through microscopic and molecular analysis, a new order and family, as well as two new species, were proposed to describe these organisms. Additionally, the reassignment of Gemmocystis cylindrus to the Corallicolida was suggested based on morphological and host localization similarities.
JOURNAL OF EUKARYOTIC MICROBIOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Alison McAfee, Abigail Chapman, Heather Higo, Robyn Underwood, Joseph Milone, Leonard J. Foster, M. Marta Guarna, David R. Tarpy, Jeffery S. Pettis
NATURE SUSTAINABILITY
(2020)