Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

Simultaneous Multicolor Single-Molecule Tracking with Single-Laser Excitation via Spectral Imaging

(2018) Tao Huang et al.   BIOPHYSICAL JOURNAL

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

(2017) Pau Pascual-Garcia et al.   MOLECULAR CELL

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

(2017) Kyong-Rim Kieffer-Kwon et al.   MOLECULAR CELL

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

(2017) Alicia N Schep et al.   NATURE METHODS

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

(2017) M Ryan Corces et al.   NATURE METHODS

How best to identify chromosomal interactions: a comparison of approaches

(2017) James O J Davies et al.   NATURE METHODS

Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

(2017) Inge M.N. Wortel et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

CTCF: making the right connections

(2016) Rodolfo Ghirlando et al.   GENES & DEVELOPMENT

Genome-wide mapping and analysis of chromosome architecture

(2016) Anthony D. Schmitt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The nuclear pore complex: understanding its function through structural insight

(2016) Martin Beck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pin1 promotes prostate cancer cell proliferation and migration through activation of Wnt/β-catenin signaling

(2015) Z. Zhu et al.   Clinical & Translational Oncology

Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins

(2015) Jennifer C. Harr et al.   JOURNAL OF CELL BIOLOGY

Three-dimensional genome architecture: players and mechanisms

(2015) Ana Pombo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc

(2015) Xiao-Xin Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity

(2015) Sara Helander et al.   STRUCTURE

Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation

(2015) Kevin Myant et al.   Cell Reports

Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem-like Cell Traits in Breast Cancer

(2014) M.-L. Luo et al.   CANCER RESEARCH

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

(2014) Danfeng Cai et al.   CELL

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

c-Myc-dependent transcriptional regulation of cell cycle and nucleosomal histones during oligodendrocyte differentiation

(2014) L. Magri et al.   NEUROSCIENCE

Photoactivated Localization Microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM) for Nanoscale Imaging of Protein-Protein Interactions in Cells

(2014) Andrew Nickerson et al.   PLoS One

MYC Activation Is a Hallmark of Cancer Initiation and Maintenance

(2014) M. Gabay et al.   Cold Spring Harbor Perspectives in Medicine

RNAi silencing of c-Myc inhibits cell migration, invasion, and proliferation in HepG2 human hepatocellular carcinoma cell line: c-Myc silencing in hepatocellular carcinoma cell

(2013) Yan Zhao et al.   Cancer Cell International

Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

(2013) A. S. Farrell et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamic Association of NUP98 with the Human Genome

(2013) Yun Liang et al.   PLoS Genetics

Nuclear pore proteins regulate chromatin structure and transcriptional memory by a conserved mechanism

(2013) William H Light et al.   Nucleus

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

A negative feedback loop at the nuclear periphery regulates GAL gene expression

(2012) Erin M. Green et al.   MOLECULAR BIOLOGY OF THE CELL

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

(2012) Yin C Lin et al.   NATURE IMMUNOLOGY

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes

(2012) M Niemelä et al.   ONCOGENE

Localization of Nucleoporin Tpr to the Nuclear Pore Complex Is Essential for Tpr Mediated Regulation of the Export of Unspliced RNA

(2012) Kalpana Rajanala et al.   PLoS One

N-Myc and GCN5 Regulate Significantly Overlapping Transcriptional Programs in Neural Stem Cells

(2012) Verónica Martínez-Cerdeño et al.   PLoS One

Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland

(2011) X. Wang et al.   CANCER RESEARCH

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription

(2011) Liangqi Xie et al.   EMBO JOURNAL

Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression

(2011) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

(2011) Yih-Cherng Liou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells

(2010) Kyoung Bin Cho et al.   CANCER LETTERS

Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes

(2010) Maya Capelson et al.   CELL

Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm

(2010) Bernike Kalverda et al.   CELL

Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

(2010) Sandra Krull et al.   EMBO JOURNAL

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

The ups and downs of Myc biology

(2009) Laura Soucek et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex

(2009) Sue Mei Tan-Wong et al.   GENES & DEVELOPMENT

Pin1 Promotes Transforming Growth Factor-β-induced Migration and Invasion

(2009) Isao Matsuura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

(2009) P. Hydbring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells

(2008) Tongzheng Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes

(2008) C. R. Brown et al.   GENES & DEVELOPMENT

Extracellular Signal-Regulated Kinase 2 (ERK2) Phosphorylation Sites and Docking Domain on the Nuclear Pore Complex Protein Tpr Cooperatively Regulate ERK2-Tpr Interaction

(2008) T. Vomastek et al.   MOLECULAR AND CELLULAR BIOLOGY

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

Identification of CDK2 substrates in human cell lysates

(2008) Yong Chi et al.   GENOME BIOLOGY