Structural basis for protein phosphatase 1 recruitment by glycogen-targeting subunits

Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis

(2017) Minal B. Mehta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors

(2017) Meng S. Choy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ablation of PPP1R3G reduces glycogen deposition and mitigates high-fat diet induced obesity

(2017) Yongxian Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2 -mediated stress signaling

(2016) C. X. Santos et al.   EMBO JOURNAL

The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

(2016) Ganesan Senthil Kumar et al.   eLife

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase

(2015) Meng S. Choy et al.   Cell Reports

G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases

(2015) Ruming Chen et al.   eLife

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

(2014) M. S. Choy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of human CRMP-4: correction of intensities for lattice-translocation disorder

(2014) Rajesh Ponnusamy et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Glycogen and its metabolism: some new developments and old themes

(2012) Peter J. Roach et al.   BIOCHEMICAL JOURNAL

Structural basis for protein phosphatase 1 regulation and specificity

(2012) Wolfgang Peti et al.   FEBS Journal

The PP1 binding code: a molecular-lego strategy that governs specificity

(2012) Ewald Heroes et al.   FEBS Journal

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme

(2012) Nichole O'Connell et al.   STRUCTURE

Differential pattern of glycogen accumulation after protein phosphatase 1 glycogen-targeting subunit PPP1R6 overexpression, compared to PPP1R3C and PPP1R3A, in skeletal muscle cells

(2011) Marta Montori-Grau et al.   BMC BIOCHEMISTRY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

(2010) Michael J Ragusa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein

(2010) Alexander Hirschi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Application of general formulas for the correction of a lattice-translocation defect in crystals of a lentiviral integrase in complex with LEDGF

(2009) Stephen Hare et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Comparative structural analyses of purified glycogen particles from rat liver, human skeletal muscle and commercial preparations

(2009) Je-Hoon Ryu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors

(2008) Matthew S. Kelker et al.   JOURNAL OF MOLECULAR BIOLOGY