Editorial Material
Cardiac & Cardiovascular Systems
Masashi Kawabori, Taylor Nordan, Navin K. Kapur, Gregory S. Couper
Summary: Right ventricular failure has a negative impact on prognosis post left ventricular assist device implantation. However, a strategy for primary prevention of right ventricular failure in high-risk patients has been proposed.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Taylor Merritt, Avihu Z. Gazit, Horacio Carvajal, Brock K. Montgomery, Mark Shepard, Mary Mehegan, Matthew Canter, Jacob Miller, Pirooz Eghtesady, Dilip S. Nath
Summary: The study outlines the experience of supporting 18 children with single ventricle (SV) physiology on ventricular assist devices (VADs), showing successful bridging to desired endpoints with proper patient selection and specific cannulation strategies.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Shusaku Maeda, Hidetsugu Asanoi, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Daisuke Yoshioka, Satoshi Kainuma, Masataka Igeta, Yoshiki Sawa
Summary: This study visualized the dynamic circulatory equilibrium of acute RVF after LVAD implantation using a new four-quadrant diagram, and stratified LVAD patients into different groups based on duration of postoperative inotropic support. The novel presentation showed characteristics such as increased CVP, relatively small increase in CI, and concomitant impairment of pressure natriuresis in acute RVF. The four-quadrant presentation serves as a useful guide for prompt and optimal management of circulatory malfunction.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Jared P. Beller, J. Hunter Mehaffey, Zachary K. Wegermann, Maria Grau-Sepulveda, Sean M. O'Brien, J. Matthew Brennan, Vinod Thourani, Vinay Badhwar, Francis D. Pagani, Gorav Ailawadi, Leora T. Yarboro, Nicholas R. Teman
Summary: Patients with severe right ventricular failure during durable left ventricular assist device implantation may benefit from the use of RVAD over VA-ECMO. Regardless of the type of support, initiation at the index operation was associated with improved outcomes.
ANNALS OF THORACIC SURGERY
(2022)
Review
Medicine, General & Internal
Gregory S. Troutman, Michael Genuardi
Summary: Survival rates for patients with end-stage heart failure continue to improve after implantation of a left ventricular assist device (LVAD). More patients are opting for long-term treatment with LVADs rather than bridge-to-transplant therapy, therefore it is crucial for healthcare providers to be familiar with the physiology, operation, and common complications of these devices. This review article provides an overview of the history, development, and operation of modern LVADs, as well as a discussion of common complications and suggested approaches to LVAD patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Anubodh S. Varshney, Ersilia M. DeFilippis, Jennifer A. Cowger, Ivan Netuka, Sean P. Pinney, Michael M. Givertz
Summary: With the increasing prevalence of advanced heart failure, treatment options such as heart transplantation and LVAD support have shown to improve quality of life and extend survival. Recent advancements, including the use of HeartMate 3 in clinical practice and revisions to the organ allocation system, have led to better management of LVAD-related complications. Although contemporary LVAD recipients have higher illness severity preoperatively, they have higher survival rates and lower adverse event rates compared to previous eras. However, challenges such as bleeding, infection, neurologic events, and right ventricular failure still limit the wider implementation of LVAD support. Ongoing efforts to optimize management of current LVAD devices and develop next-generation devices are expected to further enhance outcomes for patients with advanced heart failure.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Alessia Gambaro, Gianmarco Lombardi, Francesco Onorati, Leonardo Gottin, Flavio Luciano Ribichini
Summary: LVAD implantation has complex effects on the kidneys, particularly regarding renal function. Creatinine-based eGFR formulas help in assessing patient prognosis, while deterioration in renal function in LVAD patients negatively impacts outcomes.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Cardiac & Cardiovascular Systems
Mahmood Abu Akel, Aviv A. Shaul, Gustavo R. Goldenberg, Yaron D. Barac, Binyamin Ben-Avraham, Dan Gorfil, Dan Aravot, Tuvia Ben-Gal
Summary: This case report describes the successful heart transplantation of a patient with ventricular arrhythmia who was treated with combined LVAD and VA ECMO, effectively controlling heart failure and achieving good clinical outcomes.
Article
Critical Care Medicine
Auriane Bidaut, Erwan Flecher, Nicolas Nesseler, Karl Bounader, Andre Vincentelli, Mouhammed Moussa, Clement Delmas, Jean Porterie, Karine Nubret, Mathieu Pernot, Michel Kindo, Clement Schneider, Philippe Gaudard, Philippe Rouviere, Magali Michel, Thomas Senage, Aude Boignard, Olivier Chavanon, Constance Verdonk, Marylou Para, Baptiste Maille, Vlad Gariboldi, Matteo Pozzi, Elisabeth Hugon-Vallet, Pierre-Yves Litzler, Frederic Anselme, Katrien Blanchart, Gerard Babatasi, Marie Bielefeld, Sandrine Grosjean, Costin Radu, David Hamon, Thierry Bourguignon, Thibaud Genet, Romain Eschalier, Nicolas D'Ostrevy, Helene Nougue, Anne Cecile Martin, Fabrice Vanhuyse, Hugues Blangy, Christophe Leclercq, Raphael P. Martins, Vincent Galand
Summary: The study aimed to analyze the outcome of temporary circulatory support (TCS) strategy as a bridge-to-left ventricular assist device (BTL) in cardiogenic shock patients and identify predictors of postoperative mortality. The results showed that there was no significant difference in 30-day survival between the TCS group and the non-TCS group, but the TCS group had a longer ICU duration stay. Combined surgery with LVAD, higher BMI, and HF duration were identified as independent predictors of mortality in the TCS group.
CRITICAL CARE MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mehmet H. Akay, Mateja K. Jezovnik, Ismael A. Salas De Armas, Milica Ilic, Mehmet N. Karabulut, Mehmet Alagoz, Manish Patel, Rajko Radovancevic, Biswajit Kar, Igor D. Gregoric
Summary: A retrospective analysis was conducted to compare the incidence of LVAD-related infections between patients who underwent delayed sternal closure and primary sternal closure after LVAD implantation surgery. The study found that delayed sternal closure does not increase the risk of LVAD-related infections in heart failure patients.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Cardiac & Cardiovascular Systems
Guillaume Baudry, Nicolas Nesseler, Erwan Flecher, Andre Vincentelli, Celine Goeminne, Clement Delmas, Jean Porterie, Karine Nubret, Mathieu Pernot, Michel Kindo, Tam Hoang Minh, Philippe Rouviere, Philippe Gaudard, Magali Michel, Thomas Senage, Aude Boignard, Olivier Chavanon, Marylou Para, Constance Verdonk, Edeline Pelce, Vlad Gariboldi, Frederic Anselme, Pierre-Yves Litzler, Katrien Blanchart, Gerard Babatasi, Marie Bielefeld, Olivier Bouchot, David Hamon, Nicolas Lellouche, Xavier Bailleul, Thibaud Genet, Romain Eschalier, Nicolas d'Ostrevy, Marie-Cecile Bories, Ramzi Abi Akar, Hugues Blangy, Fabrice Vanhuyse, Jean Francois Obadia, Vincent Galand, Matteo Pozzi
Summary: Despite updated guidelines, there is still a delay in referring advanced heart failure patients for mechanical circulatory support and transplants. This study analyzed the characteristics and outcomes of non-inotrope-dependent patients with LVAD, finding unsatisfactory survival rates. Age, concomitant procedures, and temporary mechanical right ventricular support during LVAD implantation were identified as independent variables associated with mortality.
Article
Cardiac & Cardiovascular Systems
Makiko Nakamura, Teruhiko Imamura, Takuya Fukui, Akira Oshima, Hiroshi Ueno, Koichiro Kinugawa
Summary: There is currently no established therapeutic strategy for pheochromocytoma-related cardiogenic shock. We report a case of a 51-year-old male patient with acute decompensated heart failure due to pheochromocytoma crisis, who underwent successful adrenalectomy following treatment with a percutaneous left ventricular assist device and medication. Early suspicion of pheochromocytoma and disease-specific medical management supported by Impella may provide a promising bridge to surgery.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Cardiac & Cardiovascular Systems
Nicole K. Bart, Desire Robson, Kavitha Muthiah, Paul C. Jansz, Christopher S. Hayward
Summary: This study aimed to determine the frequency and outcomes of autopsy investigations in patients who died prior to heart transplantation after receiving permanent mechanical circulatory support.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Chemistry, Multidisciplinary
Dmitry V. Telyshev, Alexander A. Pugovkin, Ivan A. Ephimov, Aleksandr Markov, Steffen Leonhardt, Marian Walter, Jamshid H. Karimov, Sergey V. Selishchev
Summary: This study evaluates the electric current parameters and analyzes the degree of myocardial function during LVAD support. It finds a correlation between cardiac output and the pulsatility index of the pump electric current, suggesting the potential use of these parameters as a clinical tool for assessing myocardial therapy using LVAD infrastructure.
APPLIED SCIENCES-BASEL
(2021)
Article
Cardiac & Cardiovascular Systems
Fabian Jimenez Contreras, Michelle Mendiola Pla, Jacob Schroder, Benjamin Bryner, Richa Agarwal, Stuart D. Russell, Jacqueline Mirza, Mani A. Daneshmand, Carmelo Milano
Summary: Long-term LVAD support can accelerate the progression of AI. The HM3 LVAD, with greater hemocompatibility, is compared to HM2 in terms of the rate of MSAI progression.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Tim Kambic, Borut Jug, Massimo Francesco Piepoli, Mitja Lainscak
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Federica Toto, Elisabetta Salvioni, Damiano Magri, Susanna Sciomer, Massimo Piepoli, Roberto Badagliacca, Arianna Galotta, Nikita Baracchini, Stefania Paolillo, Ugo Corra, Rosa Raimondo, Rocco Lagioia, Pasquale Perrone Filardi, Annamaria Iorio, Michele Senni, Michele Correale, Mariantonietta Cicoira, Enrico Perna, Marco Metra, Marco Guazzi, Giuseppe Limongelli, Gianfranco Sinagra, Gianfranco Parati, Gaia Cattadori, Francesco Bandera, Maurizio Bussotti, Massimo Mapelli, Manlio Cipriani, Alice Bonomi, Goncalo Cunha, Federica Re, Carlo Vignati, Andrea Garascia, Carlo Lombardi, Angela B. Scardovi, Andrea Passantino, Michele Emdin, Claudio Passino, Caterina Santolamazza, Davide Girola, Denise Zaffalon, Dario Vizza, Fabiana De Martino, Piergiuseppe Agostoni
Summary: This study aimed to assess the prognostic impact of moderate hyperkalemia in chronic HFrEF patients and found that it does not influence patients' outcome.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Oliver O'Sullivan, Rienk Rienks, David Holdsworth, Constantinos H. Davos, Martin Halle, Alexander Bennett, Gianfranco Parati, Norbert Guettler, Edward Nicol
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Roberto F. E. Pedretti, Dominique Hansen, Marco Ambrosetti, Maria Back, Thomas Berger, Mariana Cordeiro Ferreira, Veronique Cornelissen, Constantinos H. Davos, Wolfram Doehner, Carmen de Pablo Y. Zarzosa, Ines Frederix, Andrea Greco, Donata Kurpas, Matthias Michal, Elena Osto, Susanne Pedersen, Rita Esmeralda Salvador, Maria Simonenko, Patrizia Steca, David R. Thompson, Matthias Wilhelm, Ana Abreu
Summary: Optimal patient adherence to treatment is crucial for successful secondary prevention of cardiovascular disease (CVD). However, unsatisfactory adherence rates have been consistently observed for CVD risk factors and treatment. This consensus document provides a modern reappraisal of adherence to optimal treatment and offers simple, practical, and feasible suggestions to achieve this goal in the clinical setting, focusing on evidence-based concepts.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Geza Halasz, Francesco Bandera, Massimo Piepoli
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Geza Halasz, Francesco Bandera, Guido Giacalone, Massimo Piepoli
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Andrea Attanasio, Massimo F. Piepoli
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Gianfranci Parati, Massimo Piepoli
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Health Care Sciences & Services
Marco Alfonso Perrone, Ferdinando Iellamo, Valentino D'Antoni, Alessandro Gismondi, Deborah Di Biasio, Sara Vadala, Giuseppe Marazzi, Valentina Morsella, Maurizio Volterrani, Giuseppe Caminiti
Summary: This study aimed to assess acute changes in left atrial (LA) function during incremental aerobic exercise in heart failure patients and compare them with healthy subjects. The results showed that patients with mildly reduced ejection fraction showed a proper increase in LA reservoir function, which helped maintain stroke volume during exercise.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Giuseppe Caminiti, Marco Alfonso Perrone, Valentino DAntoni, Giuseppe Marazzi, Alessandro Gismondi, Sara Vadala, Deborah Di Biasio, Vincenzo Manzi, Ferdinando Iellamo, Maurizio Volterrani
Summary: Left atrial dysfunction is associated with exercise intolerance and poor prognosis in heart failure (HF). The effects of exercise training on atrial function in patients with HF with mid-range ejection fraction (HFmrEF) are unknown. This study aimed to assess the effects of a supervised concurrent training (SCT) program on left atrial function in HFmrEF patients. Results showed that SCT improved left atrial and left ventricular function in HFmrEF, with significant increases in exercise duration, distance walked, and measures of atrial strain compared to the control group.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Correction
Cardiac & Cardiovascular Systems
M. Riccardi, A. M. Sammartino, M. Piepoli, M. Adamo, M. Pagnesi, G. Rosano, M. Metra, S. von Haehling, D. Tomasoni
Correction
Cardiac & Cardiovascular Systems
Massimo F. Piepoli, Marianna Adamo, Andrea Barison, Reinaldo B. Bestetti, Jan Biegus, Michael Bohm, Javed Butler, Jonathan Carapetis, Claudio Ceconi, Ovidiu Chioncel, Andrew Coats, Maria G. Crespo-Leiro, Giovanni de Simone, Heinz Drexel, Michele Emdin, Dimitros Farmakis, Martin Halle, Stephane Heymans, Tiny Jaarsma, Ewa Jankowska, Mitja Lainscak, Carolyn S. P. Lam, Maja-Lisa Lochen, Yuri Lopatin, Aldo Maggioni, Benedetta Matrone, Marco Metra, Katharine Noonan, Ileana Pina, Eva Prescott, Giuseppe Rosano, Petar M. Seferovic, Karen Sliwa, Simon Stewart, Alicia Uijl, Ilonca Vaartjes, Roel Vermeulen, W. M. Verschuren, Maurizio Volterrani, Stephan Von Haehling, Arno Hoes
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Correction
Cardiac & Cardiovascular Systems
[Anonymous]
EUROPEAN HEART JOURNAL
(2023)
Correction
Cardiac & Cardiovascular Systems
Suleman Aktaa, Gorav Batra, John G. F. Cleland, Andrew Coats, Lars H. Lund, Theresa McDonagh, Giuseppe Rosano, Petar Seferovic, Peter Vasko, Lars Wallentin, Aldo P. Maggioni, Barbara Casadei, Chris P. Gale
EUROPEAN HEART JOURNAL
(2023)