High-throughput screening and environmental risk assessment: State of the science and emerging applications

Adverse outcome pathway networks II: Network analytics

(2018) Daniel L. Villeneuve et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathway networks I: Development and applications

(2018) Dries Knapen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive

(2018) Beate I. Escher et al.   SCIENCE OF THE TOTAL ENVIRONMENT

In vitro to in vivo extrapolation for high throughput prioritization and decision making

(2018) Shannon M. Bell et al.   TOXICOLOGY IN VITRO

The US Federal Tox21 Program: A strategic and operational plan for continued leadership

(2018) Russell Thomas   ALTEX-Alternatives to Animal Experimentation

Incorporating suborganismal processes into dynamic energy budget models for ecological risk assessment

(2018) Cheryl A Murphy et al.   Integrated Environmental Assessment and Management

Uncertainty quantification in ToxCast high throughput screening

(2018) Eric D. Watt et al.   PLoS One

Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results

(2018) Carlie A. LaLone et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

An “EAR” on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure–Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters

(2017) Brett R. Blackwell et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development

(2017) You Song et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Identification of Unknown Antiandrogenic Compounds in Surface Waters by Effect-Directed Analysis (EDA) Using a Parallel Fractionation Approach

(2017) Matthias Muschket et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology

(2017) Rory B. Conolly et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A cell-free testing platform to screen chemicals of potential neurotoxic concern across twenty vertebrate species

(2017) Adeline Arini et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

A framework for predicting impacts on ecosystem services from (sub)organismal responses to chemicals

(2017) Valery E. Forbes et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water

(2017) Peta A. Neale et al.   WATER RESEARCH

The CompTox Chemistry Dashboard: a community data resource for environmental chemistry

(2017) Antony J. Williams et al.   Journal of Cheminformatics

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

(2016) Ann M. Richard et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals

(2016) Laura N. Vandenberg et al.   Environmental Health

Environmental surveillance and monitoring-The next frontiers for high-throughput toxicology

(2016) Anthony L. Schroeder et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Predicting environmental risk: A road map for the future

(2016) Tjalling Jager   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Effect-directed analysis supporting monitoring of aquatic environments — An in-depth overview

(2016) Werner Brack et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Editor’s Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity

(2016) Carlie A. LaLone et al.   TOXICOLOGICAL SCIENCES

Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries

(2016) Katie Paul Friedman et al.   TOXICOLOGICAL SCIENCES

High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes

(2015) David M. Reif et al.   ARCHIVES OF TOXICOLOGY

Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling

(2015) Peta A. Neale et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Incorporating High-Throughput Exposure Predictions With Dosimetry-AdjustedIn VitroBioactivity to Inform Chemical Toxicity Testing

(2015) Barbara A. Wetmore et al.   TOXICOLOGICAL SCIENCES

In Vitroand Modelling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Programme

(2014) Richard Judson et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Application of Mass Balance Models and the Chemical Activity Concept To Facilitate the Use of in Vitro Toxicity Data for Risk Assessment

(2014) James M. Armitage et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Improving the Human Hazard Characterization of Chemicals: A Tox21 Update

(2013) Raymond R. Tice et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Most Oxidative Stress Response In Water Samples Comes From Unknown Chemicals: The Need For Effect-Based Water Quality Trigger Values

(2013) Beate I. Escher et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment

(2013) Jos G. Bessems et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Developing Predictive Approaches to Characterize Adaptive Responses of the Reproductive Endocrine Axis to Aromatase Inhibition: I. Data Generation in a Small Fish Model

(2013) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

(2012) Robert Kavlock et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment

(2011) Richard S. Judson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Vision & strategy: Predictive ecotoxicology in the 21st century

(2010) Daniel L. Villeneuve et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The Toxicity Data Landscape for Environmental Chemicals

(2008) Richard Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES