Gamma-H2AX immunofluorescence for the detection of tissue-specific genotoxicity in vivo

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Inter-laboratory comparison of the in vivo comet assay including three image analysis systems

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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

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The JaCVAM international validation study on the in vivo comet assay: Selection of test chemicals

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Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

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Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

The γH2AX Assay for Genotoxic and Nongenotoxic Agents: Comparison of H2AX Phosphorylation with Cell Death Response

(2014) Teodora Nikolova et al.   TOXICOLOGICAL SCIENCES

Influence of experimental conditions on data variability in the liver comet assay

(2013) M. Guérard et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Genotoxicity of doxorubicin in F344 rats by combining the comet assay, flow-cytometric peripheral blood micronucleus test, and pathway-focused gene expression profiling

(2013) Mugimane G. Manjanatha et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Exercise preconditioning modulates genotoxicity induced by doxorubicin in multiple organs of rats

(2012) Renato Almeida Martins et al.   CELL BIOCHEMISTRY AND FUNCTION

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Tissue retention of doxorubicin and its effects on cardiac, smooth, and skeletal muscle function

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Chemotherapy-Induced Weakness and Fatigue in Skeletal Muscle: The Role of Oxidative Stress

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DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression

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Differences in accumulation of anthracyclines daunorubicin, doxorubicin and epirubicin in rat tissues revealed by immunocytochemistry

(2010) Masashi Shin et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

(2010) Andreas Rothfuss et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing

(2010) Andreas Rothfuss et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Doxorubicin acts through tumor necrosis factor receptor subtype 1 to cause dysfunction of murine skeletal muscle

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H2AX phosphorylation as a genotoxicity endpoint

(2009) Gary Peter Watters et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vivo and in vitro characterization of ethyl methanesulfonate pharmacokinetics in animals and in human

(2009) Thierry Lavé et al.   TOXICOLOGY LETTERS

Oxidative stress as a therapeutic target during muscle wasting: considering the complex interactions

(2008) Peter G Arthur et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Detection of photogenotoxicity in skin and eye in rat with the photo comet assay

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