Is interleukin-1β a culprit in macrophage-adipocyte crosstalk in obesity?

Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes

(2014) Dan Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Double-Blind, Randomized Study Evaluating the Glycemic and Anti-inflammatory Effects of Subcutaneous LY2189102, a Neutralizing IL-1  Antibody, in Patients With Type 2 Diabetes

(2013) J. Sloan-Lancaster et al.   DIABETES CARE

The role of interleukin 1β in the anti-adipogenic action of macrophages on human preadipocytes

(2013) AnneMarie Gagnon et al.   JOURNAL OF ENDOCRINOLOGY

Interleukin-1β Downregulates RBP4 Secretion in Human Adipocytes

(2013) Primoz Kotnik et al.   PLoS One

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

(2013) J. I. Odegaard et al.   SCIENCE

CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

(2012) H. Kitade et al.   DIABETES

Identification of Adipose Tissue Dendritic Cells Correlated With Obesity-Associated Insulin-Resistance and Inducing Th17 Responses in Mice and Patients

(2012) A. Bertola et al.   DIABETES

Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

(2012) C. Cavelti-Weder et al.   DIABETES CARE

Inflammation links excess fat to insulin resistance: the role of the interleukin-1 family

(2012) Cees J. Tack et al.   IMMUNOLOGICAL REVIEWS

1,25-Dihydroxyvitamin D3 inhibits the cytokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes

(2012) D Gao et al.   INTERNATIONAL JOURNAL OF OBESITY

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

The Inflammasome and Caspase-1 Activation: A New Mechanism Underlying Increased Inflammatory Activity in Human Visceral Adipose Tissue

(2011) Tim B. Koenen et al.   ENDOCRINOLOGY

Macrophage-induced expression and release of matrix metalloproteinase 1 and 3 by human preadipocytes is mediated by IL-1β via activation of MAPK signaling

(2011) Dan Gao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

(2010) Rinke Stienstra et al.   Cell Metabolism

Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity

(2010) J. M. Wentworth et al.   DIABETES

XOMA 052, an Anti-IL-1β Monoclonal Antibody, Improves Glucose Control and β-Cell Function in the Diet-Induced Obesity Mouse Model

(2010) Alexander M. Owyang et al.   ENDOCRINOLOGY

Macrophage-secreted factors inhibit ZAG expression and secretion by human adipocytes

(2010) D. Gao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Effect of the Interleukin-1 Cytokine Family Members IL-1F6 and IL-1F8 on Adipocyte Differentiation

(2010) Edwin J.P. van Asseldonk et al.   Obesity

CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue

(2009) Mayoura Keophiphath et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat

(2009) J. A. Ehses et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Antiinflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High-Fat Diet-Induced Hyperglycemia

(2008) Nadine S. Sauter et al.   ENDOCRINOLOGY