期刊
DRUG DEVELOPMENT RESEARCH
卷 80, 期 1, 页码 24-27出版社
WILEY
DOI: 10.1002/ddr.21482
关键词
antibiotics; biodiscovery; marine bacteria; marine fungi; marine natural products
资金
- EU FP7 KBBE project Marine Fungi [265926]
- Ministry of Science, Economic Affairs and Transport of the State of Schleswig-Holstein (Germany)
- European Union (EFRE)
Natural products and derivatives thereof are of considerable importance in the discovery of new pharmaceuticals, for example, for the treatment of cancer, diabetes, inflammation diseases, and infection diseases caused by bacteria, fungi, viruses, or parasites. The great biodiversity of marine microorganisms is reflected in their huge chemical diversity, which provides a rich source of biologically active compounds. An increasing interest in marine microorganisms as promising producers of new compounds with potential medical applications has raised increasing interest in the sustainable exploration of marine microbial resources for the discovery of new antibiotics, which is highlighted. The bottlenecks in the development of drugs using the large marine natural product pipeline are also discussed.
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