MicroRNA-21-5p are involved in apoptosis and invasion of fibroblast-like synoviocytes through PTEN/PI3K/AKT signal

Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes

(2018) Man Wai Tang et al.   RHEUMATOLOGY

Apoptotic and Anti-Inflammatory Effects of Eupatorium japonicum Thunb. in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

(2018) Jong-Il Shin et al.   Biomed Research International

Ectopic RASGRP2 (CalDAG-GEFI) expression in rheumatoid synovium contributes to the development of destructive arthritis

(2018) Hiroyuki Nakamura et al.   ANNALS OF THE RHEUMATIC DISEASES

MiR-21 regulates the ACAT1 gene in MCF-7 cells

(2018) M.D. Chanyshev et al.   LIFE SCIENCES

Total flavonoids from Smilax glabra Roxb blocks epithelial-mesenchymal transition and inhibits renal interstitial fibrosis by targeting miR-21/PTEN signaling

(2018) Qihan Luo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Indirubin inhibits the migration, invasion, and activation of fibroblast-like synoviocytes from rheumatoid arthritis patients

(2017) Mingcheng Huang et al.   INFLAMMATION RESEARCH

Tamarixinin A Alleviates Joint Destruction of Rheumatoid Arthritis by Blockade of MAPK and NF-κB Activation

(2017) Yuanyuan Zhuang et al.   Frontiers in Pharmacology

Synovium-Derived MicroRNAs Regulate Bone Pathways in Rheumatoid Arthritis

(2016) Yukiko Maeda et al.   JOURNAL OF BONE AND MINERAL RESEARCH

MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway

(2016) Chen Lv et al.   TUMOR BIOLOGY

MicroRNA-21 Promotes Proliferation of Fibroblast-Like Synoviocytes through Mediation of NF-κB Nuclear Translocation in a Rat Model of Collagen-Induced Rheumatoid Arthritis

(2016) Ying Chen et al.   Biomed Research International

The PI3K/Akt/PTEN/mTOR pathway: a fruitful target for inducing cell death in rheumatoid arthritis?

(2015) Charles J Malemud   Future Medicinal Chemistry

Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis

(2015) L Venturutti et al.   ONCOGENE

Programmed cell death 4 and microRNA 21 inverse expression is maintained in cells and exosomes from ovarian serous carcinoma effusions

(2014) Rocco Cappellesso et al.   CANCER CYTOPATHOLOGY

Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs

(2014) K Smigielska-Czepiel et al.   GENES AND IMMUNITY

Impact of microRNAs on the understanding and treatment of rheumatoid arthritis

(2013) Meryem Ammari et al.   CURRENT OPINION IN RHEUMATOLOGY

Dual Role of miR-21 in CD4+ T-Cells: Activation-Induced miR-21 Supports Survival of Memory T-Cells and Regulates CCR7 Expression in Naive T-Cells

(2013) Katarzyna Smigielska-Czepiel et al.   PLoS One

The role of synovitis in osteoarthritis pathogenesis

(2012) Carla R. Scanzello et al.   BONE

MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis

(2012) Florian Meisgen et al.   EXPERIMENTAL DERMATOLOGY

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

(2012) E. Choy   RHEUMATOLOGY

Circulating microRNAs as candidate biomarkers in patients with systemic lupus erythematosus

(2012) Honglei Wang et al.   Translational Research

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

(2012) Anak ASSK Dharmapatni et al.   ARTHRITIS RESEARCH & THERAPY

miRNAs and related polymorphisms in rheumatoid arthritis susceptibility

(2011) Anthoula Chatzikyriakidou et al.   AUTOIMMUNITY REVIEWS

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

Cell death in rheumatoid arthritis

(2009) Adelheid Korb et al.   APOPTOSIS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS