Underscoring interstrain variability and the impact of growth conditions on associated antimicrobial susceptibilities in preclinical testing of novel antimicrobial drugs

Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of α-toxin

(2018) Simone Keitsch et al.   BIOLOGICAL CHEMISTRY

Mathematical modelling of temperature effect on growth kinetics of Pseudomonas spp. on sliced mushroom ( Agaricus bisporus )

(2018) Fatih Tarlak et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The ideal time of systemic metronidazole and amoxicillin administration in the treatment of severe periodontitis: study protocol for a randomized controlled trial

(2018) Magda Feres et al.   Trials

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments

(2018) Matthew J. Pestrak et al.   PLoS Pathogens

Phenalen-1-one-Mediated Antimicrobial Photodynamic Therapy: Antimicrobial Efficacy in a Periodontal Biofilm Model and Flow Cytometric Evaluation of Cytoplasmic Membrane Damage

(2018) Fabian Cieplik et al.   Frontiers in Microbiology

Activity of the novel siderophore cephalosporin cefiderocol against multidrug-resistant Gram-negative pathogens

(2017) J. Dobias et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Microbial variability in growth and heat resistance of a pathogen and a spoiler: All variabilities are equal but some are more equal than others

(2017) Heidy M.W. den Besten et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Incentivising innovation in antibiotic drug discovery and development: progress, challenges and next steps

(2017) Victoria L Simpkin et al.   JOURNAL OF ANTIBIOTICS

Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

(2017) Brittany B. Lewis et al.   mBio

Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps

(2017) Jorge Olivares Pacheco et al.   mBio

In VitroActivity of Delafloxacin Tested against Isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis

(2016) Robert K. Flamm et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivity of Ceftazidime-Avibactam against Contemporary Pseudomonas aeruginosa Isolates from U.S. Medical Centers by Census Region, 2014

(2016) Michael D. Huband et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The hidden societal cost of antibiotic resistance per antibiotic prescribed in the United States: an exploratory analysis

(2016) Constantinos I. Michaelidis et al.   BMC INFECTIOUS DISEASES

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Theo Vos et al.   LANCET

Antimicrobial Susceptibility of Enteric Gram Negative Facultative Anaerobe Bacilli in Aerobic versus Anaerobic Conditions

(2016) Zachary DeMars et al.   PLoS One

Failure of Investigational Drugs in Late-Stage Clinical Development and Publication of Trial Results

(2016) Thomas J. Hwang et al.   JAMA Internal Medicine

Penetration barrier contributes to bacterial biofilm-associated resistance against only select antibiotics, and exhibits genus-, strain- and antibiotic-specific differences

(2016) Rachna Singh et al.   Pathogens and Disease

Candida albicansBiofilms and Human Disease

(2015) Clarissa J. Nobile et al.   Annual Review of Microbiology

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

(2015) Jonathan Jantsch et al.   Cell Metabolism

Ceftazidime-avibactam activity when tested against ceftazidime-nonsusceptible Citrobacter spp., Enterobacter spp., Serratia marcescens, and Pseudomonas aeruginosa from Unites States medical centers (2011–2014)

(2015) Helio S. Sader et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Presence ofPseudomonas aeruginosainfluences biofilm formation and surface protein expression ofStaphylococcus aureus

(2015) Amit Kumar et al.   ENVIRONMENTAL MICROBIOLOGY

Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy

(2015) Françoise Van Bambeke   Future Microbiology

Novel antibiotics: Are we still in the pre–post-antibiotic era?

(2015) R. Draenert et al.   INFECTION

The transcriptomic response ofAcinetobacter baumanniito colistin and doripenem alone and in combination in anin vitropharmacokinetics/pharmacodynamics model

(2015) Rebekah Henry et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors

(2015) Hong-Yu Ou et al.   Scientific Reports

Sheltering Effect and Indirect Pathogenesis of Carbapenem-Resistant Acinetobacter baumannii in Polymicrobial Infection

(2014) Yu-Ting Liao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials

(2014) Abrar K Thabit et al.   EXPERT OPINION ON PHARMACOTHERAPY

Heteroresistance of Helicobacter pylori from the same patient prior to antibiotic treatment

(2014) Cheng-Yen Kao et al.   INFECTION GENETICS AND EVOLUTION

Looking Back to the Future: Predicting in Vivo Efficacy of Small Molecules versus Mycobacterium tuberculosis

(2014) Sean Ekins et al.   Journal of Chemical Information and Modeling

Bigger data, collaborative tools and the future of predictive drug discovery

(2014) Sean Ekins et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

N-Chloramines, a Promising Class of Well-Tolerated Topical Anti-Infectives

(2013) Waldemar Gottardi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The role of bacterial biofilms in chronic infections

(2013) Thomas Bjarnsholt   APMIS

Antimicrobial Resistance and Virulence: a Successful or Deleterious Association in the Bacterial World?

(2013) A. Beceiro et al.   CLINICAL MICROBIOLOGY REVIEWS

Clinical isolates and laboratory referenceCandidaspecies and strains have varying abilities to form biofilms

(2013) Ali D. Alnuaimi et al.   FEMS YEAST RESEARCH

Rifampin Heteroresistance in Mycobacterium tuberculosis Cultures as Detected by Phenotypic and Genotypic Drug Susceptibility Test Methods

(2013) D. B. Folkvardsen et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Quantification of Subgingival Bacterial Pathogens at Different Stages of Periodontal Diseases

(2012) Heon-Jin Lee et al.   CURRENT MICROBIOLOGY

Easy Strategy To Increase Salt Resistance of Antimicrobial Peptides

(2011) Hui-Yuan Yu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antagonistic Interactions of Pseudomonas aeruginosa Antibiotic Resistance Mechanisms in Planktonic but Not Biofilm Growth

(2011) Xavier Mulet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phosphoethanolamine Modification of Lipid A in Colistin-Resistant Variants of Acinetobacter baumannii Mediated by the pmrAB Two-Component Regulatory System

(2011) Alejandro Beceiro et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomic Plasticity of the Human Fungal Pathogen Candida albicans

(2010) Anna Selmecki et al.   EUKARYOTIC CELL

Effect of the growth environment on the strain variability of Salmonella enterica kinetic behavior

(2010) Alexandra Lianou et al.   FOOD MICROBIOLOGY

The K1 Capsular Polysaccharide of Acinetobacter baumannii Strain 307-0294 Is a Major Virulence Factor

(2010) T. A. Russo et al.   INFECTION AND IMMUNITY

Essential Role for the Major Autolysin in the Fibronectin-Binding Protein-MediatedStaphylococcus aureusBiofilm Phenotype

(2010) Patrick Houston et al.   INFECTION AND IMMUNITY

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antibiotic resistance and its cost: is it possible to reverse resistance?

(2010) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

Detection of Enterococcus Faecalis in subgingival biofilm of patients with chronic refractory periodontitis

(2010) E. Balaei-Gajan et al.   Medicina Oral Patologia Oral y Cirugia Bucal

Hospital and Societal Costs of Antimicrobial‐Resistant Infections in a Chicago Teaching Hospital: Implications for Antibiotic Stewardship

(2009) Rebecca R. Roberts et al.   CLINICAL INFECTIOUS DISEASES