The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia

Rationale for an adjunctive therapy with fenofibrate in pharmacoresistant nocturnal frontal lobe epilepsy

(2017) Monica Puligheddu et al.   EPILEPSIA

Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes

(2017) M Maekawa et al.   Translational Psychiatry

Antidepressant-like effects of fenofibrate in mice via the hippocampal brain-derived neurotrophic factor signalling pathway

(2016) Bo Jiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Maternal Immune Activation Disrupts Dopamine System in the Offspring

(2016) Antonio Luchicchi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

PPARα modulation of mesolimbic dopamine transmission rescues depression-related behaviors

(2016) Simona Scheggi et al.   NEUROPHARMACOLOGY

Sexually dimorphic effects of prenatal exposure to lipopolysaccharide, and prenatal and postnatal exposure to propionic acid, on acoustic startle response and prepulse inhibition in adolescent rats: Relevance to autism spectrum disorders

(2015) Kelly A. Foley et al.   BEHAVIOURAL BRAIN RESEARCH

Prenatal LPS-exposure – a neurodevelopmental rat model of schizophrenia – differentially affects cognitive functions, myelination and parvalbumin expression in male and female offspring

(2015) Lena Wischhof et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Using a maternal immune stimulation model of schizophrenia to study behavioral and neurobiological alterations over the developmental course

(2015) Ravit Hadar et al.   SCHIZOPHRENIA RESEARCH

Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress

(2015) Roberto Frau et al.   SCHIZOPHRENIA RESEARCH

Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain

(2014) P Basil et al.   Translational Psychiatry

Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems

(2013) Urs Meyer   BIOLOGICAL PSYCHIATRY

Physiological Role of Peroxisome Proliferator-Activated Receptors Type Alpha on Dopamine Systems

(2013) Miriam Melis et al.   CNS & Neurological Disorders-Drug Targets

Therapeutic Prospects of PPARs in Psychiatric Disorders: A Comprehensive Review

(2013) Benjamin Rolland et al.   CURRENT DRUG TARGETS

PPAR-Alpha Agonists as Novel Antiepileptic Drugs: Preclinical Findings

(2013) Monica Puligheddu et al.   PLoS One

Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation

(2013) Roberto Frau et al.   PSYCHONEUROENDOCRINOLOGY

Use of Fenofibrate During the First Trimester of Unplanned Pregnancy in a Patient with Hypertriglyceridemia

(2012) H. Sunman et al.   ANNALS OF PHARMACOTHERAPY

Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-α gene (PPARA) and schizophrenia

(2012) Marta Costa et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Sex effects on neurodevelopmental outcomes of innate immune activation during prenatal and neonatal life

(2012) Shadna A. Rana et al.   HORMONES AND BEHAVIOR

Prenatal exposure to a viral mimetic alters behavioural flexibility in male, but not female, rats

(2011) Ying Zhang et al.   NEUROPHARMACOLOGY

Altered object-in-place recognition memory, prepulse inhibition, and locomotor activity in the offspring of rats exposed to a viral mimetic during pregnancy

(2011) J.G. Howland et al.   NEUROSCIENCE

Hyperlipidemia-Associated Pancreatitis in Pregnancy Managed With Fenofibrate

(2011) Amy E. Whitten et al.   OBSTETRICS AND GYNECOLOGY

Schizophrenia and Autism: Both Shared and Disorder-Specific Pathogenesis Via Perinatal Inflammation?

(2011) URS MEYER et al.   PEDIATRIC RESEARCH

Increased Synaptic Dopamine Function in Associative Regions of the Striatum in Schizophrenia

(2010) Lawrence S. Kegeles et al.   ARCHIVES OF GENERAL PSYCHIATRY

From Surface to Nuclear Receptors: The Endocannabinoid Family Extends its Assets

(2010) M. Pistis et al.   CURRENT MEDICINAL CHEMISTRY

The modulatory mechanisms of fenofibrate on human primary T cells

(2010) Shu-Meng Cheng et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A Longitudinal Examination of the Neurodevelopmental Impact of Prenatal Immune Activation in Mice Reveals Primary Defects in Dopaminergic Development Relevant to Schizophrenia

(2010) S. Vuillermot et al.   JOURNAL OF NEUROSCIENCE

Prenatal Lipopolysaccharide Reduces Social Behavior in Male Offspring

(2010) Thiago B. Kirsten et al.   NEUROIMMUNOMODULATION

Late Prenatal Immune Activation in Mice Leads to Behavioral and Neurochemical Abnormalities Relevant to the Negative Symptoms of Schizophrenia

(2010) Byron KY Bitanihirwe et al.   NEUROPSYCHOPHARMACOLOGY

Gonadal Steroid Action and Brain Sex Differentiation in the Rat

(2009) Y. Sakuma   JOURNAL OF NEUROENDOCRINOLOGY

PPARα ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-κB and AP-1 pathways

(2008) Sriram Ramanan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia

(2008) Christine Winter et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Endogenous Fatty Acid Ethanolamides Suppress Nicotine-Induced Activation of Mesolimbic Dopamine Neurons through Nuclear Receptors

(2008) M. Melis et al.   JOURNAL OF NEUROSCIENCE

Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia

(2008) E Romero et al.   MOLECULAR PSYCHIATRY

Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy

(2008) U. Meyer et al.   NEUROSCIENCE

Electrophysiological properties of dopamine neurons in the ventral tegmental area of Sardinian alcohol-preferring rats

(2008) Miriam Melis et al.   PSYCHOPHARMACOLOGY