Estimating the success of enzyme bioprospecting through metagenomics: current status and future trends

An Enzyme Cascade Synthesis of ε-Caprolactone and its Oligomers

(2015) Sandy Schmidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel salt-tolerant chitobiosidase discovered by genetic screening of a metagenomic library derived from chitin-amended agricultural soil

(2015) Mariana Silvia Cretoiu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enzyme fusion for whole-cell biotransformation of long-chain sec-alcohols into esters

(2015) Eun-Yeong Jeon et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications

(2015) Fabian Steffen-Munsberg et al.   BIOTECHNOLOGY ADVANCES

A new generation of versatile chromogenic substrates for high-throughput analysis of biomass-degrading enzymes

(2015) Stjepan Krešimir Kračun et al.   Biotechnology for Biofuels

Scaling-Up of “Smart Cosubstrate” 1,4-Butanediol Promoted Asymmetric Reduction of Ethyl-4,4,4-trifluoroacetoacetate in Organic Media

(2015) Ralf Zuhse et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Identification and Characterization of a Cellulase-Encoding Gene from the Buffalo Rumen Metagenomic Library

(2015) Nhung Hong NGUYEN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Expanding the Halohydrin Dehalogenase Enzyme Family: Identification of Novel Enzymes by Database Mining

(2014) Marcus Schallmey et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Polysaccharide Utilization Locus from an Uncultured Bacteroidetes Phylotype Suggests Ecological Adaptation and Substrate Versatility

(2014) A. K. Mackenzie et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Alternative hosts for functional (meta)genome analysis

(2014) Wolfgang Liebl et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metataxonomic profiling and prediction of functional behaviour of wheat straw degrading microbial consortia

(2014) Diego Jiménez et al.   Biotechnology for Biofuels

Discovery and characterization of ionic liquid-tolerant thermophilic cellulases from a switchgrass-adapted microbial community

(2014) John M Gladden et al.   Biotechnology for Biofuels

A genomic survey of proteases in Aspergilli

(2014) Sebnem Budak et al.   BMC GENOMICS

Pipelines for New Chemicals: a strategy to create new value chains and stimulate innovation-based economic revival in Southern European countries

(2014) Kenneth Timmis et al.   ENVIRONMENTAL MICROBIOLOGY

Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats

(2014) María Alcaide et al.   ENVIRONMENTAL MICROBIOLOGY

Halorhabdus tiamatea:proteogenomics and glycosidase activity measurements identify the first cultivated euryarchaeon from a deep-sea anoxic brine lake as potential polysaccharide degrader

(2014) Johannes Werner et al.   ENVIRONMENTAL MICROBIOLOGY

Identification and characterization of an unusual glycosyltransferase-like enzyme with β-galactosidase activity from a soil metagenomic library

(2014) Si-di Wang et al.   ENZYME AND MICROBIAL TECHNOLOGY

Enzyme Promiscuity: Engine of Evolutionary Innovation

(2014) Chetanya Pandya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Special Issue dedicated to Karl-Erich Jaeger on the occasion of his 60th birthday

(2014) Thomas Drepper et al.   JOURNAL OF BIOTECHNOLOGY

Discovery of novel enzymes with industrial potential from a cold and alkaline environment by a combination of functional metagenomics and culturing

(2014) Jan Vester et al.   Microbial Cell Factories

Uniting the classification of cultured and uncultured bacteria and archaea using 16S rRNA gene sequences

(2014) Pablo Yarza et al.   NATURE REVIEWS MICROBIOLOGY

A High-Throughput Colorimetric Screening Assay for Terpene Synthase Activity Based on Substrate Consumption

(2014) Maiko Furubayashi et al.   PLoS One

Protein Variants Form a System of Networks: Microdiversity of IMP Metallo-Beta-Lactamases

(2014) Michael Widmann et al.   PLoS One

Multisubstrate Isotope Labeling and Metagenomic Analysis of Active Soil Bacterial Communities

(2014) Y. Verastegui et al.   mBio

AromaDeg, a novel database for phylogenomics of aerobic bacterial degradation of aromatics

(2014) Márcia Duarte et al.   Database-The Journal of Biological Databases and Curation

Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains

(2014) Nikos C. Kyrpides et al.   PLOS BIOLOGY

Minireactor-based high-throughput temperature profiling for the optimization of microbial and enzymatic processes

(2014) Martin Kunze et al.   Journal of Biological Engineering

Compositional profile of α / β-hydrolase fold proteins in mangrove soil metagenomes: prevalence of epoxide hydrolases and haloalkane dehalogenases in oil-contaminated sites

(2014) Diego Javier Jiménez et al.   Microbial Biotechnology

Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening

(2014) María-Eugenia Guazzaroni et al.   Microbial Biotechnology

Biochemical studies on a versatile esterase that is most catalytically active with polyaromatic esters

(2014) Mónica Martínez-Martínez et al.   Microbial Biotechnology

Nitrilase Activity Screening on Structurally Diverse Substrates: Providing Biocatalytic Tools for Organic Synthesis

(2013) Carine Vergne-Vaxelaire et al.   ADVANCED SYNTHESIS & CATALYSIS

New Glycosidase Substrates for Droplet-Based Microfluidic Screening

(2013) Majdi Najah et al.   ANALYTICAL CHEMISTRY

Protein Engineering from “Scratch” Is Maturing

(2013) Matthias Höhne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical Diversity of Carboxyl Esterases and Lipases from Lake Arreo (Spain): a Metagenomic Approach

(2013) Mónica Martínez-Martínez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metagenomic technology and genome mining: emerging areas for exploring novel nitrilases

(2013) Jin-Song Gong et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Ultra-high throughput detection of single cell β-galactosidase activity in droplets using micro-optical lens array

(2013) Jiseok Lim et al.   APPLIED PHYSICS LETTERS

Single residues dictate the co-evolution of dual esterases: MCP hydrolases from the α/β hydrolase family

(2013) María Alcaide et al.   BIOCHEMICAL JOURNAL

Convenient microtiter plate-based, oxygen-independent activity assays for flavin-dependent oxidoreductases based on different redox dyes

(2013) Dagmar Brugger et al.   Biotechnology Journal

Protein structure based prediction of catalytic residues

(2013) J Eduardo Fajardo et al.   BMC BIOINFORMATICS

Fungal genomes mining to discover novel sterol esterases and lipases as catalysts

(2013) Jorge Barriuso et al.   BMC GENOMICS

Whole-cell biocatalysis for selective and productive C–O functional group introduction and modification

(2013) Manfred Schrewe et al.   CHEMICAL SOCIETY REVIEWS

Biocatalysis enters a new era

(2013) Nicholas J Turner et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Protein engineering of enzymes for process applications

(2013) John M Woodley   CURRENT OPINION IN CHEMICAL BIOLOGY

Alcohol dehydrogenase stabilization by additives under industrially relevant reaction conditions

(2013) Dominik Spickermann et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Droplet-based microfluidic platform for heterogeneous enzymatic assays

(2013) Chieh Chang et al.   LAB ON A CHIP

Revealing the hidden functional diversity of an enzyme family

(2013) Karine Bastard et al.   Nature Chemical Biology

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Soil Bacterial Community Shifts after Chitin Enrichment: An Integrative Metagenomic Approach

(2013) Samuel Jacquiod et al.   PLoS One

Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica

(2013) Michael Kube et al.   Nature Communications

Heterologous viral expression systems in fosmid vectors increase the functional analysis potential of metagenomic libraries

(2013) L. Terrón-González et al.   Scientific Reports

The COMBREX Project: Design, Methodology, and Initial Results

(2013) Brian P. Anton et al.   PLOS BIOLOGY

Coupled high-throughput functional screening and next generation sequencing for identification of plant polymer decomposing enzymes in metagenomic libraries

(2013) Mari Nyyssönen et al.   Frontiers in Microbiology

Is metagenomics resolving identification of functions in microbial communities?

(2013) Ludmila Chistoserdova   Microbial Biotechnology

Glycoside Hydrolases from a targeted Compost Metagenome, activity-screening and functional characterization

(2012) Michael J Dougherty et al.   BMC BIOTECHNOLOGY

Tools to kill: Genome of one of the most destructive plant pathogenic fungi Macrophomina phaseolina

(2012) Md Islam et al.   BMC GENOMICS

Probing the diverse landscape of protein flexibility and binding

(2012) Joseph A Marsh et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Searching for microbial protein over-expression in a complex matrix using automated high throughput MS-based proteomics tools

(2012) Michiel Akeroyd et al.   JOURNAL OF BIOTECHNOLOGY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

PeroxiBase: a database for large-scale evolutionary analysis of peroxidases

(2012) Nizar Fawal et al.   NUCLEIC ACIDS RESEARCH

Assessment of Metagenomic Assembly Using Simulated Next Generation Sequencing Data

(2012) Daniel R. Mende et al.   PLoS One

TREX: A Universal Tool for the Transfer and Expression of Biosynthetic Pathways in Bacteria

(2012) Anita Loeschcke et al.   ACS Synthetic Biology

Isolation of a Novel Cutinase Homolog with Polyethylene Terephthalate-Degrading Activity from Leaf-Branch Compost by Using a Metagenomic Approach

(2011) Sintawee Sulaiman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The activity level of a microbial community function can be predicted from its metatranscriptome

(2011) Damian E Helbling et al.   ISME Journal

Identification and characterization of a new true lipase isolated through metagenomic approach

(2011) Arnaldo Glogauer et al.   Microbial Cell Factories

Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen

(2011) M. Hess et al.   SCIENCE

A novel cold active esterase derived from Colombian high Andean forest soil metagenome

(2011) Diego Javier Jiménez et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

The Laccase Engineering Database: a classification and analysis system for laccases and related multicopper oxidases

(2011) Demet Sirim et al.   Database-The Journal of Biological Databases and Curation

How Many Species Are There on Earth and in the Ocean?

(2011) Camilo Mora et al.   PLOS BIOLOGY

Enzymes for the laundry industries: tapping the vast metagenomic pool of alkaline proteases

(2011) F. Niehaus et al.   Microbial Biotechnology

Design of Thermostable Beta-Propeller Phytases with Activity over a Broad Range of pHs and Their Overproduction by Pichia pastoris

(2010) J. M. Viader-Salvado et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A nitrilase from a metagenomic library acts regioselectively on aliphatic dinitriles

(2010) Sally Bayer et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Approaches for novel enzyme discovery from marine environments

(2010) Hyun Sook Lee et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metagenomic era for biocatalyst identification

(2010) Lucía Fernández-Arrojo et al.   CURRENT OPINION IN BIOTECHNOLOGY

Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes

(2010) L. Tasse et al.   GENOME RESEARCH

Interplay of heritage and habitat in the distribution of bacterial signal transduction systems

(2010) Michael Y. Galperin et al.   Molecular BioSystems

Mining bacterial genomes for novel arylesterase activity

(2010) Lijun Wang et al.   Microbial Biotechnology

A novel family VIII carboxylesterase derived from a leachate metagenome library exhibits promiscuous β-lactamase activity on nitrocefin

(2009) Konanani Rashamuse et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Isolation and Characterization of a GDSL Esterase from the Metagenome of a Marine Sponge-associated Bacteria

(2009) Yoshiko Okamura et al.   MARINE BIOTECHNOLOGY

Exploring microbial diversity for biotechnology: the way forward

(2009) Brajesh Kumar Singh   TRENDS IN BIOTECHNOLOGY

Inter-conversion of catalytic abilities in a bifunctional carboxyl/feruloyl-esterase from earthworm gut metagenome

(2009) José María Vieites et al.   Microbial Biotechnology

A Parsimony Approach to Biological Pathway Reconstruction/Inference for Genomes and Metagenomes

(2009) Yuzhen Ye et al.   PLoS Computational Biology

Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes

(2008) Lokesh P Tripathi et al.   BMC GENOMICS

Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome

(2008) Gang Li et al.   Microbial Cell Factories

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH

Novel thermophilic and thermostable lipolytic enzymes from a Thailand hot spring metagenomic library

(2007) Pacawadee Tirawongsaroj et al.   JOURNAL OF BIOTECHNOLOGY