Article
Orthopedics
Bryant A. Seamon, Steven A. Kautz, Mark G. Bowden, Craig A. Velozo
Summary: Interpreting change is an important part of clinical decision making for physical therapists. The traditional approach of minimal detectable change (MDC) assumes equal measurement error across a scale, limiting its applicability to sample characteristics. In contrast, item response theory (IRT) calculates separate estimates of measurement error and generates conditional minimal detectable change (cMDC) values, allowing for personalized interpretation of change scores and preventing misclassification.
Article
Clinical Neurology
Marta Olive-Gadea, David Cano, Marc Rodrigo-Gisbert, Marian Muchada, Estefania Montiel, Maria Baladas, Ester Sanchez-Gavilan, Carolina Paredes, Alvaro Garcia-Tornel, Marta Rubiera, Manuel Requena, Marc Ribo, Carlos A. Molina
Summary: Patient-reported outcome measures (PROMs) provide valuable information for assessing the long-term outcomes of stroke patients. This study used a mobile app to evaluate PROMs in patients with minor stroke or transient ischemic attack and found a correlation between patient-reported outcomes and clinician-assessed outcomes, although some differences were observed.
Review
Medicine, General & Internal
Alba Nicolas-Boluda, Anne Oppenheimer, Jerome Bouaziz, Arnaud Fauconnier
Summary: Patient Reported Outcome Measures (PROM) allow capturing patients' perspectives on their condition in the context of endometriosis care. Despite their extensive use in research and clinical trials, PROMs are rarely used in clinical practice. The development of digital tools can help facilitate the integration of PROMs into routine endometriosis care, improving patient-centered communication and quality of life.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
K. Thiran Jayasundera, Rebhi O. Abuzaitoun, Lilia Popova, Maria Fernanda Abalem, Chris A. Andrews, Gabrielle D. Lacy, David M. Fresco, David C. Musch
Summary: The purpose of this study is to evaluate the construct validity of the Michigan Retinal Degeneration Questionnaire (MRDQ) and the Michigan Vision-related Anxiety Questionnaire (MVAQ). The study recruited subjects with a clinical diagnosis of inherited retinal disease (IRD) and used three tests to assess construct validity. The results showed that the MRDQ and MVAQ demonstrated aspects of construct validity.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Editorial Material
Dermatology
C. C. Zouboulis, P. V. Chernyshov
Summary: The study by R. Sommer et al. published in the Journal of the European Academy of Dermatology and Venereology in 2021 focused on a specific topic in the field of dermatology.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Review
Psychiatry
Danilo Carrozzino, Chiara Patierno, Jenny Guidi, Carmen Berrocal Montiel, Jianxin Cao, Mary E. Charlson, Kaj Sparle Christensen, John Concato, Carlos De las Cuevas, Jose De Leon, Ajandek Eory, Marcelo Pio Fleck, Toshi A. Furukawa, Ralph I. Horwitz, Andrew A. Nierenberg, Chiara Rafanelli, Hongxing Wang, Thomas N. Wise, Nicoletta Sonino, Giovanni A. Fava
Summary: PROMs are self-rated scales and indices developed to improve the detection of patients' subjective experience. The psychometric model's limitations highlight the need for a more suitable framework, such as clinimetrics. Clinimetric and psychometric approaches differ in terms of characteristics related to reliability, sensitivity, validity, and clinical utility of instruments.
PSYCHOTHERAPY AND PSYCHOSOMATICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ilham Mounssif, Valentina Bentivogli, Alexandra Rendon, Davide B. Gissi, Francesco Maiani, Claudio Mazzotti, Monica Mele, Matteo Sangiorgi, Giovanni Zucchelli, Martina Stefanini
Summary: The present study aimed to investigate the impact of different periodontal surgical treatments on the quality of life and postoperative morbidity. The results revealed that periodontal surgical procedures have a low impact on patients' quality of life and a limited duration of postoperative discomfort as well as the incidence of complications.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Pediatrics
Anna Rodenbough, Cydney Opolka, Tingyu Wang, Scott Gillespie, Megan Ververis, Anne M. Fitzpatrick, Jocelyn R. Grunwell
Summary: This article examines the relationship between adverse childhood experiences (ACEs) and the health outcomes of critically ill children in the United States. The findings suggest that critically ill children have a high burden of ACEs, which negatively affects their emotional, social, and physical health.
FRONTIERS IN PEDIATRICS
(2022)
Review
Otorhinolaryngology
Jennifer Moloney, Margaret Walshe, Julie Regan
Summary: This study aimed to identify the range of PROMs commonly used in clinical trials for dysphagia following stroke and found that the SWAL-QOL and EAT-10 are commonly used PROMs. However, these tools do not directly assess the impact of 'Environmental Factors' and 'Role Functioning' on dysphagia.
Article
Medicine, General & Internal
Umile Giuseppe Longo, Sergio De Salvatore, Ilaria Piergentili, Nicolo Panattoni, Anna Marchetti, Maria Grazia De Marinis, Vincenzo Denaro
Summary: Anxiety and depressive symptoms have a negative impact on surgical outcomes in patients with rotator cuff tear undergoing surgical repair. Patients without mood disorders before rotator cuff repair are ideal candidates for surgery. This study found that anxiety and depressive symptoms significantly reduced after rotator cuff repair, leading to improvements in functionality, ability to carry out activities of daily living, perceived pain, and quality of life.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medical Informatics
Finlay J. Pearce, Samantha Cruz Rivera, Xiaoxuan Liu, Elaine Manna, Alastair K. Denniston, Melanie J. Calvert
Summary: This systematic evaluation examines the use of patient-reported outcome measures (PROMs) in clinical trials for artificial intelligence (AI) technologies. The study found that although there is an increase in the number of clinical trials for AI health technologies, the use of PROMs is still lacking. The most common clinical areas where PROMs are used include digestive system health and musculoskeletal health.
LANCET DIGITAL HEALTH
(2023)
Review
Health Care Sciences & Services
Priscilla Jia Ling Wee, Yu Heng Kwan, Dionne Hui Fang Loh, Jie Kie Phang, Troy H. Puar, Truls Ostbye, Julian Thumboo, Sungwon Yoon, Lian Leng Low
Summary: This study systematically reviewed 238 unique PROMs for patients with type 2 diabetes, categorized them based on their measurement properties, and may assist clinicians and researchers in selecting appropriate high-quality PROMs for clinical practice and research.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Biochemical Research Methods
Martin Howell, Noa Amir, Chandana Guha, Karine Manera, Allison Tong
Summary: Randomised controlled clinical trials are essential for clinical guidelines and patient care. Valid and reliable PROMs are necessary to measure patient outcomes. Mixed methods research is critical for developing PROMs.
Review
Obstetrics & Gynecology
James O. ' Carroll, Kazuo Ando, Romy Yun, Danielle Panelli, Angela Nicklin, Natasha Kennedy, Brendan Carvalho, Lindsay Blake, Jessica Coker, Debra Kaysen, Pervez Sultan
Summary: This study aimed to identify the best patient-reported outcome measure for postpartum anxiety by conducting a systematic review and evaluating the psychometric properties of instruments. Five instruments were recommended for use, but with limitations. Future research is needed to determine the optimal instrument or develop a more specific measure for maternal postpartum anxiety.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Review
Medicine, General & Internal
Zachary Blood, Anh Tran, Lauren Caleo, Robyn Saw, Mbathio Dieng, Mark Shackleton, H. Peter Soyer, Chris Arnold, Graham J. Mann, Rachael L. Morton
Summary: This systematic review identified PROMs and PREMs used in clinical quality registries for cutaneous melanoma patients, showing that they can enhance care transparency, quality assessment, and research, yet challenges such as resource burden and collection bias may limit their generalizability.
Article
Immunology
Brittany Lapin, Kevin W. Garey, Henry Wu, V Sissi, Shirley P. Huang, Pat Ray Reese, Elaine Wang, Abhishek Deshpande
Summary: In a post hoc analysis of 182 outpatients included in a phase 3 clinical trial, we demonstrated the reliability, validity, and responsiveness of a 32-item disease-specific questionnaire (Cdiff32) for patients with recurrent Clostridioides difficile infection.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Nicolas R. Thompson, Brittany R. Lapin, Michael P. Steinmetz, Edward C. Benzel, Irene L. Katzan
Summary: Linear regression, linear, and equipercentile equating methods were used to map between MDQ and PROMIS-PF and PROMIS-PI scales. Results showed that using both PROMIS-PF and PROMIS-PI together had the closest estimated means, lowest RMSE and MAE, and highest correlations for estimating MDQ total scores. Equipercentile equating using the MDQ items performed best for estimating each of PROMIS-PF and PROMIS-PI T-scores.
QUALITY OF LIFE RESEARCH
(2022)
Article
Health Care Sciences & Services
Brittany Lapin, Irene L. Katzan
Summary: This study evaluated the ability of utilizing items on a global health measure to identify patients who may require additional screening. The results showed that these items can be used as screening tools to identify patients with poor scores on additional construct-specific outcomes. By directing construct-specific assessments to applicable patients, survey burden could be reduced, leading to a more efficient and targeted use of PROMs in healthcare decision-making.
QUALITY OF LIFE RESEARCH
(2023)
Article
Medicine, General & Internal
Kevin W. Garey, Jinhee Jo, Anne J. Gonzales-Luna, Brittany Lapin, Abhishek Deshpande, Elaine Wang, Brooke Hasson, Sissi V. Pham, Shirley P. Huang, Pat Ray Reese, Henry Wu, Elizabeth Hohmann, Paul Feuerstadt, Caterina Oneto, Charles S. Berenson, Christine Lee, Barbara McGovern, Lisa vonMoltke
Summary: This secondary analysis of a phase 3 clinical trial investigated the association of SER-109 with health-related quality of life (HRQOL) in patients with recurrent Clostridioides difficile infection (CDI). The study found that SER-109 was associated with significant improvements in HRQOL compared to placebo, indicating its potential as an important treatment option for CDI patients.
Article
Behavioral Sciences
Vineet Punia, Yadi Li, Brittany Lapin, Pradeep Chandan, Christopher Newey, Stephen Hantus, Monika Dhakar, Clio Rubinos, Sahar Zafar, Adithya Sivaraju, Irene L. Katzan
Summary: The study aims to evaluate the impact of ASyS and ASMs on PROMs in stroke patients. A retrospective cohort study was conducted, including all stroke patients who underwent inpatient cEEG monitoring. The results showed that ASM use was associated with ASyS diagnosis, but there were no significant differences in PROMs based on ASyS status, ASM use at hospital discharge, or ASM status on the day of PROM completion.
EPILEPSY & BEHAVIOR
(2023)
Article
Clinical Neurology
Michael P. Phelan, Nicolas R. Thompson, Zubair Ahmed, Brittany Lapin, Belinda Udeh, Eric Anderson, Irene Katzan, Laura E. Walker
Summary: This study aimed to compare the clinical characteristics between outpatient headache clinic patients who self-report visiting the emergency department for headache and those who do not. The results showed that there were significant differences in age, race, insurance status, and area deprivation index between patients who reported emergency department utilization and those who did not. Additionally, worse patient-reported outcome measures were associated with a higher risk of emergency department utilization.
Article
Clinical Neurology
Zubair Ahmed, Ryan Honomichl, Stephen F. Thompson, Joshua M. Cohen, Andrew Schuster, Nicolas R. Thompson, Brittany Lapin, Belinda L. Udeh, Verena Ramirez Campos, Lynda J. Krasenbaum, Irene L. Katzan
Summary: This study compared the clinical and demographic characteristics of patients with chronic migraine (CM) and episodic migraine (EM) in a hospital headache clinic, and investigated the effect of migraine subtype on patient-reported outcome measures (PROM). The results showed that CM patients reported more severe headaches, poorer quality of life, and higher levels of psychological health problems compared to EM patients.
Letter
Health Care Sciences & Services
Cinthya Pena-Orbea, Brittany Lapin, Yadi Li, Kristin Englund, Catherine Heinzinger, Nancy Foldvary-Schaefer, Reena Mehra
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Clinical Neurology
Brittany Lapin, Yadi Li, Sara Davin, Mary Stilphen, Joshua K. Johnson, Edward Benzel, Ghaith Habboub, Irene L. Katzan
Summary: This study aimed to compare the performance of different stratification techniques for subgrouping patients with chronic low back pain. The results showed that all four techniques had good validity and prognostic utility, with ISS and LCA symptom clusters being the optimal methods. Future research should explore multidisciplinary treatment approaches based on these techniques for mild, moderate, and severe patients.
Article
Multidisciplinary Sciences
Helen Valsamis, Samah Abdul Baki, Jason Leung, Samer Ghosn, Brittany Lapin, Geetha Chari, Izad-Yar Rasheed, Jaehan Park, Vineet Punia, Ghinwa Masri, Dileep Nair, Ann Marie Kaniecki, Muhammad Edhi, Carl Y. Saab
Summary: This study found significant changes in brain rhythms in COVID-19 patients through quantitative and qualitative analysis of electroencephalography (EEG), especially in patients below the age of 70. These findings are important for understanding the long-term effects of COVID-19 on brain function and the utility of EEG monitoring in COVID-19 patients.
SCIENTIFIC REPORTS
(2023)
Article
Neurosciences
Shilpa C. Rao, Yadi Li, Brittany Lapin, Sreya Pattipati, Kamalini Ghosh Galvelis, Anna Naito, Nicolas Gutierrez, Thiago Peixoto Leal, Amira Salim, Philippe A. Salles, Maria De Leon, Ignacio F. Mata
Summary: Parkinson's disease (PD) is an age-related neurological disorder that shows differences in risk, progression, and severity between men and women. This study aimed to identify women-specific health experiences associated with PD severity by developing and distributing a women-specific questionnaire and creating multivariable models. The results found significant associations between major depressive disorder, perinatal depression, natural childbirth, LRRK2 genotype, B12 deficiency, total hysterectomy, and increased PD severity. This study provides important insights into the etiology of PD and highlights the role of sex-specific experiences.
NPJ PARKINSONS DISEASE
(2023)
Review
Health Care Sciences & Services
Brittany Lapin, Matthew L. Cohen, Nadia Corsini, Alyssa Lanzi, Sarah C. Smith, Antonia V. Bennett, Nancy Mayo, Rebecca Mercieca-Bebber, Sandra A. Mitchell, Claudia Rutherford, Jessica Roydhouse
Summary: This study aims to explore methodological guidelines for proxy reporting in adult populations and develop relevant considerations. Through a review of literature and clinical assessment measures, it was found that there is inconsistency in the definition of proxy reporting in adult populations and a lack of considerations for proxy selection and data collection, analysis, and reporting. Therefore, a checklist of considerations for proxy reporting is provided to assist researchers and clinicians in using proxy reporting in research and clinical care.
JOURNAL OF PATIENT-REPORTED OUTCOMES
(2023)
Article
Health Care Sciences & Services
Nicolas R. Thompson, Brittany R. Lapin, Irene L. Katzan
Summary: This study aimed to evaluate and compare estimated utilities based on PROPr and PROMIS-GH in adult stroke survivors. The results showed that all three PROMIS-based utilities were associated with measures of stroke disability and severity, but the distributions of utilities were very different. Therefore, different utility measurement methods need to be considered when assessing health states.
MEDICAL DECISION MAKING
(2023)
Editorial Material
Clinical Neurology
A. B. Sullivan, S. A. Davin, B. Lapin, A. T. Schuster, R. A. Dweik, K. F. Murray, S. J. Rehm, A. G. Machado
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2023)
Meeting Abstract
Economics
B. Lapin, K. Garey, H. Wu, S. Pham, S. Huang, P. R. Reese, E. Wang, B. McGovern, A. Deshpande