Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

出版年份 2018 全文链接

标题

作者

关键词

CRISPR-Cas, genome editing, cryo-EM, protein-RNA-DNA complex, single-molecule FRET

出版物

Volume 175, Issue 7, Pages 1856-1871.e21

出版商

Elsevier BV

发表日期

2018-11-30

DOI

10.1016/j.cell.2018.10.045

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