The anti-inflammatory and anti-fibrotic effects of tadalafil in thioacetamide-induced liver fibrosis in rats

Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice

(2018) Mardi M. Algandaby   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

The effect of tadalafil therapy on kidney damage caused by sepsis in a polymicrobial septic model induced in rats: a biochemical and histopathological study

(2017) Erdal Benli et al.   International Braz J Urol

Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice

(2017) Fadi N. Salloum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

Tadalafil reduces airway hyperactivity and protects against lung and respiratory airways dysfunction in a rat model of silicosis

(2016) Rania R. Abdelaziz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Beneficial Effects of Silymarin After the Discontinuation of CCl4-Induced Liver Fibrosis

(2016) Simona Clichici et al.   JOURNAL OF MEDICINAL FOOD

The effects of tadalafil and pentoxifylline on apoptosis and nitric oxide synthase in liver ischemia/reperfusion injury

(2016) Sibel Bektas et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer

(2015) Anindita Das et al.   PHARMACOLOGY & THERAPEUTICS

Free Radical-Scavenging, Anti-Inflammatory/Anti-Fibrotic and Hepatoprotective Actions of Taurine and Silymarin against CCl4 Induced Rat Liver Damage

(2015) Ashraf M. Abdel-Moneim et al.   PLoS One

Silymarin Reduces Profibrogenic Cytokines and Reverses Hepatic Fibrosis in Chronic Murine Schistosomiasis

(2014) Hílton Antônio Mata-Santos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protective Effects of Diallyl Sulfide against Thioacetamide-Induced Toxicity: A Possible Role of Cytochrome P450 2E1

(2014) Nam Hee Kim et al.   Biomolecules & Therapeutics

Effect of bone marrow-derived mesenchymal stem cells on hepatic fibrosis in a thioacetamide-induced cirrhotic rat model

(2014) Yoon Ok Jang et al.   BMC GASTROENTEROLOGY

Modulation of thioacetamide-induced hepatic inflammations, angiogenesis and fibrosis by andrographolide in mice

(2014) Tzung-Yan Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protective mechanisms of medicinal plants targeting hepatic stellate cell activation and extracellular matrix deposition in liver fibrosis

(2014) Florent Duval et al.   Chinese Medicine

Modulation of thioacetamide-induced liver fibrosis/cirrhosis by sildenafil treatment

(2013) Eman Said et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Clinical Characteristics and Time Trends in Etiology of Hepatocellular Cancer in Germany

(2013) Kerstin Schütte et al.   DIGESTION

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice

(2013) Ling Yang et al.   HEPATOLOGY

Sildenafil for Erectile Dysfunction in the Middle East: Observational Analysis of Patients with Diabetes and/or Hypertension Treated in the Clinical Practice Setting

(2013) AI El-Sakka et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Preventive effect of phosphodiesterase 5 inhibitor Tadalafil on experimental post-pyelonephritic renal injury in rats

(2013) Chun-Yan Zhu et al.   JOURNAL OF SURGICAL RESEARCH

Transforming Growth Factor β Neutralization Ameliorates Pre-Existing Hepatic Fibrosis and Reduces Cholangiocarcinoma in Thioacetamide-Treated Rats

(2013) Hong Ling et al.   PLoS One

Effects of Tadalafil on Hemorrhagic Cystitis and Testicular Dysfunction Induced by Cyclophosphamide in Rats

(2013) Semra Yigitaslan et al.   UROLOGIA INTERNATIONALIS

Coffee attenuates fibrosis by decreasing the expression of TGF-β and CTGF in a murine model of liver damage

(2012) Jonathan Arauz et al.   JOURNAL OF APPLIED TOXICOLOGY

Silymarin potentiates the anti-inflammatory effects of Celecoxib on chemically induced osteoarthritis in rats

(2012) Z. Ashkavand et al.   PHYTOMEDICINE

Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice

(2012) Amit Varma et al.   PLoS One

Mechanism of action of phosphodiesterase type 5 inhibition in metabolic syndrome-associated prostate alterations: An experimental study in the rabbit

(2012) Annamaria Morelli et al.   PROSTATE

Biochemical and immunological basis of silymarin effect, a milk thistle (Silybum marianum) against ethanol-induced oxidative damage

(2012) Subir Kumar Das et al.   TOXICOLOGY MECHANISMS AND METHODS

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release

(2011) FAC Rocha et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

(2011) Thérèse Keravis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Thioacetamide Intoxication Triggers Transcriptional Up-Regulation but Enzyme Inactivation of UDP-Glucuronosyltransferases

(2011) H. Hao et al.   DRUG METABOLISM AND DISPOSITION

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats

(2011) S. Abramovitch et al.   GUT

Hepatoprotection of silymarin against thioacetamide-induced chronic liver fibrosis

(2011) I-Shu Chen et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Comparison of imatinib, nilotinib and silymarin in the treatment of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis

(2011) Mohamed E. Shaker et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Current status of novel antifibrotic therapies in patients with chronic liver disease

(2011) Michal Cohen-Naftaly et al.   Therapeutic Advances in Gastroenterology

Tadalafil for the treatment of pulmonary arterial hypertension

(2011) James R Klinger   Expert Review of Respiratory Medicine

Treatment of Peyronie's disease with PDE5 inhibitors: an antifibrotic strategy

(2010) Nestor F. Gonzalez-Cadavid et al.   Nature Reviews Urology

Identification of hepatoprotective flavonolignans from silymarin

(2010) S. J. Polyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction

(2010) A. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The toxic effect of thioacetamide on rat liver in vitro

(2010) Pavla Staňková et al.   TOXICOLOGY IN VITRO

PDE5 Inhibitors: In Vitro and In Vivo Pharmacological Profile

(2009) D. Kouvelas et al.   CURRENT PHARMACEUTICAL DESIGN

Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage

(2009) E. Shaker et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats

(2009) Ming-Kuei Tsai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis

(2008) Tung-Ming Leung et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

(2008) Giovanni Tarantino et al.   Journal of Translational Medicine