期刊
BRAIN INJURY
卷 33, 期 4, 页码 529-533出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/02699052.2019.1566832
关键词
Behavioral scale; Coma Recovery Scale-Revised; consciousness; unresponsive wakefulness syndrome; minimally conscious state
资金
- National Natural Science Foundation of China [81471100]
- National High Technology Research and Development Program of China (863 Program) [2015AA020514]
- Hangzhou Normal University [PD11002010002016]
- Research Fund for International Young Scientists of the National Natural Science Foundation of China [811247008]
- Medical Science and Technology Projects in Zhejiang Province [2013KYB213, 2015KYA181]
- College students in Zhejiang Province Science and Technology Innovation Activities plan [2017R423055]
Primary Objective: This study aims to validate the Chinese version of the Coma Recovery Scale-Revised (CRS-R). Methods: One hundred sixty-nine patients were assessed with both the CRS-R and the Glasgow Coma Scale (GCS), diagnosed as being in unresponsive wakefulness syndrome (UWS, formerly known as vegetative state), minimally conscious state (MCS), or emergence from MCS (EMCS). A subgroup of 50 patients has been assessed twice by the same rater, within 24 h. Patient outcome was documented six months after assessment. Results: The internal consistency for the CRS-R total score was excellent (Cronbach's alpha = 0.84). Good test-retest reliability was obtained for CRS-R total score and subscale scores (intra-class correlation coefficient [ICC] = 0.87 and ICC = 0.66-0.84, respectively). Inter-rater reliability was high (ICC = 0.719; p < 0.01). Concurrent validity was good between CRS-R total scale and GCS total scale. Diagnostic validity was excellent compared with GCS (emerged from UWS: 24%; emerged from MCS: 28%). When considering patient outcome, diagnostic validity was good. In addition, false-positive rates have been detected for both diagnoses. Conclusion: The Chinese version of the CRS-R is a reliable and sensitive tool and can discriminate patients in UWS, MCS, and EMCS successfully.
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