Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children

Development of quantitative suspension array assays for six immunoglobulin isotypes and subclasses to multiple Plasmodium falciparum antigens

(2018) Marta Vidal et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies

(2018) Itziar Ubillos et al.   MALARIA JOURNAL

Development of a high-throughput flexible quantitative suspension array assay for IgG against multiple Plasmodium falciparum antigens

(2018) Itziar Ubillos et al.   MALARIA JOURNAL

Analysis of factors affecting the variability of a quantitative suspension bead array assay measuring IgG to multiple Plasmodium antigens

(2018) Itziar Ubillos et al.   PLoS One

Antibody responses to α-Gal in African children vary with age and site and are associated with malaria protection

(2018) Ruth Aguilar et al.   Scientific Reports

The establishment of a WHO Reference Reagent for anti-malaria (Plasmodium falciparum) human serum

(2017) Donna Bryan et al.   MALARIA JOURNAL

Vaccines to Accelerate Malaria Elimination and Eventual Eradication

(2017) Julie Healer et al.   Cold Spring Harbor Perspectives in Medicine

Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study

(2017) Oliver J Brady et al.   Lancet Global Health

Chronic Exposure to Malaria Is Associated with Inhibitory and Activation Markers on Atypical Memory B Cells and Marginal Zone-Like B Cells

(2017) Itziar Ubillos et al.   Frontiers in Immunology

RTS,S/AS01 Malaria Vaccine Efficacy is Not Modified by Seasonal Precipitation: Results from a Phase 3 Randomized Controlled Trial in Malawi

(2017) Larry Han et al.   Scientific Reports

Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsonophagocytosis

(2017) Sidhartha Chaudhury et al.   Scientific Reports

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

(2016) Jason A. Regules et al.   JOURNAL OF INFECTIOUS DISEASES

The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

(2016) Sidhartha Chaudhury et al.   MALARIA JOURNAL

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

(2016) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

RTS,S Malaria Vaccine and Increased Mortality in Girls

(2016) Sabra L. Klein et al.   mBio

Antimalarial mass drug administration: ethical considerations

(2016) Phaik Yeong Cheah et al.   International Health

CD14hiCD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so

(2015) Jingling Zhou et al.   BMC Medicine

Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance

(2015) Lorenz von Seidlein et al.   Expert Review of Anti-Infective Therapy

Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria

(2015) Michelle J. Boyle et al.   IMMUNITY

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

(2015) Michael T White et al.   LANCET INFECTIOUS DISEASES

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants

(2015) Anthony Ajua et al.   MALARIA JOURNAL

Opsonic phagocytosis of Plasmodium falciparummerozoites: mechanism in human immunity and a correlate of protection against malaria

(2014) Faith HA Osier et al.   BMC Medicine

Pregnancy and Malaria Exposure Are Associated with Changes in the B Cell Pool and in Plasma Eotaxin Levels

(2014) Pilar Requena et al.   JOURNAL OF IMMUNOLOGY

Avidity of Anti-Circumsporozoite Antibodies following Vaccination with RTS,S/AS01E in Young Children

(2014) Ally Olotu et al.   PLoS One

Duration of vaccine efficacy against malaria: 5th year of follow-up in children vaccinated with RTS,S/AS02 in Mozambique

(2014) Joseph J. Campo et al.   VACCINE

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

(2014)   PLOS MEDICINE

Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure

(2013) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion

(2012) J. Illingworth et al.   JOURNAL OF IMMUNOLOGY

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Malaria elimination: surveillance and response

(2012) Daniel J Bridges et al.   Pathogens and Global Health

Age-Dependent IgG Subclass Responses to Plasmodium falciparum EBA-175 Are Differentially Associated with Incidence of Malaria in Mozambican Children

(2011) Carlota Dobaño et al.   Clinical and Vaccine Immunology

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance

(2009) Nicholas J White et al.   MALARIA JOURNAL

Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants

(2008) Salim Abdulla et al.   NEW ENGLAND JOURNAL OF MEDICINE