Article
Medicine, General & Internal
Rosemary Brown, Jim Lewsey, Sarah Wild, Jennifer Logue, Paul Welsh
Summary: This study found that non-achievement of lipid and statin adherence targets in myocardial infarction survivors is associated with increased risks of all-cause and cardiovascular disease mortality, but not with recurrent myocardial infarctions. Further research is needed to optimize their use in clinical practice to improve outcomes.
Article
Medicine, General & Internal
Temur Mamadjanov, Konstantinos Volaklis, Margit Heier, Dennis Freuer, Ute Amann, Annette Peters, B. Kuch, Christian Thilo, Jakob Linseisen, Christa Meisinger
Summary: The study found a significant association between admission blood glucose levels and 28-day mortality in patients aged 65-74 with AMI, but not in those aged 75-84. However, higher admission blood glucose was linked to major cardiac complications in both age groups.
Article
Cardiac & Cardiovascular Systems
Francisco Jose de Abajo, Sara Rodriguez-Martin, Diana Barreira, Antonio Rodriguez-Miguel, Encarnacion Fernandez-Anton, Miguel Gil, Alberto Garcia-Lledo
Summary: The study suggests a moderate protective effect of influenza vaccination on AMI in the general population, primarily in primary prevention. The reduced risk of AMI was observed shortly after vaccination and persisted over time, with no significant association found with pneumococcal vaccine.
Article
Oncology
S. M. Evans, K. Ivanova, R. Rome, D. Cossio, Chc Pilgrim, J. Zalcberg, Y. Antill, L. Blake, A. Du Guesclin, A. Garrett, D. Giffard, N. Golobic, D. Moir, S. Parikh, A. Parisi, K. Sanday, C. Shadbolt, M. Smith, L. Te Marvelde, K. Williams
Summary: In this paper, the completeness of stage information for endometrial cancer in Australian cancer registries is described, and a set of rules for calculating stage using available data is developed and validated.
Article
Medicine, General & Internal
Moujie Liu, Zhi Du, Yingxian Sun
Summary: This study investigated the prognostic significance of first-degree atrioventricular block (AVB) in Asian populations. The results showed that first-degree AVB is an independent risk factor for adverse events and can be used to predict the risk of cardiovascular disease and mortality.
Article
Cardiac & Cardiovascular Systems
Rachel Bedenis Forster, Camilla Kjellstadli, Tor Age Myklebust, Grace Egeland, Gerhard Sulo, Tone Bjorge, Kaare Harald Bonaa, Petur Benedikt Juliusson, Rune Kvale
Summary: This study examined the use of invasive treatment and mortality after acute myocardial infarction (AMI) in prostate cancer (PCa) patients. The results showed that except for patients with metastatic PCa experiencing an ST-segment elevation AMI, the rates of invasive treatment and 30-day mortality were similar between PCa patients and the general AMI population.
Article
Cardiac & Cardiovascular Systems
Marios Rossides, Susanna Kullberg, Johan Grunewald, Anders Eklund, Daniela Di Giuseppe, Johan Askling, Elizabeth Arkema
Summary: A small increased risk of acute myocardial infarction was identified in individuals with sarcoidosis, especially those who received immunosuppressant treatment. Early diagnostic or preventive interventions may be beneficial for these patients.
RESPIRATORY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jeppe K. Petersen, Abdulrahman N. Shams-Eldin, Emil L. Fosbol, Rasmus Rorth, Rikke Sorensen, Reza Jabbari, Thomas Engstrom, Lene Holmvang, Frants Pedersen, Amna Alhakak, Johanna Kroll, Christian Torp-Pedersen, Lars Kober, Jawad H. Butt
Summary: Employment status prior to acute myocardial infarction is associated with long-term risk of mortality and recurrent MI. Patients who were not part of the workforce had a higher risk of death and new heart attacks following discharge compared to those who were part of the workforce.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Soren Korsgaard, Christian Fynbo Christiansen, Morten Schmidt, Henrik Toft Sorensen
Summary: Analysis of the Danish National Patient Registry data showed that the proportion of recurrent myocardial infarctions identified depended on the length of the look-back period, with most recurrent MIs being identified with a 24-year look-back period. Including recurrent MIs in a planned incident MI cohort due to shorter look-back periods may lead to overestimation of risk.
CLINICAL EPIDEMIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Johanne Silvain, Michel Zeitouni, Valeria Paradies, Huili L. Zheng, Gjin Ndrepepa, Claudio Cavallini, Dimitri N. Feldman, Samin K. Sharma, Julinda Mehilli, Sebastiano Gili, Emanuele Barbato, Giuseppe Tarantini, Sze Y. Ooi, Clemens von Birgelen, Allan S. Jaffe, Kristian Thygesen, Gilles Montalescot, Heerajnarain Bulluck, Derek J. Hausenloy
Summary: The prognostic importance of cardiac procedural myocardial injury and myocardial infarction (MI) in chronic coronary syndrome (CCS) patients undergoing elective percutaneous coronary intervention (PCI) is still debated. Post-PCI cTn elevation of >= 5 x 99th percentile URL used to define Type 4a MI is associated with increased 1-year mortality in CCS patients with normal baseline cTn levels.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Francois Schiele, Chris P. Gale, Tabassome Simon, Keith A. A. Fox, Hector Bueno, Maddalena Lettino, Marco Tubaro, Etienne Puymirat, Jean Ferrieres, Fiona Ecarnot, Nicolas Danchin, Nicolas Meneveau
Summary: This study estimated the 2020 European Society of Cardiology-Acute Cardio Vascular Care (ESC-ACVC) quality indicators for the management of acute myocardial infarction using data from three existing French nationwide registries. The assessment showed that most of the 2020 QI can be measured from existing registries and were associated with centre benchmarking. Both composite QIs were inversely associated with one-year mortality.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2021)
Review
Medicine, General & Internal
Kevin Emery Boczar, Sheojung Shin, Kathryn A. Bezzina, Aishwarya Geejo, Alexander Liam Pearson, Saba Shahab, Christophe A. Fehlmann, Sarah Visintini, Rob Beanlands, George A. Wells
Summary: This systematic review aims to compare the efficacy of anti-inflammatory agents on cardiovascular outcomes in patients with known cardiovascular disease. Randomized controlled trials will be included in the analysis, and network meta-analysis will be conducted to compare treatment effects. Quality assessment will also be performed.
Article
Medicine, General & Internal
Tianyi Li, Junduo Wu, Jia Liu, Wei Sun, Chao Qi, Bin Liu, George A. Wells, Junnan Wang
Summary: The AMINoC study aims to provide real-world knowledge on characteristics, clinical care, and outcomes of AMI patients in Northeastern China. It is a prospective, multicenter cohort study involving 20 hospitals in nine districts throughout Jilin Province. The findings will be disseminated through peer-reviewed journals and medical conferences after approval by the ethics committee.
Article
Medicine, General & Internal
Hongwu Li, Jingyi Chen, Xinyue Xing, Danfei Lou
Summary: This study examined the association between lactate level or lactate clearance at different time points and in-hospital mortality in critically ill patients with acute myocardial infarction (AMI). The results showed that elevated lactate level was associated with increased risk of in-hospital mortality, while increased lactate clearance was correlated with decreased risk of in-hospital mortality.
Article
Medicine, General & Internal
Cuiping Wang, Lin Zhou, Yi Liang, Peijing Liu, Wei Yuan
Summary: This study evaluated the interaction between ST-elevation myocardial infarction (STEMI), ageing, and sex in relation to major adverse cardiovascular events (MACE) among Chinese adults. The results showed that female patients with STEMI had a 2.7 times higher risk of MACE compared to male patients without STEMI. Older patients with STEMI had a 3.3 times higher risk of MACE compared to younger patients without STEMI. The study also suggested a positive additive interaction between STEMI and age, as well as between STEMI and sex.
Article
Cardiac & Cardiovascular Systems
Flemming Javier Olsen, Caroline Lokke Bjerregaard, Kristoffer Grundtvig Skaarup, Mats Christian Hojbjerg Lassen, Niklas Dyrby Johansen, Daniel Modin, Gorm Boje Jensen, Peter Schnohr, Peter Sogaard, Gunnar Gislason, Jesper Hastrup Svendsen, Rasmus Mogelvang, Tor Biering-Sorensen
Summary: Different event timing modalities have an impact on myocardial work indices, with visual assessment yielding lower global work index (GWI) values compared with Doppler-based methods.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Sidsel Marie Bernt Jorgensen, Thomas Alexander Gerds, Nina Fons Johnsen, Gunnar Gislason, Mohamad El-Chouli, Stig Brondum, Thomas Maribo, Maria Kristiansen
Summary: Returning to work and maintaining employment after cardiovascular disease is crucial for working-age individuals. Individuals with heart failure have the highest probability of not returning to work, highlighting the need for effective vocational rehabilitation strategies in comprehensive cardiac rehabilitation programs.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Substance Abuse
Alan Manivannan, Morten Schou, Kevin M. Monahan, Robert Helm, Darae Ko, Emil Fosbol, Lars Kober, Finn Gustafsson, Gunnar H. Gislason, Christian Torp-Pedersen, Charlotte Andersson
Summary: Alcoholic cardiomyopathy (ACM) is associated with poor outcomes, but the high mortality is not driven by atrial fibrillation. Oral anticoagulation in ACM has similar stroke and bleeding risks as in dilated cardiomyopathy.
ALCOHOL AND ALCOHOLISM
(2023)
Article
Cardiac & Cardiovascular Systems
Jacob Christensen, Filip Soeskov Davidovski, Kristoffer Grundtvig Skaarup, Mats Christian Hojbjerg Lassen, Alia Lassen, Alia Alhakak, Morten Sengelov, Anne Bjerg Nielsen, Niklas Dyrby Johansen, Henning Bundgaard, Christian Hassager, Reza Jabbari, Jorn Carlsen, Ole Kirk, Ole Peter Kristiansen, Olav Wendelboe Nielsen, Charlotte Suppli Ulrik, Pradeesh Sivapalan, Gunnar Gislason, Kasper Iversen, Jens Ulrik Staehr Jensen, Morten Schou, Anders Hviid, Tyra Grove Krause, Tor Biering-Sorensen
Summary: This study investigated whether the prognostic values of echocardiographic parameters changed with updates in treatment guidelines and the emergence of novel SARS-CoV-2 variants. The results showed that patients hospitalized during the second wave had worse left ventricular function, and reduced global longitudinal strain was associated with COVID-19-related mortality independently of wave, treatment, and SARS-CoV-2 variant.
Article
Cardiac & Cardiovascular Systems
Hanna Ratcovich, Golnaz Sadjadieh, Jesper J. Linde, Francis R. Joshi, Henning Kelbaek, Klaus F. Kofoed, Lars Kober, Peter Riis Hansen, Christian Torp-Pedersen, Hanne Elming, Gunnar Hilmar Gislason, Dan Eik Hofsten, Thomas Engstrom, Lene Holmvang
Summary: This study investigated the diagnostic accuracy of cCTA and the impact of early ICA on long-term clinical outcomes in elderly patients with NSTEACS. The study found that cCTA had a high accuracy in ruling out significant CAD in patients aged ≥75 years, but early ICA did not significantly improve long-term clinical outcomes.
Article
Cardiac & Cardiovascular Systems
Hannah K. Wood-Kurland, Matthew Phelps, Jens Jakob Thune, Berit Philbert, Charlotte Ellen Larroude, Morten Schou, Morten Lock Hansen, Gunnar H. Gislason, Casper N. Bang
Summary: This study aimed to determine the impact of two nationwide lockdowns in Denmark on the implantation rate of cardiac implantable electronic devices (CIEDs). The study found that there were modest changes in CIED implantations during the lockdowns, with a decrease of 15.5% during the first lockdown and 5.1% during the second lockdown.
HEART LUNG AND CIRCULATION
(2023)
Article
Cardiac & Cardiovascular Systems
Jarl E. Strange, Caroline Sindet-Pedersen, Anders Holt, Mikkel P. Andersen, Christian Torp-Pedersen, Lars Kober, Gunnar H. Gislason, Jonas B. Olesen, Emil L. Fosbol
Summary: This study investigated the incidence and factors associated with nursing home admission (NHA) following transcatheter aortic valve replacement (TAVR) compared with the general population, and found that TAVR was not associated with an increased incidence of NHA.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Dea Haagensen Kofod, Nicholas Carlson, Ellen Freese Ballegaard, Thomas Peter Almdal, Christian Torp-Pedersen, Gunnar Gislason, Jesper Hastrup Svendsen, Bo Feldt-Rasmussen, Mads Hornum
Summary: This study investigated the risk of cardiovascular mortality in patients with advanced chronic kidney disease (CKD). The results showed that diabetes, albuminuria, and anemia were significant risk factors for cardiovascular mortality, while the predictive value of LDL-cholesterol for cardiovascular mortality in advanced CKD may be limited.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Endocrinology & Metabolism
Pratik Pokharel, Jamie W. Bellinge, Frederik Dalgaard, Kevin Murray, Marc Sim, Bu B. Yeap, Emma Connolly, Lauren C. Blekkenhorst, Catherine P. Bondonno, Joshua R. Lewis, Gunnar Gislason, Anne Tjonneland, Kim Overvad, Jonathan M. Hodgson, Carl Schultz, Nicola P. Bondonno
Summary: Observational studies have shown a lower risk of type 2 diabetes with higher vitamin K-1 intake. This study found that higher intake of foods rich in vitamin K-1 was associated with a lower risk of diabetes. This association was present in all subgroups at higher risk, indicating that more cases of diabetes could be prevented.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Cardiac & Cardiovascular Systems
Anders Holt, Jarl E. Strange, Nina Nouhravesh, Sebastian Kinnberg Nielsen, Mariam Elmegaard Malik, Anne -Marie Schjerning, Lars Kober, Christian Torp-Pedersen, Gunnar H. Gislason, Patricia McGettigan, Morten Schou, Morten Lamberts
Summary: This study found an association between short-term use of NSAIDs and an increased risk of first-time hospitalization for heart failure in patients with type 2 diabetes. Patients in subgroups with advanced age, elevated HbA1c levels, and new users of NSAIDs were particularly susceptible.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Critical Care Medicine
Deepthi Rajan, Rodrigue Garcia, Carlo A. Barcella, Jesper Svane, Peder E. Warming, Reza Jabbari, Gunnar H. Gislason, Christian Torp-Pedersen, Fredrik Folke, Jacob Tfelt-Hansen
Summary: There is no significant difference in the management and survival rates after out-of-hospital cardiac arrest between immigrants and non-immigrants in Denmark.
Article
Cardiac & Cardiovascular Systems
Nina Fons Johnsen, Sidsel Normann Jensen, Karl Bang Christensen, Susanne S. Pedersen, Charlotte Helmark, Ann-Dorthe Zwisler, Gunnar H. Gislason
Summary: This study demonstrates that the combination of WHO-5, ASS-2, and MDI-2 can be used as an alternative to the HADS questionnaire in screening anxiety and depression in cardiac patients. Crosswalks (translation tables) were generated to facilitate clinical practice.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Rehabilitation
Sidsel Marie Bernt Jorgensen, Nina Fons Johnsen, Thomas Maribo, Stig Brondum, Gunnar Gislason, Maria Kristiansen
Summary: The study highlights the need for vocational rehabilitation programs to be incorporated into comprehensive cardiac rehabilitation programs in order to identify individuals in need of support and to improve coordination of care across healthcare and social care sectors. This includes involving employers, healthcare professionals, and social workers in personalized return-to-work strategies.
DISABILITY AND REHABILITATION
(2023)
Article
Cardiac & Cardiovascular Systems
Carlo Alberto Barcella, Daniel Molager Christensen, Lars Idorn, Nishan Mudalige, Morten Malmborg, Frederik Folke, Christian Torp-Pedersen, Gunnar Gislason, Mohamad El-Chouli
Summary: This epidemiological study based on a registry found that patients with congenital heart disease (CHD) have a higher risk of out-of-hospital cardiac arrest (OHCA) compared to the general population. However, the 30-day survival rate for OHCA patients with CHD is similar to that of OHCA patients without CHD, and this survival relies on pre-hospital cardiopulmonary resuscitation and defibrillation.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Daniel Molager Christensen, Jarl Emanuel Strange, Mohamad El-Chouli, Alexander Christian Falkentoft, Morten Malmborg, Nina Nouhravesh, Gunnar Gislason, Morten Schou, Christian Torp-Pedersen, Thomas S. G. Sehested
Summary: The study found that noncardiovascular morbidity and mortality increased among MI patients, highlighting the need for further attention to noncardiovascular outcomes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)