Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria

Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site

(2014) Harkewal Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple mechanisms of action of pyridoxine in primary hyperoxaluria type 1

(2013) Sonia Fargue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

4-Hydroxy-2-oxoglutarate aldolase inactivity in primary hyperoxaluria type 3 and glyoxylate reductase inhibition

(2012) Travis J. Riedel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Primary hyperoxalurias: Disorders of glyoxylate detoxification

(2012) Eduardo Salido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hyperoxaluria and systemic oxalosis: an update on current therapy and future directions

(2012) Bodo B Beck et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Primary hyperoxaluria type III—a model for studying perturbations in glyoxylate metabolism

(2012) Ruth Belostotsky et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Expression in Escherichia coli of the catalytic domain of human proline oxidase

(2012) Elena Tallarita et al.   PROTEIN EXPRESSION AND PURIFICATION

Metabolism of [13C5]hydroxyproline in vitro and in vivo: implications for primary hyperoxaluria

(2011) Juquan Jiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Steady-state kinetic mechanism of the proline:ubiquinone oxidoreductase activity of proline utilization A (PutA) from Escherichia coli

(2011) Michael A. Moxley et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Primary Hyperoxaluria Type III Gene HOGA1 (Formerly DHDPSL) as a Possible Risk Factor for Idiopathic Calcium Oxalate Urolithiasis

(2011) C. G. Monico et al.   Clinical Journal of the American Society of Nephrology

Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria

(2011) Travis J. Riedel et al.   PLoS One

Mutations in DHDPSL Are Responsible For Primary Hyperoxaluria Type III

(2010) Ruth Belostotsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Purification and characterization of Put1p from Saccharomyces cerevisiae

(2010) Srimevan Wanduragala et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum

(2010) D. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Conserved Active Site Tyrosine Residue of Proline Dehydrogenase Helps Enforce the Preference for Proline over Hydroxyproline as the Substrate†‡

(2009) Elizabeth L. Ostrander et al.   BIOCHEMISTRY

The primary hyperoxalurias

(2009) Bernd Hoppe et al.   KIDNEY INTERNATIONAL

Increased protein intake on controlled oxalate diets does not increase urinary oxalate excretion

(2009) John Knight et al.   UROLOGICAL RESEARCH

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS