Comparative structural analysis of the caspase family with other clan CD cysteine peptidases

Porphyromonas gingivalisVirulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases

(2013) Iñaki de Diego et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation

(2013) E. Dall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New types of metacaspases in phytoplankton reveal diverse origins of cell death proteases

(2013) C J Choi et al.   Cell Death & Disease

The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays

(2013) Qin Cao et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanism and specificity of the human paracaspase MALT1

(2012) Janna Hachmann et al.   BIOCHEMICAL JOURNAL

Antagonic activities of Trypanosoma cruzi metacaspases affect the balance between cell proliferation, death and differentiation

(2012) M Laverrière et al.   CELL DEATH AND DIFFERENTIATION

Crystal Structure of the Yeast Metacaspase Yca1

(2012) Ada Hang-Heng Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Two-Step Activation Mechanism of MALT1 Paracaspase

(2012) Jens Staal et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Determinants of MALT1 Protease Activity

(2012) Christian Wiesmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Prokaryotic Caspase Homologs: Phylogenetic Patterns and Functional Characteristics Reveal Considerable Diversity

(2012) Johannes Asplund-Samuelsson et al.   PLoS One

Crystal structure of a Trypanosoma brucei metacaspase

(2012) K. McLuskey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leishmania mexicana metacaspase is a negative regulator of amastigote proliferation in mammalian cells

(2012) E Castanys-Muñoz et al.   Cell Death & Disease

Activation of legumain involves proteolytic and conformational events, resulting in a context- and substrate-dependent activity profile

(2011) Elfriede Dall et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Prediction of a caspase-like fold inTannerella forsythiavirulence factor PrtH

(2011) Jimin Pei et al.   CELL CYCLE

Metacaspases

(2011) L Tsiatsiani et al.   CELL DEATH AND DIFFERENTIATION

Calcium-dependent Activation and Autolysis ofArabidopsisMetacaspase 2d

(2011) Naohide Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trypanosoma bruceiMetacaspase 4 Is a Pseudopeptidase and a Virulence Factor

(2011) William R. Proto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins

(2011) Aimee Shen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2011) N. D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Arabidopsis metacaspase 2d is a positive mediator of cell death induced during biotic and abiotic stresses

(2011) Naohide Watanabe et al.   PLANT JOURNAL

Plasmodium falciparum Metacaspase PfMCA-1 Triggers a z-VAD-fmk Inhibitable Protease to Promote Cell Death

(2011) Benoît Meslin et al.   PLoS One

Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region

(2011) J. W. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The JCSG high-throughput structural biology pipeline

(2010) Marc-André Elsliger et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Metacaspases are not caspases – always doubt

(2010) M Enoksson et al.   CELL DEATH AND DIFFERENTIATION

Substrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6

(2010) Sravanti Vaidya et al.   JOURNAL OF MOLECULAR BIOLOGY

Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major

(2010) Habib Zalila et al.   MOLECULAR MICROBIOLOGY

Involvement of the Aspergillus nidulans protein kinase C with farnesol tolerance is related to the unfolded protein response

(2010) Ana Cristina Colabardini et al.   MOLECULAR MICROBIOLOGY

Metacaspase Yca1 is required for clearance of insoluble protein aggregates

(2010) R. E. C. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis Type I Metacaspases Control Cell Death

(2010) N. S. Coll et al.   SCIENCE

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Molecular Mechanism for Autoprocessing of MARTX Toxin ofVibrio choleraeat Multiple Sites

(2009) Katerina Prochazkova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing inClostridium difficileToxin A

(2009) Rory N. Pruitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin

(2009) Aimee Shen et al.   Nature Chemical Biology

Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells

(2008) Guy Klaiman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics

(2008) Robin E. C. Lee et al.   PLoS One

Small Molecule-Induced Allosteric Activation of the Vibrio cholerae RTX Cysteine Protease Domain

(2008) P. J. Lupardus et al.   SCIENCE