期刊
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
卷 1862, 期 3, 页码 319-328出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbagrm.2018.09.008
关键词
-
资金
- Biotechnology and Biological Sciences Research Council (BBSRC), UK [BB/N014839/1, BB/N005430/1]
- White Rose BBSRC doctoral training programme
- BBSRC [BB/N005430/1, BB/N014839/1] Funding Source: UKRI
During synthesis, mRNA undergoes a number of modifications such as capping, splicing and polyadenylation. These processes are coupled with the orderly deposition of the TREX complex on the mRNA and subsequent recruitment of the NXF1-P15 heterodimer which stimulates the nuclear export of mature mRNAs. mRNAs also undergo a number of internal modifications, the most common of which is the N-6-methyladenosine (m(6)A) modification. In this review we discuss the recent evidence of coupling between the m(6)A modification, RNA processing and export.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据