Beneficial effects of spermidine on cardiovascular health and longevity suggest a cell type-specific import of polyamines by cardiomyocytes

Higher spermidine intake is linked to lower mortality: a prospective population-based study

(2018) Stefan Kiechl et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Common traffic routes for imported spermine and endosomal glypican-1-derived heparan sulfate in fibroblasts

(2018) Fang Cheng et al.   EXPERIMENTAL CELL RESEARCH

ATP Release Channels

(2018) Akiyuki Taruno   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Difluoromethylornithine Combined with a Polyamine Transport Inhibitor Is Effective against Gemcitabine Resistant Pancreatic Cancer

(2018) Sarah B. Gitto et al.   MOLECULAR PHARMACEUTICS

Spermidine in health and disease

(2018) Frank Madeo et al.   SCIENCE

Targeting polyamine metabolism for cancer therapy and prevention

(2016) T. R. Murray-Stewart et al.   BIOCHEMICAL JOURNAL

Functions of Polyamines in Mammals

(2016) Anthony E. Pegg   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardioprotection and lifespan extension by the natural polyamine spermidine

(2016) Tobias Eisenberg et al.   NATURE MEDICINE

Inhibition of Polyamine Uptake Potentiates the Anti-Proliferative Effect of Polyamine Synthesis Inhibition and Preserves the Contractile Phenotype of Vascular Smooth Muscle Cells

(2015) Mario Grossi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Arginase: an old enzyme with new tricks

(2015) Ruth B. Caldwell et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Vascular smooth muscle cell proliferation depends on caveolin-1-regulated polyamine uptake

(2014) Mario Grossi et al.   BIOSCIENCE REPORTS

Polyamine Transport Inhibitors: Design, Synthesis, and Combination Therapies with Difluoromethylornithine

(2014) Aaron Muth et al.   JOURNAL OF MEDICINAL CHEMISTRY

Polyamines and membrane transporters

(2013) Ahmed A. Abdulhussein et al.   AMINO ACIDS

Recent advances in the molecular biology of metazoan polyamine transport

(2011) R. Poulin et al.   AMINO ACIDS

Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract

(2010) Takeshi Uemura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Human Carnitine Transporter SLC22A16 Mediates High Affinity Uptake of the Anticancer Polyamine Analogue Bleomycin-A5

(2009) Mustapha Aouida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular characterization of a human cation-Cl−cotransporter (SLC12A8A, CCC9A) that promotes polyamine and amino acid transport

(2009) Nikolas D. Daigle et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Modulation of Caveolin-1 Expression Can Affect Signalling through the Phosphatidylinositol 3-Kinase/Akt Pathway and Cellular Proliferation in Response to Insulin-Like Growth Factor I

(2008) Laura C. Matthews et al.   ENDOCRINOLOGY

ActivatedK-RAS increases polyamine uptake in human colon cancer cells through modulation of caveolar endocytosis

(2008) Upal K. Basu Roy et al.   MOLECULAR CARCINOGENESIS