标题
LRRK2 and Rab GTPases
作者
关键词
-
出版物
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 46, Issue 6, Pages 1707-1712
出版商
Portland Press Ltd.
发表日期
2018-11-23
DOI
10.1042/bst20180470
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Parkinson's disease-associated mutant LRRK2 phosphorylates Rab7L1 and modifies trans-Golgi morphology
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- Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
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- Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration
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- LRRK2 kinase in Parkinson's disease
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- LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis
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- A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
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- LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network
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- Rab GTPases: master regulators that establish the secretory and endocytic pathways
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- Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis
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- Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
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- LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts
- (2016) Tomoki Kuwahara et al. Scientific Reports
- The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis
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- TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells
- (2014) Luciana I. Gallo et al. MOLECULAR BIOLOGY OF THE CELL
- A Role of Rab29 in the Integrity of the Trans-Golgi Network and Retrograde Trafficking of Mannose-6-Phosphate Receptor
- (2014) Shicong Wang et al. PLoS One
- Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
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- Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB
- (2013) Zhong Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk
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- GTPase Networks in Membrane Traffic
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- Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella
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