Article
Oncology
Huixin Zhang, Muoyan Xu, Jiashen Shao, Huifang Kong, Xudong Gao, Wei Zhang, Xiujuan Chang, Bin Yang, Yan Chen, Zheng Dong, Jiagan Huang, Zhen Zeng, Yongping Yang
Summary: The aim of this study was to assess whether elderly patients with small HCC could benefit from cryoablation. The study found significant differences in overall survival and tumor progression between younger and elderly patients, but no significant difference in progression-free survival. Chronic liver disease, albumin, and bilirubin levels were associated with the prognosis of small HCCs.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hang Zheng, Kaiwen Liu, Yao Yang, Bo Liu, Xinya Zhao, Yong Chen, Yuemin Feng, Min Meng, Xu Tan, Qiang Zhu
Summary: Compared to RFA, MWA showed better tumor control for subcapsular HCC within the Milan criteria. There was no difference in the incidence of major complications between the two groups.
EUROPEAN RADIOLOGY
(2022)
Article
Surgery
Rosalinda Filippo, Maria Conticchio, Francesca Ratti, Riccardo Inchingolo, Maximiliano Gelli, Ferdinando Massimiliano Anelli, Alexis Laurent, Giulio Cesare Vitali, Paolo Magistri, Giacomo Assirati, Emanuele Felli, Taiga Wakabayashi, Patrick Pessaux, Tullio Piardi, Fabrizio Di Benedetto, Nicola de'Angelis, Delgado Francisco Javier Briceno, Antonio Gaetano Rampoldi, Rene Adam, Daniel Cherqui, Luca Aldrighetti, Riccardo Memeo
Summary: This study compared the outcomes of liver resection (LR) and radiofrequency ablation (RFA) in octogenarian patients with hepatocellular carcinoma (HCC). The results showed that LR had a higher rate of complications, longer operative time, and hospital stays, but had better long-term outcomes in terms of survival rate.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chao An, Wang-Zhong Li, Zhi-Mei Huang, Xiao-Ling Yu, Yu-Zhi Han, Fang-Yi Liu, Song-Song Wu, Jie Yu, Ping Liang, Jinhua Huang
Summary: In patients with small single perivascular hepatocellular carcinoma, microwave ablation exhibited better tumor control than radiofrequency ablation, with a significantly higher local tumor progression rate observed in the radiofrequency ablation group. Additionally, there was a significant interaction effect of ablation modality and type of peritumoral vessel on local tumor progression, with differences observed in periportal HCC but not perivenous HCC.
EUROPEAN RADIOLOGY
(2021)
Article
Oncology
Hidekatsu Kuroda, Tomoaki Nagasawa, Yudai Fujiwara, Hiroki Sato, Tamami Abe, Yohei Kooka, Kei Endo, Takayoshi Oikawa, Kei Sawara, Yasuhiro Takikawa
Summary: Microwave ablation using Thermosphere(TM) technology showed similar overall survival and recurrence-free survival outcomes compared to radiofrequency ablation for hepatocellular carcinoma. Despite no significant differences in survival outcomes between the two methods, microwave ablation required fewer insertions, making it a recommended treatment option for tumors larger than 2 cm.
Article
Surgery
Hong Jae Jeon, Hyuk Soo Eun, In Sun Kwon, Byung Seok Lee, Eaum Seok Lee, Woo Sun Rou, Jae Kyu Sung, Hee Seok Moon, Sun Hyung Kang, Hyun Seok Lee, Seok-Hwan Kim, Kwangsik Chun, Seok Hyun Kim
Summary: This study compared the therapeutic outcomes of laparoscopic radiofrequency ablation (LRFA) and percutaneous radiofrequency ablation (PRFA) in patients with hepatocellular carcinoma (HCC). The results revealed that LRFA was associated with longer recurrence-free survival and favorable overall survival compared to PRFA. Therefore, LRFA should be considered as the primary therapy for eligible HCC patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Oncology
Takuya Wada, Katsutoshi Sugimoto, Kentaro Sakamaki, Hiroshi Takahashi, Tatsuya Kakegawa, Yusuke Tomita, Masakazu Abe, Yu Yoshimasu, Hirohito Takeuchi, Takao Itoi
Summary: This study compared the outcomes of radiofrequency ablation (RFA), microwave ablation (MWA), and irreversible electroporation (IRE) in treating early stage hepatocellular carcinoma (HCC). The results showed that IRE had a significantly lower 2-year local tumor progression (LTP) rate compared to RFA. There were no significant differences in LTP rates between IRE and MWA, and between RFA and MWA. Therefore, IRE may be a better first-line treatment option for small perivascular HCC.
Article
Multidisciplinary Sciences
Xinyuan Zhang, Yujing Xin, Yi Chen, Xiang Zhou
Summary: This meta-analysis evaluates the prognostic role of albumin-to-alkaline phosphatase ratio (AAPR) in hepatocellular carcinoma (HCC) patients. Data from 12 cohorts totaling 2634 patients were analyzed, and the results demonstrate that lower AAPR predicts inferior overall survival and recurrence-free survival rates. Despite some heterogeneity and publication bias, subgroup and sensitivity analyses confirm the association between AAPR and survival outcomes. These findings suggest that AAPR holds promise as a prognostic indicator for HCC.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas Le Corroller, Thomas Vives, Jean-Camille Mattei, Vanessa Pauly, Daphne Guenoun, Alexandre Rochwerger, Pierre Champsaur
Summary: This study retrospectively analyzed 50 patients who underwent CT-guided cryoablation for osteoid osteoma treatment, showing that this approach was safe, effective, and durable, with a high clinical success rate of 96%. The majority of patients could undergo the treatment without general anesthesia, and the pain relief was significant both in the short and long term follow-up.
Article
Oncology
Alessandro Cucchetti, Omar Elshaarawy, Guohong Han, Charing C. N. Chong, Carla Serra, Joanne Marie O'Rourke, Richard Crew, Cristina Felicani, Giorgio Ercolani, Tahir Shah, Arndt Vogel, Paul B. S. Lai, Philip J. Johnson
Summary: This study developed a statistical model to predict cure after ablation and compared the curative potential of different therapies. The cure fraction for HCC treated with ablation was found to be around 20% to 30%, similar to resection but inferior to transplantation.
BRITISH JOURNAL OF CANCER
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Elena Serrano, Federico Zarco, Anne E. Gill, C. Matthew Hawkins, Napoleon Macias, Emilio J. Inarejos Clemente, Ferran Torner, Ignasi Barber, Daniel Corominas, Enrique Ladera Gonzalez, Antonio Lopez-Rueda, Fernando M. Gomez
Summary: Percutaneous cryoablation is potentially safe and effective for treating chondroblastoma and osteoblastoma in children and adolescents, with technical and clinical success achieved in all patients, and no evidence of recurrence on imaging follow-up for at least 6 months.
INSIGHTS INTO IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mansur A. Ghani, Amandip Bangar, Yunpeng Yang, Eunkyeong Jung, Consuelo Sauceda, Tyler Mandt, Sourabh Shukla, Nicholas J. G. Webster, Nicole F. Steinmetz, Isabel G. Newton
Summary: The study aimed to test the effectiveness of cryoablation combined with intratumoral immunomodulating nanoparticles (CPMV) in inducing systemic antitumoral immunity in a murine model of hepatocellular carcinoma (HCC). The results showed that cryoablation combined with intratumoral CPMV was the most effective treatment for the treated tumors and also slowed the growth of untreated tumors.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Robert Peter Reimer, Nils Grosse Hokamp, Julius Niehoff, David Zopfs, Simon Lennartz, Mariam Heidar, Roger Wahba, Dirk Stippel, David Maintz, Daniel Pinto dos Santos, Christian Wybranski
Summary: The study shows that low-keV virtual monoenergetic images and iodine maps derived from SDCT provide superior early assessment of technique efficacy in HCC patients who underwent MWA compared to conventional images.
Article
Oncology
Hui-Zhou Li, Jie Tan, Tian Tang, Tian-Zhi An, Jun-Xiang Li, Yu-Dong Xiao
Summary: This study compared the treatment efficacy and down-staging rate of combined TACE-MWA and TACE alone in patients with unresectable HCC beyond the Milan criteria. The results indicate that TACE-MWA offers better overall survival and progression-free survival compared to TACE alone, as well as a higher downstaging rate, potentially increasing the chance of liver transplantation.
JOURNAL OF HEPATOCELLULAR CARCINOMA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seong Eun Ko, Min Woo Lee, Soohyun Ahn, Hyunchul Rhim, Tae Wook Kang, Kyoung Doo Song, Jong Man Kim, Gyu-Seong Choi, Dong Ik Cha, Ji Hye Min, Dong Hyun Sinn, Moon Seok Choi, Hyo Keun Lim
Summary: This study compared the therapeutic outcomes of laparoscopic hepatic resection (LHR) and laparoscopic radiofrequency ablation (LRFA) for single subcapsular hepatocellular carcinoma (HCC) measuring 1-3 cm. The results showed no significant difference in therapeutic outcomes between the two methods.
KOREAN JOURNAL OF RADIOLOGY
(2022)
