Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults

Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults

(2018) Ameya S Kulkarni et al.   AGING CELL

Postmeal exercise blunts postprandial glucose excursions in people on metformin monotherapy

(2017) Melissa L. Erickson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal muscle mitochondrial protein synthesis and respiration in response to the energetic stress of an ultra-endurance race

(2017) Adam R. Konopka et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race

(2017) Benjamin Miller et al.   PLoS One

Metformin as a Tool to Target Aging

(2016) Nir Barzilai et al.   Cell Metabolism

Glucose Levels and Risk of Frailty

(2016) Oleg Zaslavsky et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes

(2016) Adam R. Konopka et al.   Cell Reports

Defects in Mitochondrial Efficiency and H2O2Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training

(2015) Adam R. Konopka et al.   DIABETES

Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls

(2014) C. A. Bannister et al.   DIABETES OBESITY & METABOLISM

Commonly used diabetes and cardiovascular medications and cancer recurrence and cancer-specific mortality: a review of the literature

(2014) Jennifer W Wu et al.   Expert Opinion On Drug Safety

Type 2 Diabetes and Antidiabetic Medications in Relation to Dementia Diagnosis

(2014) Chin Cheng et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

(2014) Anila K. Madiraju et al.   NATURE

Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner

(2014) Bart Wessels et al.   PLoS One

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

(2014) William W Wheaton et al.   eLife

Does metformin modify the effect on glycaemic control of aerobic exercise, resistance exercise or both?

(2013) Normand G. Boulé et al.   DIABETOLOGIA

Glucose Levels and Risk of Dementia

(2013) Paul K. Crane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ambulant 24-h glucose rhythms mark calendar and biological age in apparently healthy individuals

(2012) Carolien A. Wijsman et al.   AGING CELL

Telomere Length and Long-Term Endurance Exercise: Does Exercise Training Affect Biological Age? A Pilot Study

(2012) Ida Beate Ø. Østhus et al.   PLoS One

A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

(2011) Benjamin F. Miller et al.   AGING CELL

Independent and Combined Effects of Exercise Training and Metformin on Insulin Sensitivity in Individuals With Prediabetes

(2011) S. K. Malin et al.   DIABETES CARE

Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation

(2011) Matthew M. Robinson et al.   FASEB JOURNAL

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals

(2010) Carrie G. Sharoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats

(2010) Daniel A. Kane et al.   FREE RADICAL BIOLOGY AND MEDICINE

Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity

(2010) Thomas J. LaRocca et al.   MECHANISMS OF AGEING AND DEVELOPMENT

AMPK and the biochemistry of exercise: implications for human health and disease

(2009) Erik A. Richter et al.   BIOCHEMICAL JOURNAL

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Telomere length measurement by a novel monochrome multiplex quantitative PCR method

(2009) R. M. Cawthon   NUCLEIC ACIDS RESEARCH

Impact of metformin on peak aerobic capacity

(2008) Barry Braun et al.   Applied Physiology Nutrition and Metabolism