Ultralong Circulating Lollipop-Like Nanoparticles Assembled with Gossypol, Doxorubicin, and Polydopamine via π-π Stacking for Synergistic Tumor Therapy

Meet Our Editorial Board Member

(2018) Werner Sieghart   CURRENT MEDICINAL CHEMISTRY

Pharmacokinetics, biodistribution, and bioavailability of gossypol-loaded Pluronic ® F127 nanoparticles

(2018) Ying Wang et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Recent advances in gossypol derivatives and analogs: a chemistry and biology view

(2017) Yuzhi Lu et al.   Future Medicinal Chemistry

Chemotherapeutic drug-photothermal agent co-self-assembling nanoparticles for near-infrared fluorescence and photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy

(2017) Yang Li et al.   JOURNAL OF CONTROLLED RELEASE

Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations

(2017) Hangxiang Wang et al.   Theranostics

Carrier-Free, Chemophotodynamic Dual Nanodrugs via Self-Assembly for Synergistic Antitumor Therapy

(2016) Ruiyun Zhang et al.   ACS Applied Materials & Interfaces

Codelivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multidrug Resistance and Tumor Metastasis

(2016) Xiao Wei et al.   ADVANCED FUNCTIONAL MATERIALS

Long Circulation Red-Blood-Cell-Mimetic Nanoparticles with Peptide-Enhanced Tumor Penetration for Simultaneously Inhibiting Growth and Lung Metastasis of Breast Cancer

(2016) Jinghan Su et al.   ADVANCED FUNCTIONAL MATERIALS

Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation

(2016) Xinyu Wang et al.   BIOMATERIALS

Injectable (−)-gossypol-loaded Pluronic P85 micelles for cancer chemoradiotherapy

(2016) Keishiro Tomoda et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: A robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy

(2016) Yan Zou et al.   JOURNAL OF CONTROLLED RELEASE

Long circulating reduced graphene oxide–iron oxide nanoparticles for efficient tumor targeting and multimodality imaging

(2016) Cheng Xu et al.   Nanoscale

Nanodrug Formed by Coassembly of Dual Anticancer Drugs to Inhibit Cancer Cell Drug Resistance

(2015) Yuanyuan Zhao et al.   ACS Applied Materials & Interfaces

Development of a Graphene Oxide Nanocarrier for Dual-Drug Chemo-phototherapy to Overcome Drug Resistance in Cancer

(2015) Tuan Hiep Tran et al.   ACS Applied Materials & Interfaces

Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles

(2015) Yang Shi et al.   ACS Nano

Mulberry-like dual-drug complicated nanocarriers assembled with apogossypolone amphiphilic starch micelles and doxorubicin hyaluronic acid nanoparticles for tumor combination and targeted therapy

(2015) Ke Li et al.   BIOMATERIALS

Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy

(2015) Peng Zhang et al.   BIOMATERIALS

Stealth CD44-targeted hyaluronic acid supramolecular nanoassemblies for doxorubicin delivery: Probing the effect of uncovalent pegylation degree on cellular uptake and blood long circulation

(2015) Xiaopeng Han et al.   JOURNAL OF CONTROLLED RELEASE

Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency

(2015) Kaimin Cai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Smart doxorubicin nanoparticles with high drug payload for enhanced chemotherapy against drug resistance and cancer diagnosis

(2015) Caitong Yu et al.   Nanoscale

Self-carried curcumin nanoparticles for in vitro and in vivo cancer therapy with real-time monitoring of drug release

(2015) Jinfeng Zhang et al.   Nanoscale

Investigating the Impact of Nanoparticle Size on Active and Passive Tumor Targeting Efficiency

(2014) Edward A. Sykes et al.   ACS Nano

Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers

(2014) Joonyoung Park et al.   ACS Nano

Long Circulating Self-Assembled Nanoparticles from Cholesterol-Containing Brush-Like Block Copolymers for Improved Drug Delivery to Tumors

(2014) Thanh-Huyen Tran et al.   BIOMACROMOLECULES

Co-delivery of doxorubicin and paclitaxel by PEG-polypeptide nanovehicle for the treatment of non-small cell lung cancer

(2014) Shixian Lv et al.   BIOMATERIALS

Polyglutamic acid–PEG nanocapsules as long circulating carriers for the delivery of docetaxel

(2014) Giovanna Lollo et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Combination of Small Molecule Prodrug and Nanodrug Delivery: Amphiphilic Drug–Drug Conjugate for Cancer Therapy

(2014) Ping Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

(2014) Vladimir P. Torchilin   NATURE REVIEWS DRUG DISCOVERY

A unique squalenoylated and nonpegylated doxorubicin nanomedicine with systemic long-circulating properties and anticancer activity

(2014) A. Maksimenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mussel-Inspired Polydopamine: A Biocompatible and Ultrastable Coating for Nanoparticles in Vivo

(2013) Xiangsheng Liu et al.   ACS Nano

Π–Π Stacking Increases the Stability and Loading Capacity of Thermosensitive Polymeric Micelles for Chemotherapeutic Drugs

(2013) Yang Shi et al.   BIOMACROMOLECULES

Carrier-free functionalized multidrug nanorods for synergistic cancer therapy

(2013) Mengjiao Zhou et al.   BIOMATERIALS

Novel Nanoparticles Generated by Polymeric Amphiphiles with π–π Conjugated Small Molecules for Anti-Tumor Drug Delivery

(2013) Xin Deng et al.   Journal of Biomedical Nanotechnology

Carrier-free, functionalized drug nanoparticles for targeted drug delivery

(2012) Wei Li et al.   CHEMICAL COMMUNICATIONS

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

pH-Controlled Delivery of Doxorubicin to Cancer Cells, Based on Small Mesoporous Carbon Nanospheres

(2012) Jie Zhu et al.   Small

Nanomedicine for targeted cancer therapy: Towards the overcoming of drug resistance

(2011) Alina Shapira et al.   DRUG RESISTANCE UPDATES

First-In-Man Study of CPX-351: A Liposomal Carrier Containing Cytarabine and Daunorubicin in a Fixed 5:1 Molar Ratio for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia

(2011) Eric J. Feldman et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects

(2010) Hiroshi Maeda   BIOCONJUGATE CHEMISTRY

Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects

(2010) Jin-Wook Yoo et al.   CURRENT PHARMACEUTICAL DESIGN

An improved ultrasound-assisted extraction process of gossypol acetic acid from cottonseed soapstock

(2009) Guangfeng Jia et al.   AICHE JOURNAL

Do Special Noncovalent π–π Stacking Interactions Really Exist?

(2008) Stefan Grimme   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Pulse gradient, large-volume injection, high-throughput ultra-performance liquid chromatographic/tandem mass spectrometry bioanalysis for measurement of plasma amrubicin and its metabolite amrubicinol

(2008) Yingfei Li et al.   JOURNAL OF CHROMATOGRAPHY A

High-Efficiency Loading and Controlled Release of Doxorubicin Hydrochloride on Graphene Oxide

(2008) Xiaoying Yang et al.   Journal of Physical Chemistry C