Article
Multidisciplinary Sciences
Jonas B. Fischer, Lisa Kobayashi Frisk, Felix Scholkmann, Raquel Delgado-Mederos, Mercedes Mayos, Turgut Durduran
Summary: The study found that wearing masks can lead to small but significant changes in cerebral hemodynamics, comparable to those seen during daily life activities. This research provides a basis for larger studies on the effects of mask wearing in different populations and situations.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Nutrition & Dietetics
Matjaz Macuh, Nenad Kojic, Bojan Knap
Summary: This study aimed to evaluate the effects of nitrate supplements based on habitual dietary nitrate intake in highly trained football players. The results showed that nitrate supplementation had a significant positive effect on performance if baseline dietary nitrate intake was below 300 mg. However, no clear conclusions could be drawn for higher baseline dietary nitrate intake due to the small sample size. The participants' daily nitrate intake was measured at 165 mg, with the majority coming from nitrate-rich vegetables.
Article
Biochemical Research Methods
Weikang Sun, Bingdong Cai, Jie Rao, Feifan Zhou
Summary: Photoacoustic imaging was used to investigate the effects of alcohol on cerebrovascular changes in mice. It was found that low doses of alcohol increased blood volume and neuronal activation, while high doses of alcohol decreased blood volume and had progressive effects on the immune microenvironment, cerebrovascular structure, and addictive behavior.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Environmental Sciences
Chunmeng Li, Haichao Wang, Xiaorui Chen, Tianyu Zhai, Xuefei Ma, Xinping Yang, Shiyi Chen, Xin Li, Limin Zeng, Keding Lu
Summary: In this study, the measurements of two types of organic nitrates (ONs), peroxy nitrates (PNs) and alkyl nitrates (ANs), in Chengdu, China, during summer 2019, were reported. The average concentrations of PNs and ANs were found to be in the middle and upper end of the reported levels in China. The study showed higher concentrations of PNs and ANs during photochemical pollution period. The box model simulation was able to reproduce PNs during the pollution episodes, but showed overestimation in other periods.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Endocrinology & Metabolism
Hanne Stotesbury, Patrick W. Hales, Melanie Koelbel, Anna M. Hood, Jamie M. Kawadler, Dawn E. Saunders, Sati Sahota, David C. Rees, Olu Wilkey, Mark Layton, Maria Pelidis, Baba P. D. Inusa, Jo Howard, Subarna Chakravorty, Chris A. Clark, Fenella J. Kirkham
Summary: Using arterial spin labelling (ASL), this study quantified high venous signal in patients with sickle cell anemia (SCA) and explored its associations with arterial oxygen content, disease-modifying treatments, cerebral infarction, and cognitive performance. The findings suggest the usefulness of multiTI ASL in objectively quantifying and identifying markers of regional hemodynamic stress in patients with SCA.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Article
Physiology
Lianne J. Trigiani, Clotilde Lecrux, Jessika Royea, Julie L. Lavoie, Frederic Lesage, Louise Pilote, Edith Hamel
Summary: This study investigated the potential impact of preeclampsia on cognitive deficits in mothers and offspring using a transgenic mouse model, revealing higher cerebral blood flow responses and hemodynamic alterations in the pups of R(+)A(+) mice compared to control pups.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Tanja Knopp, Tabea Bieler, Rebecca Jung, Julia Ringen, Michael Molitor, Annika Jurda, Thomas Muenzel, Ari Waisman, Philip Wenzel, Susanne Helena Karbach, Johannes Wild
Summary: Different dietary protein levels had minimal impact on the development and severity of IMQ-induced psoriasis, but aggravated the systemic pro-inflammatory phenotype. High protein diet slightly aggravated skin inflammation, while both high and low protein diets increased circulating neutrophils and reactive oxygen species after IMQ-treatment.
Article
Biochemistry & Molecular Biology
Forough Jahandideh, Sareh Panahi, Ronan M. N. Noble, Ferrante S. Gragasin, Rachel G. Khadaroo, Kimberly F. Macala, Stephane L. Bourque
Summary: Sepsis is associated with circulatory dysfunction and organ injury, and the loss of vasoregulatory mechanisms contributes to decreased organ perfusion. This study investigated the development of vascular dysfunction as sepsis progressed to septic shock and found that the mesenteric vasculature exhibited dysregulation before the renal and carotid arteries.
Article
Endocrinology & Metabolism
Evelien S. Hoogeveen, Nadine Pelzer, Eidrees Ghariq, Matthias J. P. van Osch, Albert Dahan, Gisela M. Terwindt, Mark C. Kruit
Summary: The impaired cerebrovascular reactivity in RVCL-S patients, especially those aged 40 years or older, could be an important factor in the pathophysiology of the disease. Early reduction in gray matter CVR may be associated with white matter lesion volume in RVCL-S patients.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2021)
Article
Dentistry, Oral Surgery & Medicine
Maria Vazquez-Reza, Iria Lopez-Dequidt, Alberto Ouro, Ramon Iglesias-Rey, Francisco Campos, Juan Blanco, Manuel Rodriguez-Yanez, Jose Castillo, Tomas Sobrino, Yago Leira
Summary: This study found an association between periodontitis and subclinical intracranial atherosclerosis as well as carotid atherosclerosis in elderly subjects with hypertension. Additionally, periodontitis was associated with other markers of atherosclerosis in different vascular territories.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Peripheral Vascular Disease
Thomas Willmott, Laura Ormesher, Andrew J. Mcbain, Gavin J. Humphreys, Jenny E. Myers, Gurdeep Singh, Jon O. Lundberg, Eddie Weitzberg, Carina Nihlen, Elizabeth C. Cottrell
Summary: This study aimed to investigate the role of oral microbiota profiles and oral nitrate-reducing capacity in explaining individual differences in blood pressure (BP) lowering following dietary nitrate supplementation. The results showed that women with hypertension had lower salivary nitrite concentrations and reduced abundance of nitrate-reducing bacteria compared to normotensive women. Oral nitrate reductase (NaR) activity did not differ significantly between pregnant and nonpregnant women, but it tended to be lower in hypertensive women. Oral NaR activity was associated with both baseline diastolic BP and changes in diastolic BP after acute nitrate intake.
Article
Medicine, General & Internal
Mario Podrug, Pjero Koren, Edita Drazic Maras, Josip Podrug, Viktor Culic, Maria Perissiou, Rosa Maria Bruno, Ivana Mudnic, Mladen Boban, Ana Jeroncic
Summary: COVID-19-associated vascular disease complications are primarily related to endothelial dysfunction, and the long-term effects on vascular structure and function remain unexplored. A study on patients diagnosed with mild COVID-19 found that arterial stiffness and hemodynamic parameters showed changes post-infection. The results suggest that mild COVID-19 can lead to clinically significant progression of vascular impairment within 2-3 months, and some of these changes may be triggered by an autoimmune response to COVID-19.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Clinical Neurology
Mark B. Vestergaard, Jette L. Frederiksen, Henrik B. W. Larsson, Stig P. Cramer
Summary: Inflammatory processes in the central nervous system could potentially impair cerebrovascular function in multiple sclerosis patients. However, studies on cerebrovascular reactivity and neurovascular coupling in MS patients have produced diverse results, indicating the need for further research to understand the discrepancies.
FRONTIERS IN NEUROLOGY
(2022)
Article
Agronomy
Paraskevas Parlakidis, George Adamidis, Christos Alexoudis, Paschalina Pythoglou, Sotirios Papadopoulos, Zisis Vryzas
Summary: This study assessed the effectiveness of the adjuvant Dash (R) HC EC against garlic rust as well as the degradation and translocation of two fungicides, boscalid and pyraclostrobin, in plant tissues. It also validated an analytical method for determining the presence of these fungicides in garlic and garlic bulbs. Results showed that the adjuvant improved the efficacy and retention of the fungicides on garlic plants. Boscalid exhibited higher translocation from garlic leaves to garlic bulbs compared to pyraclostrobin. Based on a dietary risk assessment, the use of the adjuvant with boscalid and pyraclostrobin is considered safe 14 days after application.
Article
Computer Science, Interdisciplinary Applications
Jian Xie, Zaiheng Cheng, Lihua Gu, Bokai Wu, Gaojia Zhang, Wenshin Shiu, Rongliang Chen, Zan Wang, Chang Liu, Jie Tu, Xiaochuan Cai, Jia Liu, Zhijun Zhang
Summary: The study utilized a computational fluid dynamics (CFD) approach to detect cerebral hemodynamics, revealing that SVaD patients had reduced outlets, CAV, and tCBF index, along with an increased tCVR index compared to CNCs. Fewer outlets and more WMH were identified as risk factors for SVaD, partially mediated by the tCBF index.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
