Article
Environmental Sciences
Daniel M. Lins, Rosana M. Rocha
Summary: This study investigated the distribution of eight invasive species in Santa Catarina, Brazil, the main mussel production area in the country. The results showed that these species were present in all sites, but their distribution was spatially restricted for both adult and recruit individuals. Propagule pressure was found to be the main driver of distribution for three species, while port distance only explained the distribution of one species.
MARINE POLLUTION BULLETIN
(2022)
Article
Environmental Sciences
Lorenzo Vilizzi, Jeffrey E. Hill, Marina Piria, Gordon H. Copp
Summary: Electronic decision-support tools are increasingly used worldwide to identify and manage potentially invasive species. This study reviews the analytical approaches used in weed risk assessment and provides a protocol for species screening and categorization.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Immunology
Chengbo Long, Feilong Wu, Qiumin Lu, Bing Xie, Chuanbin Shen, Jiayao Li, Yanling Deng, Ping Liang, Yongzhi Yu, Ren Lai
Summary: A new strategy has been developed for rapid and efficient clinical diagnosis of snakebite, which is crucial for successful treatment. By using multi-omics approaches to choose candidate antigens and preparing a double-antibody sandwich ELISA kit, high accuracy and feasibility in identifying snake venoms have been demonstrated.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Natali J. Delorme, Leonie Venter, Anne Rolton, Jessica A. Ericson
Summary: Marine organisms, such as the green-lipped mussel, exhibit biochemical, molecular, and physiological changes when exposed to different levels of heat stress. Analysis of various parameters, including hemocyte concentration, viability, reactive oxygen species production, total antioxidant capacity, and metabolic responses, revealed significant alterations in response to heat shock, with energy metabolism pathways being the most affected.
JOURNAL OF SHELLFISH RESEARCH
(2021)
Article
Infectious Diseases
Yaling Zhao, Ye Zhao, Yu Sun, Lihua Fan, Duoquan Wang, Heng Wang, Xiaodong Sun, Zhi Zheng
Summary: This study developed a sensitive and high-throughput approach for large-scale infectious disease screening. With the multi-section cooperative capture but separate amplification strategy, the method accurately identified the genus and species of Plasmodium without RNA extraction, making it a valuable tool for malaria elimination.
INFECTIOUS DISEASES OF POVERTY
(2022)
Article
Chemistry, Physical
Yijiu Ren, Zhou Zhang, Yunlang She, Yayi He, Dongdong Li, Yixiang Shi, Chuan He, Yang Yang, Wei Zhang, Chang Chen
Summary: Low-dose computed tomography screening and ultrasensitive methods for detecting cell-free DNA (cfDNA) 5-hydroxymethylcytosine (5hmC) in plasma have shown promising results in improving the diagnostic accuracy of early-stage non-small-cell lung cancer (NSCLC) detection. A diagnostic model based on genome-wide 5hmC profiling in cfDNA samples has been developed, which outperforms serum biomarkers and can accurately detect lung cancer and high-risk pulmonary nodules.
Article
Oncology
Meytal Dror Levinsky, Baruch Brenner, Michal Yalon, Zohar Levi, Zvi Livneh, Zoya Cohen, Tamar Paz-Elizur, Rachel Grossman, Zvi Ram, Ilan Volovitz
Summary: Personalized vaccines for cancer immunotherapy can be evaluated by quantifying changes in antigen-specific T cell frequency or activity using ELISpot and FCM. However, background IFN gamma secretion can interfere with the accuracy of these methods. To overcome this, we developed an FCM panel including early activation markers to enable highly sensitive monitoring of low-frequency T cell responses to tumor-associated antigens.
Article
Plant Sciences
Monika Kaluzna, Andjelka Prokic, Aleksa Obradovic, William A. Weldon, Virginia O. Stockwell, Joel F. Pothier
Summary: In this study, a comparative genomics approach was used to identify unique sequences in the publicly available genomes of Xanthomonas arboricola pv. corylina (Xac). Based on these unique sequences, new molecular diagnostic tools were designed for the rapid and accurate detection and identification of Xac.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemical Research Methods
Seungjin Lee, Deahan Nam, Jung Soo Park, Seokjoon Kim, Eun Sung Lee, Byung Seok Cha, Ki Soo Park
Summary: A new highly efficient DNA reporter has been discovered, significantly improving the trans-cleavage activity of Cas proteins and enhancing detection speed and sensitivity.
Article
Environmental Sciences
In-Soo Kim, Hae-Kyung Park, Yong-Jin Kim
Summary: In this study, PCR primers were developed to selectively identify five invasive cyanobacterial genera, providing an important supplement to the current microscopy-based monitoring. The performance of the primers was verified in field samples, demonstrating their effectiveness in identifying the target genera.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Chemistry, Analytical
Shijie Chen, Qiukai Tang, Yanbo Zeng, Yiwen Yang, Tianyi Zhu, Hailong Wang, Longhua Guo, Lei Li, Zhaosheng Qian
Summary: A novel fluorescence aptasensor based on PCN-223 was developed for sensitive detection of prostate-specific antigen (PSA). The aptasensor achieved fluorescence quenching through the interaction between TAMRA-labeled PSA aptamer and PCN-223. The aptasensor showed a good linear relationship between delta F value and PSA concentration, with a detection limit of 0.05 ng mL(-1). PCN-223 exhibited higher quenching efficiency compared to other metal-organic frameworks (MOFs) as quenchers.
Article
Rheumatology
Candace H. Feldman, Cameron Speyer, Rachel Ashby, Bonnie L. Bermas, Shamik Bhattacharyya, Eliza Chakravarty, Brendan Everett, Elizabeth Ferucci, Aimee O. Hersh, Francisco M. Marty, Joseph F. Merola, Rosalind Ramsey-Goldman, Brad H. Rovin, Mary Beth Son, Laura Tarter, Sushrut Waikar, Jinoos Yazdany, Joel S. Weissman, Karen H. Costenbader
Summary: The study aimed to define a set of SLE-specific adverse outcomes that could be prevented with timely, effective ambulatory care. Through a modified Delphi process, 25 SLE-specific conditions were identified as potentially preventable and important on a population level, falling into categories of vaccine-preventable illnesses, medication-related complications, reproductive health-related complications, and SLE-related complications.
ARTHRITIS CARE & RESEARCH
(2021)
Article
Plant Sciences
Yukimi Y. Taniguchi, Udo Gowik, Yuto Kinoshita, Risa Kishizaki, Naoaki Ono, Akiho Yokota, Peter Westhoff, Yuri N. Munekage
Summary: C-4 plants are believed to have evolved from C-3 plants through various intermediate stages, involving changes in gene expression and cell-specific control. Research results indicate that during the establishment of C-4 photosynthesis, gene expression increases gradually and cell-specific control strengthens.
Article
Oncology
Saba Bashir, Haq Nawaz, Muhammad Irfan Majeed, Mashkoor Mohsin, Sabahat Abdullah, Saqib Ali, Nosheen Rashid, Muhammad Kashif, Fatima Batool, Muhammad Abubakar, Shamsheer Ahmad, Aliza Abdulraheem
Summary: The study successfully differentiated carbapenem resistant and susceptible E. coli strains using SERS technique and multivariate data analysis tools, demonstrating the potential application of SERS in strain identification and differentiation.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Chemistry, Analytical
Chen Wang, Huijuan Zeng, Luning Zhang, Yiyun Shen, Bingjie Zou, Shaohua Wang, Qinxin Song, Guohua Zhou
Summary: Acquired ESR1 mutation is a key mechanism of resistance to endocrine therapies in breast cancers. A new strategy using base-specific invasive reaction assisted qPCR for measuring ESR1 mutations in cfDNA showed high specificity and sensitivity, with successful validation in endocrine therapy-resistant breast cancers.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
