Article
Medicine, General & Internal
Ann-Marie Rosland, John D. Piette, Ranak Trivedi, Aaron Lee, Shelley Stoll, Ada O. Youk, D. Scott Obrosky, Denise Deverts, Eve A. Kerr, Michele Heisler
Summary: The CO-IMPACT intervention was found to improve patient activation and self-efficacy, but did not significantly impact physiological outcomes compared to standard care, according to a randomized clinical trial. More intensive coaching of supporters or targeting patients with less support and fewer resources may be necessary for greater impact.
Editorial Material
Urology & Nephrology
John D. Ortiz
Summary: Living with chronic kidney disease requires patients to make difficult lifestyle changes. Support and understanding are crucial for patients to manage the disease effectively.
NATURE REVIEWS NEPHROLOGY
(2022)
Article
Medicine, General & Internal
Felicita Andreotti, Adelaide Iervolino, Eliano Pio Navarese, Aldo Pietro Maggioni, Filippo Crea, Giovanni Scambia
Summary: Acute coronary syndromes (ACS) vary in presentation, mechanisms, outcomes, and treatment responses, with precision medicine aiming to provide personalized interventions. Current precision treatments include immediate coronary revascularization, early coronary angiography, and intensified antithrombotic therapy based on bleeding risk scores. Further stratified analysis of multi-omic datasets is urgently needed for improved diagnosis and treatment of ACS.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nursing
Catherine Brown, Shaouli Shahid, Christina M. Bernardes, Maree Toombs, Paul J. Clark, Elizabeth E. Powell, Patricia C. Valery
Summary: This qualitative study explores the care experiences of Aboriginal and Torres Strait Islander Australians diagnosed with cirrhosis, focusing on the support needed. Thematic analysis identifies six themes, including experiences of diagnosis, prejudices and discrimination from health professionals, health literacy, sources of support, aspects of communication and patient consultation, and the need for psychosocial counseling.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Biotechnology & Applied Microbiology
Brigid K. Grabert, Jennifer Heisler-MacKinnon, Rachel Kurtzman, Adam Bjork, Katelyn Wells, Noel T. Brewer, Melissa B. Gilkey
Summary: Immunization managers in the US are eager to partner with healthcare systems to enhance HPV vaccination rates, but they face barriers such as difficulty in reaching system leadership, differences in organizational cultures, and time constraints. Support and training are needed to facilitate these partnerships and expand program capacity.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Psychology, Multidisciplinary
Joan M. Griffin, Cassie C. Kennedy, Kasey R. Boehmer, Ian G. Hargraves, Hatem Amer, Sheila G. Jowsey-Gregoire
Summary: This study examines the importance of team science in Vascularized Composite Allotransplantation (VCA) teams and highlights the need for careful consideration of team composition, structure, and organizational commitment. It emphasizes the development of processes that foster collaboration for efficient and effective team performance.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Critical Care Medicine
Michael C. C. Reade
Summary: This study discusses eleven priorities for trauma care, including investment in trauma prevention, improving prehospital care, building a high-performance trauma team, applying evidence-based clinical interventions, and enhancing quality assurance. The study emphasizes that continued attention to these priorities can lead to significant reductions in trauma mortality and improve clinical outcomes.
Review
Endocrinology & Metabolism
Sanjay Kalra, Faruque Pathan, Ida Ayu Made Kshanti, Nguyen Quang Bay, Terumasa Nagase, Teresa Oliveria, Shailendra Bajpai
Summary: The correct use of insulin injection technique is crucial for the effectiveness of therapy in diabetes patients. Despite established recommendations and evidence highlighting the importance of effective insulin injection technique, impediments to its use among patients need to be identified, and awareness among patients and healthcare professionals needs to be raised. This review focuses on recent advancements in delivery devices, teaching methods, monitoring, and complication management to optimize injection techniques and improve diabetes outcomes.
Review
Endocrinology & Metabolism
Caroline B. Terwee, Petra J. M. Elders, Marieke T. Blom, Joline W. Beulens, Olaf Rolandsson, Alize A. Rogge, Matthias Rose, Nicola Harman, Paula R. Williamson, Frans Pouwer, Lidwine B. Mokkink, Femke Rutters
Summary: Patient-reported outcomes (PROs) are important for shared decision making and research, but there is a lack of consensus on which PROs and patient-reported outcome measures (PROMs) to use in diabetes. This narrative review provides recommendations for relevant PROs to measure, such as disease-specific symptoms and general symptoms, and suggests the use of generic PROMs supplemented with disease-specific PROMs. However, further validation studies are needed for diabetes-specific PROMs. Standardization and use of psychometrically sound PROMs can improve healthcare for people with diabetes.
Article
Biochemistry & Molecular Biology
Sharon Hausman-Cohen, William LaValley, Heather Way, Emily Gutierrez, Jordan Reeder
Summary: Combining molecular biology and genomics can provide powerful intervention strategies for improving outcomes in children with autism spectrum disorders (ASD). This paper demonstrates how understanding gene function and the effects of genetic variants can be used to develop targeted interventions and highlights the importance of the SHANK3 genomic variant in ASD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Endocrinology & Metabolism
Shahina Pardhan, Tirthalal Upadhyaya, Lee Smith, Tara Sharma, Sarita Tuladhar, Bhojraj Adhikari, John Kidd, Raju Sapkota
Summary: The study aimed to examine the effectiveness of a culturally and linguistically appropriate, patient-centered, target-driven lifestyle intervention with video education training in improving clinical outcomes, health literacy, and diabetic self-care practices in newly diagnosed patients in Nepal. It involved randomly allocating 110 newly diagnosed Type 2 diabetes patients into intervention and control groups, with the intervention group receiving the video education program and customized lifestyle plans. The results showed improvements in clinical outcomes, health literacy, and self-care practices in the intervention group.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Oncology
K. R. Enard, S. E. Nicks, B. A. Campbell, S. M. McClure
Summary: Community-based participatory research (CBPR) is a collaborative partnership approach that emphasizes equity among groups to achieve goals and promote sustainability. This study examines the dynamics of a CBPR-guided partnership aimed at improving cancer outcomes in underserved African American communities, highlighting the benefits and challenges faced in maintaining long-term commitment and building capacity to address disparities.
CANCER CAUSES & CONTROL
(2021)
Article
Endocrinology & Metabolism
David T. Broome, Kevin M. Pantalone, Sangeeta R. Kashyap, Louis H. Philipson
Summary: Maturity-onset diabetes of the young (MODY) is a genetic form of diabetes that remains underdiagnosed. Diagnosis involves clinical presentation, family history, lab, and genetic testing. Treatment and monitoring depend on the identified variant.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Cell Biology
Caitlin L. Maikawa, Andrea d'Aquino, Rayhan A. Lal, Bruce A. Buckingham, Eric A. Appel
Summary: This review discusses the advantages and limitations of recent drug formulation technologies in improving protein stability, pharmacokinetics, prolonging drug delivery, and enabling alternative dosage forms for diabetes management. By providing controlled delivery, these formulations have the potential to enhance closed-loop glycemic control.
SCIENCE TRANSLATIONAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Lesley E. Steinman, Amanda T. Parrish, Marlana J. Kohn, Sherry Wu, KeliAnne K. Hara-Hubbard, Lori Brown, Syed Imam, Barbara Baquero, Peggy A. Hannon, Mark B. Snowden
Summary: By partnering with community-based organizations, a study aims to design more equitable dissemination and implementation strategies to support the adoption of PEARLS.
FRONTIERS IN PUBLIC HEALTH
(2023)