期刊
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
卷 2, 期 11, 页码 407-416出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4251/wjgo.v2.i11.407
关键词
Liver flukes; Viral hepatitis; Liver stem cells; Peribiliary glands; Epidemiology; Extra-hepatic cholangiocarcinoma; Risk factors; Primary sclerosing cholangitis; Intra-hepatic cholangiocarcinoma; Liver cirrhosis
Cholangiocarcinoma (CCA) is a malignant tumour that arises from biliary epithelium at any portion of the biliary tree. CCA is currently classified as intra-hepatic or extra-hepatic CCA (EH-CCA). Recent evidences suggest that intra-hepatic CCA (IH-CCA) and EH-CCA are biologically different cancers, giving further support to a number of recent epidemiological studies showing large differences in terms of incidence, mortality and risk factors. The purpose of this manuscript is to review recent literature dealing with the descriptive epidemiology and risk factors of CCA with a special effort to compare IH-with EH-CCA. (C) 2010 Baishideng. All rights reserved.
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