A review on strontium ranelate long-term antifracture efficacy in the treatment of postmenopausal osteoporosis

Efficacy and Safety of Strontium Ranelate in the Treatment of Osteoporosis in Men

(2013) J.-M. Kaufman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of strontium on proliferation and differentiation of rat bone marrow mesenchymal stem cells

(2012) Yunfeng Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Strontium ranelate treatment increases osteoprotegerin serum levels in postmenopausal osteoporotic women

(2012) J.Y. Reginster et al.   BONE

Implications for Fracture Healing of Current and New Osteoporosis Treatments: An ESCEO Consensus Paper

(2012) J. Goldhahn et al.   CALCIFIED TISSUE INTERNATIONAL

Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)

(2012) C. Cooper et al.   CURRENT MEDICAL RESEARCH AND OPINION

Estrogen and the skeleton

(2012) Sundeep Khosla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: Involvement of osteoprotegerin

(2011) Songlin Peng et al.   BONE

Reduction by strontium of the bone marrow adiposity in mice and repression of the adipogenic commitment of multipotent C3H10T1/2 cells

(2011) C. Fournier et al.   BONE

Adverse Reactions and Drug–Drug Interactions in the Management of Women with Postmenopausal Osteoporosis

(2011) René Rizzoli et al.   CALCIFIED TISSUE INTERNATIONAL

Distribution of strontium and mineralization in iliac bone biopsies from osteoporotic women treated long-term with strontium ranelate

(2011) Audrey Doublier et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption

(2011) Songlin Peng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis

(2011) J-Y. Reginster et al.   OSTEOPOROSIS INTERNATIONAL

Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis

(2011) R. Rizzoli et al.   OSTEOPOROSIS INTERNATIONAL

Strontium ranelate improves implant osseointegration

(2010) Laurent Maïmoun et al.   BONE

Effects of Alendronate and Strontium Ranelate on Cancellous and Cortical Bone Mass in Glucocorticoid-Treated Adult Rats

(2010) P. Sun et al.   CALCIFIED TISSUE INTERNATIONAL

Essential Role of Nuclear Factor of Activated T Cells (NFAT)-mediated Wnt Signaling in Osteoblast Differentiation Induced by Strontium Ranelate

(2010) Olivia Fromigué et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats

(2010) Pierre J. Marie et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study

(2010) Roger MD Zebaze et al.   LANCET

Strontium Ranelate Decreases Receptor Activator of Nuclear Factor- B Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing Receptor

(2010) A. Caudrillier et al.   MOLECULAR PHARMACOLOGY

Strontium ranelate decreases the incidence of new caudal vertebral fractures in a growing mouse model with spontaneous fractures by improving bone microarchitecture

(2010) V. Geoffroy et al.   OSTEOPOROSIS INTERNATIONAL

Positive impact of compliance to strontium ranelate on the risk of nonvertebral osteoporotic fractures

(2010) V. Rabenda et al.   OSTEOPOROSIS INTERNATIONAL

How strontium ranelate, via opposite effects on bone resorption and formation, prevents osteoporosis

(2010) P. J. Marie et al.   OSTEOPOROSIS INTERNATIONAL

Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis

(2010) René Rizzoli et al.   RHEUMATOLOGY INTERNATIONAL

Cost–effectiveness of strontium ranelate for the prevention and treatment of osteoporosis

(2010) Mickaël Hiligsmann et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Cutaneous Side Effects of Antiosteoporosis Treatments

(2010) Philippe Musette et al.   Therapeutic Advances in Musculoskeletal Disease

Long-term treatment of postmenopausal osteoporosis with strontium ranelate: Results at 8 years

(2009) J.Y. Reginster et al.   BONE

Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age

(2009) Ego Seeman et al.   BONE

Osteoblasts play key roles in the mechanisms of action of strontium ranelate

(2009) TC Brennan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intelligent Risk Communication

(2009) Andrzej Czarnecki   DRUG SAFETY

Comparative Effects of Teriparatide and Strontium Ranelate on Bone Biopsies and Biochemical Markers of Bone Turnover in Postmenopausal Women With Osteoporosis*

(2009) Robert R Recker et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mineralization density distribution of postmenopausal osteoporotic bone is restored to normal after long-term alendronate treatment: qBEI and sSAXS data from the fracture intervention trial long-term extension (FLEX)

(2009) P Roschger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Calcium sensing receptor-dependent and receptor-independent activation of osteoblast replication and survival by strontium ranelate

(2009) Olivia Fromigué et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Relationship between 3-month changes in biochemical markers of bone remodelling and changes in bone mineral density and fracture incidence in patients treated with strontium ranelate for 3 years

(2009) O. Bruyère et al.   OSTEOPOROSIS INTERNATIONAL

Influence of remodeling on the mineralization of bone tissue

(2009) G. Boivin et al.   OSTEOPOROSIS INTERNATIONAL

Cost-utility of long-term strontium ranelate treatment for postmenopausal osteoporotic women

(2009) M. Hiligsmann et al.   OSTEOPOROSIS INTERNATIONAL

In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization

(2009) G. Boivin et al.   OSTEOPOROSIS INTERNATIONAL

Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice Research Database

(2009) G. Breart et al.   OSTEOPOROSIS INTERNATIONAL

Systemic treatment with strontium ranelate promotes tibial fracture healing in ovariectomized rats

(2009) Y. F. Li et al.   OSTEOPOROSIS INTERNATIONAL

Treatment of osteoporosis: recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity

(2009) P. Musette et al.   OSTEOPOROSIS INTERNATIONAL

Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis

(2009) P. J. Meunier et al.   OSTEOPOROSIS INTERNATIONAL

Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial

(2008) Jean-Yves Reginster et al.   ARTHRITIS AND RHEUMATISM

Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms

(2008) Joseph Caverzasio   BONE

The Calcium-sensing Receptor Is Involved in Strontium Ranelate-induced Osteoclast Apoptosis

(2008) Anne S. Hurtel-Lemaire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response

(2008) G. J. Atkins et al.   OSTEOPOROSIS INTERNATIONAL

Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants

(2008) S. D. Bain et al.   OSTEOPOROSIS INTERNATIONAL

Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro

(2007) Edith Bonnelye et al.   BONE