NNK-Induced Lung Tumors: A Review of Animal Model

Strain-Specific Spontaneous and NNK-Mediated Tumorigenesis in Pten+/− Mice

(2015) Mary Christine Hollander et al.   NEOPLASIA

A  -tocopherol-rich mixture of tocopherols inhibits chemically induced lung tumorigenesis in A/J mice and xenograft tumor growth

(2010) G. Lu et al.   CARCINOGENESIS

The function of IGF-IR in NNK-mediated lung tumorigenesis

(2010) Megan D. Siwicky et al.   LUNG CANCER

Comparative Functional Genomics Analysis of NNK Tobacco-Carcinogen Induced Lung Adenocarcinoma Development in Gprc5a-Knockout Mice

(2010) Junya Fujimoto et al.   PLoS One

Eukaryotic Initiation Factor 4E Binding Protein Family of Proteins: Sentinels at a Translational Control Checkpoint in Lung Tumor Defense

(2009) Y. Y. Kim et al.   CANCER RESEARCH

β-Carotene promotes the development of NNK-induced small airway-derived lung adenocarcinoma

(2009) Hussein A.N. Al-Wadei et al.   EUROPEAN JOURNAL OF CANCER

Down-Regulation of 14-3-3 Isoforms and Annexin A5 Proteins in Lung Adenocarcinoma Induced by the Tobacco-Specific Nitrosamine NNK in the A/J Mouse Revealed by Proteomic Analysis

(2009) James D. Bortner et al.   JOURNAL OF PROTEOME RESEARCH

Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice

(2009) Maki Igarashi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Effect of gefitinib on N-nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mice

(2009) Daizo Kishino et al.   LUNG CANCER

Fish Oil Supplementation Inhibits NNK-Induced Lung Carcinogenesis in the A/J Mouse

(2009) Heather Mernitz et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Chemopreventive Effect of Kava on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone plus Benzo[a]pyrene-Induced Lung Tumorigenesis in A/J Mice

(2008) T. E. Johnson et al.   Cancer Prevention Research

Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

(2008) Linda E. Sandercock et al.   CARCINOGENESIS

Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

(2008) Stephen Kalscheuer et al.   CARCINOGENESIS

Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice

(2008) Masanao Yokohira et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study

(2008) Hekmat Osman Abdel-Aziz et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY