Prospects for treating osteoarthritis: enzyme–protein interactions regulating matrix metalloproteinase activity

The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer

(2012) Subhankar Chakraborty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Matrix Metalloproteinase Inhibitors: A Review on Bioanalytical Methods, Pharmacokinetics and Metabolism

(2012) Xu Wang et al.   CURRENT DRUG METABOLISM

New Organ-Specific Pharmacological Strategies Interfering With Signaling Pathways In Inflammatory Disorders/Autoimmune Disorders

(2012) Bradley A. Wisler et al.   Current Signal Transduction Therapy

Mammalian Siderophores, Siderophore-binding Lipocalins, and the Labile Iron Pool

(2012) Colin Correnti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Alternate Perspective on the Roles of TIMPs and MMPs in Pathology

(2011) Craig S. Moore et al.   AMERICAN JOURNAL OF PATHOLOGY

Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

(2011) Meina Wang et al.   Annals of the New York Academy of Sciences

Changes in subchondral bone early in the development of osteoarthritis

(2011) S. C. Mastbergen et al.   ARTHRITIS AND RHEUMATISM

Neutrophil gelatinase-associated lipocalin in gastric carcinoma cells and its induction by TPA are controlled by C/EBPβ

(2011) Ze-Peng Du et al.   Biochemistry and Cell Biology

Effects of Hylan G-F 20 supplementation on cartilage preservation detected by magnetic resonance imaging in osteoarthritis of the knee: a two-year single-blind clinical trial

(2011) Yuanyuan Wang et al.   BMC MUSCULOSKELETAL DISORDERS

Lipocalin 2: A multifaceted modulator of human cancer

(2011) Jiang Yang et al.   CELL CYCLE

New Hope for the Treatment of Osteoarthritis Through Selective Inhibition of MMP-13

(2011) N.-G. Li et al.   CURRENT MEDICINAL CHEMISTRY

NGAL is a Precocious Marker of Therapeutic Response

(2011) Valeria Cernaro et al.   CURRENT PHARMACEUTICAL DESIGN

Lipocalin 2 regulation and its complex role in inflammation and cancer

(2011) Chen Li et al.   CYTOKINE

Immunohistochemical detection of a specific receptor for lipocalin2 (solute carrier family 22 member 17, SLC22A17) and its prognostic significance in endometrial carcinoma

(2011) Tsutomu Miyamoto et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Emerging drugs for osteoarthritis

(2011) Gloria L Matthews et al.   EXPERT OPINION ON EMERGING DRUGS

Discovery and Evaluation of a Non-Zn Chelating, Selective Matrix Metalloproteinase 13 (MMP-13) Inhibitor for Potential Intra-articular Treatment of Osteoarthritis

(2011) Christian Gege et al.   JOURNAL OF MEDICINAL CHEMISTRY

Osteoarthritis year 2010 in review: pathomechanisms

(2011) W.B. van den Berg   OSTEOARTHRITIS AND CARTILAGE

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

(2011) Stanley B Cohen et al.   ARTHRITIS RESEARCH & THERAPY

Efficacy of initial methotrexate monotherapy versus combination therapy with a biological agent in early rheumatoid arthritis: a meta-analysis of clinical and radiographic remission

(2010) B. Kuriya et al.   ANNALS OF THE RHEUMATIC DISEASES

New molecular targets for the treatment of osteoarthritis

(2010) Maria José Alcaraz et al.   BIOCHEMICAL PHARMACOLOGY

Molecular Interactions of MMP-13 C-Terminal Domain with Chondrocyte Proteins

(2010) Liang Zhang et al.   CONNECTIVE TISSUE RESEARCH

Disease Modifying Osteoarthritis Drugs: Facing Development Challenges and Choosing Molecular Targets

(2010) Marie-Pierre Hellio Le Graverand-Gastineau   CURRENT DRUG TARGETS

Anticytokine Therapy for Osteoarthritis

(2010) Charles J. Malemud   DRUGS & AGING

Hyaluronic Acid (Supartz®)

(2010) Monique P. Curran   DRUGS & AGING

Induction of Neutrophil Gelatinase-associated Lipocalin Expression by Co-stimulation with Interleukin-17 and Tumor Necrosis Factor-α Is Controlled by IκB-ζ but neither by C/EBP-β nor C/EBP-δ

(2010) Joachim R. Karlsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and biochemical characteristics after intra-articular injection for the treatment of osteoarthritis of the knee: prospective randomized study of sodium hyaluronate and corticosteroid

(2010) Masaki Shimizu et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

The Discovery of Novel Experimental Therapies for Inflammatory Arthritis

(2010) Charles J. Malemud   MEDIATORS OF INFLAMMATION

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis

(2010) Kyoung Soo Kim et al.   RHEUMATOLOGY INTERNATIONAL

Hyaluronic Acid Viscosupplementation and Osteoarthritis

(2009) Eric J. Strauss et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Activation of cartilage matrix metalloproteinases by activated protein C

(2009) Miriam T. Jackson et al.   ARTHRITIS AND RHEUMATISM

Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study

(2009) X. Chevalier et al.   ARTHRITIS AND RHEUMATISM

Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their complex MMP-9/NGAL in breast cancer disease

(2009) Xeni Provatopoulou et al.   BMC CANCER

Targeting Matrix Metalloproteinases in Inflammatory Conditions

(2009) A. Clutterbuck et al.   CURRENT DRUG TARGETS

Targeting JAK/STAT Signaling Pathway in Inflammatory Diseases

(2009) Charles Malemud et al.   Current Signal Transduction Therapy

Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants

(2009) Dorothea Piecha et al.   INFLAMMATION RESEARCH

Neutrophil Gelatinase–Associated Lipocalin (NGAL) as a Marker of Kidney Damage

(2008) Davide Bolignano et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport1

(2008) Rebecca J. Abergel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY