Clonal Heterogeneity Reflected by PI3K-AKT-mTOR Signaling in Human Acute Myeloid Leukemia Cells and Its Association with Adverse Prognosis
出版年份 2018 全文链接
标题
Clonal Heterogeneity Reflected by PI3K-AKT-mTOR Signaling in Human Acute Myeloid Leukemia Cells and Its Association with Adverse Prognosis
作者
关键词
-
出版物
Cancers
Volume 10, Issue 9, Pages 332
出版商
MDPI AG
发表日期
2018-09-17
DOI
10.3390/cancers10090332
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo
- (2018) Yongwei Su et al. BIOCHEMICAL PHARMACOLOGY
- Dueling for dual inhibition: Means to enhance effectiveness of PI3K/Akt/mTOR inhibitors in AML
- (2018) Lauren Herschbein et al. BLOOD REVIEWS
- Human Olfactory Receptors: Novel Cellular Functions Outside of the Nose
- (2018) Désirée Maßberg et al. PHYSIOLOGICAL REVIEWS
- Functional expression of olfactory receptors in human primary melanoma and melanoma metastasis
- (2017) Lian Gelis et al. EXPERIMENTAL DERMATOLOGY
- Therapeutic targeting of leukemic stem cells in acute myeloid leukemia – the biological background for possible strategies
- (2017) Øystein Bruserud et al. Expert Opinion on Drug Discovery
- Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia
- (2017) Yoko Tabe et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The diversified function and potential therapy of ectopic olfactory receptors in non-olfactory tissues
- (2017) Zhe Chen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
- (2016) Hartmut Döhner et al. BLOOD
- The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
- (2016) D. A. Arber et al. BLOOD
- Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy
- (2016) R. Morita et al. CLINICAL CANCER RESEARCH
- Stem and progenitor cells of the mammalian olfactory epithelium: Taking poietic license
- (2016) James E. Schwob et al. JOURNAL OF COMPARATIVE NEUROLOGY
- The Complexity of Targeting PI3K-Akt-mTOR Signalling in Human Acute Myeloid Leukaemia: The Importance of Leukemic Cell Heterogeneity, Neighbouring Mesenchymal Stem Cells and Immunocompetent Cells
- (2016) Annette Brenner et al. MOLECULES
- Genomic Classification and Prognosis in Acute Myeloid Leukemia
- (2016) Elli Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- Deconstructing the molecular architecture of olfactory areas using proteomics
- (2016) Mercedes Lachén-Montes et al. Proteomics Clinical Applications
- Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth
- (2016) Guenhaël Sanz et al. Oncotarget
- Olfactory Receptors in Non-Chemosensory Organs: The Nervous System in Health and Disease
- (2016) Isidro Ferrer et al. Frontiers in Aging Neuroscience
- Monoterpene (−)-citronellal affects hepatocarcinoma cell signaling via an olfactory receptor
- (2015) Désirée Maßberg et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Class I odorant receptors, TAS1R and TAS2R taste receptors, are markers for subpopulations of circulating leukocytes
- (2015) Agne Malki et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Acute Myeloid Leukemia
- (2015) Hartmut Döhner et al. NEW ENGLAND JOURNAL OF MEDICINE
- A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value
- (2014) W.-L. Chen et al. BLOOD
- Promotion of Cancer Cell Invasiveness and Metastasis Emergence Caused by Olfactory Receptor Stimulation
- (2014) Guenhaël Sanz et al. PLoS One
- Antileukaemic effect of PI3K-mTOR inhibitors in acute myeloid leukaemia-gene expression profiles reveal CDC25B expression as determinate of pharmacological effect
- (2013) Håkon Reikvam et al. BRITISH JOURNAL OF HAEMATOLOGY
- Clonal Heterogeneity As Detected by Metaphase Karyotyping Is an Indicator of Poor Prognosis in Acute Myeloid Leukemia
- (2013) Tilmann Bochtler et al. JOURNAL OF CLINICAL ONCOLOGY
- The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia
- (2011) R. Polak et al. BLOOD
- Prognostic impact of discordant results from cytogenetics and flow cytometry in patients with acute myeloid leukemia undergoing hematopoietic cell transplantation
- (2011) Min Fang et al. CANCER
- Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia
- (2011) J Skavland et al. Blood Cancer Journal
- Activation of an Olfactory Receptor Inhibits Proliferation of Prostate Cancer Cells
- (2009) Eva M. Neuhaus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now