MCP-1/CCR2 signaling-mediated astrocytosis is accelerated in a transgenic mouse model of SOD1-mutated familial ALS

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Chemokine CCL2 enhances survival and invasiveness of endometrial stromal cells in an autocrine manner by activating Akt and MAPK/Erk1/2 signal pathway

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Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

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Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

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Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   BRAIN

The Role of Immune and Inflammatory Mechanisms in ALS

(2011) P. A. McCombe et al.   CURRENT MOLECULAR MEDICINE

CCL2/MCP-1 modulation of microglial activation and proliferation

(2011) Ara E Hinojosa et al.   Journal of Neuroinflammation

A predictive model for amyotrophic lateral sclerosis (ALS) diagnosis

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Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

(2011) Thomas Philips et al.   LANCET NEUROLOGY

Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis

(2011) P. Diaz-Amarilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo

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Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice

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Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

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The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

(2010) Grégory Conductier et al.   JOURNAL OF NEUROIMMUNOLOGY

Astrocytes and therapeutics for Parkinson’s disease

(2010) Phillip M. Rappold et al.   Neurotherapeutics

Astrocytes: biology and pathology

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Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis

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Role of Chemokines in CNS Health and Pathology: A Focus on the CCL2/CCR2 and CXCL8/CXCR2 Networks

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Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures

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Immune system alterations in sporadic amyotrophic lateral sclerosis patients suggest an ongoing neuroinflammatory process

(2009) Stefania Mantovani et al.   JOURNAL OF NEUROIMMUNOLOGY

Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1

(2009) Siranush A. Sargsyan et al.   NEUROREPORT

Post-ischemic brain damage: pathophysiology and role of inflammatory mediators

(2008) Diana Amantea et al.   FEBS Journal

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Effects of the PPARγ activator pioglitazone on p38 MAP kinase and IκBα in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis

(2008) Noriyuki Shibata et al.   NEUROPATHOLOGY

Uncovering Genes with Divergent mRNA-Protein Dynamics in Streptomyces coelicolor

(2008) Karthik P. Jayapal et al.   PLoS One

Astrocytes and Ischemic Injury

(2008) T. Takano et al.   STROKE

Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications

(2008) Joseph El Khoury et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Role of astrocytes and chemokine systems in acute TNFα induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-κB and Akt

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