Article
Immunology
Goda Juzenaite, Judith Secklehner, Juho Vuononvirta, Yoseph Helbawi, John B. G. Mackey, Charlotte Dean, James A. Harker, Leo M. Carlin, Sara Rankin, Katia De Filippo
Summary: The study elucidated the rapid response dynamics of neutrophils to Escherichia coli infection, demonstrating their role in capturing pathogens and forming clusters in both the lung and spleen.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Infectious Diseases
Yitao Duan, Shuangqing Liu, Yuting Gao, Peng Zhang, Daqing Mao, Yi Luo
Summary: Macrolides can activate the transcription of the msr(E)-mph(E) operon through the involvement of HNS and CRP. The operon was found to exist widely in diverse species of bacteria, with Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis being the main carriers. These bacteria were primarily isolated from human clinical samples and had a wide geographical distribution.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Physics, Multidisciplinary
Gaspard Junot, Thierry Darnige, Anke Lindner, Vincent A. Martinez, Jochen Arlt, Angela Dawson, Wilson C. K. Poon, Harold Auradou, Eric Clement
Summary: This article investigates the movement and biofilm formation of motile bacteria on surfaces. Using a novel tracking technique, the researchers observed surface residence and escape behaviors. A motility model was proposed to explain the findings and provide new insights into surface trapping efficiency.
PHYSICAL REVIEW LETTERS
(2022)
Article
Multidisciplinary Sciences
Kazuki Kato, Sae Okazaki, Cian Schmitt-Ulms, Kaiyi Jiang, Wenyuan Zhou, Junichiro Ishikawa, Yukari Isayama, Shungo Adachi, Tomohiro Nishizawa, Kira S. Makarova, Eugene V. Koonin, Omar O. Abudayyeh, Jonathan S. Gootenberg, Hiroshi Nishimasu
Summary: The type III-E CRISPR-Cas7-11 effector can catalyze crRNA-guided RNA cleavage by binding crRNA and Csx29, and the binding of tgRNA induces conformational changes in Csx29. Csx29 cleaves Csx30 through a tgRNA-dependent pathway, resulting in the generation of toxic protein fragments and growth arrest, which is regulated by Csx31. Csx30 modulates the cellular response to infection by binding Csx31 and the associated sigma factor RpoE. Additionally, the Cas7-11-Csx29-Csx30 system has been engineered for programmable RNA sensing in mammalian cells.
Article
Infectious Diseases
Pei Yee Woh, May Pui Shan Yeung, William Bernard Goggins
Summary: This study aimed to determine the multiple antibiotic resistance index (MARI) of Salmonella isolated from children hospitalized for gastroenteritis in Hong Kong. The results showed that Salmonella had the highest resistance to ampicillin, ciprofloxacin, and tetracycline, while MDR strains had high resistance towards ampicillin, tetracycline, cotrimoxazole, chloramphenicol, and ciprofloxacin. MARI revealed that 80.2% of Salmonella, including all MDR strains, had indexes greater than 0.2.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2023)
Article
Environmental Sciences
Emily K. Rousham, Muhammad Asaduzzaman, T. I. M. Amin Uddin Mozmader, Mohammed Badrul Amin, Mahdia Rahman, Muhammed Iqbal Hossain, Md Rayhanul Islam, Zahid Hayat Mahmud, Leanne Unicomb, Mohammad Aminul Islam
Summary: The study revealed a high prevalence of ESBL-EC colonization in humans, but it was not significantly associated with poultry exposure. In these community settings, bidirectional transmission of antibiotic resistance between humans, poultry, and the environment is likely to occur, highlighting the importance of One Health mitigation strategies.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2021)
Article
Multidisciplinary Sciences
Theodore A. Chavkin, Loc-Duyen Pham, Aleksandar Kostic
Summary: The study found that oral probiotics EcN can reduce postprandial glycemic response in mice, but not through direct glucose uptake. Further exploration is needed to understand the potential indirect mechanisms of EcN on host glucose metabolism.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Fatma Abdelrahman, Nouran Rezk, Mohamed S. Fayez, Mohamed Abdelmoteleb, Reham Atteya, Mohamed Elhadidy, Ayman El-Shibiny
Summary: This study isolated and characterized three novel bacteriophages against E. coli from sewage water. The phages had a genome size of 44,776 bp and belonged to the Siphoviridae family. They showed good tolerance to a broad range of pH and temperature.
Article
Chemistry, Multidisciplinary
Hanyu Qian, Eric Mclamore, Nikolay Bliznyuk
Summary: Reuse of alternative water sources for irrigation is a sustainable approach to reduce water gaps and increase food production, but it poses a risk of bacterial contamination. This study developed a statistical machine-learning framework to accurately predict the concentration of pathogenic organisms, such as E. coli, in untreated surface water using an impedimetric electrochemical aptasensor. The framework improved prediction accuracy and can be used for rapid decision support in hydroponic irrigation.
Article
Multidisciplinary Sciences
Delia Tomoiaga, Jaclyn Bubnell, Liam Herndon, Paul Feinstein
Summary: Griffith proposed the concept of DNA transfer between bacteria in 1928. Researchers have demonstrated that E. coli can accept multiple plasmids simultaneously, resulting in widespread aclonality during colony development. Tracking clonally related bacteria allows for mosaic analysis of gene function. Additionally, it was discovered that clonally related bacterium rods self-organize fractally and can remain linked during colony growth, presenting a potential target for controlling microbiota growth.
SCIENTIFIC REPORTS
(2022)
Article
Agriculture, Dairy & Animal Science
Jonathan J. Lopez-Islas, Estela T. Mendez-Olvera, Daniel Martinez-Gomez, Andres M. Lopez-Perez, Libertad Orozco, Gerardo Suzan, Carlos Eslava
Summary: Emerging diseases pose a constant challenge in public health, and wild carnivores can be carriers of atypical strains of pathogenic microorganisms, highlighting the importance of natural environments in studying emerging diseases.
Article
Agriculture, Dairy & Animal Science
C. M. Selby, B. D. Graham, L. E. Graham, K. D. Teague, B. M. Hargis, G. Tellez-Isaias, C. N. Vuong
Summary: Avian pathogenic Escherichia coli (E. coli) is a common pathogen introduced to neonatal chicks during hatching, impacting poultry rearing significantly. A seeder challenge model was developed to mimic bacterial bloom effects during hatch, revealing potential methods of controlling bacterial growth in the hatching environment.
Review
Infectious Diseases
Fabio P. Sellera, Luciano C. B. A. Da Silva, Nilton Lincopan
Summary: The COVID-19 pandemic has deepened the relationships between humans and companion animals, leading to an increase in the use of antibiotics and biocides worldwide. Data from global surveillance studies show a linear trend in increasing carbapenem resistance among Gram-negative pathogens in companion animals, with humans potentially acquiring carbapenemase-producing bacteria through contact with infected animals or contaminated environments. The rapid spread of WHO critical priority carbapenemase-producing pathogens in companion animals presents a One Health challenge for the post-pandemic world.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Multidisciplinary Sciences
Habiba Tariq, Zobia Noreen, Aftab Ahmad, Laraib Khan, Mashhood Ali, Muhammad Malik, Aneela Javed, Faisal Rasheed, Alina Fatima, Tanil Kocagoz, Ugur Sezerman, Habib Bokhari
Summary: This study investigated the genetic diversity of pathogenic E. coli strains associated with colorectal cancer (CRC). It found that 43.47% of the cancer-associated isolates belonged to phylogroup B2, showed resistance to multiple antibiotics, and exhibited cytotoxic activity that may contribute to the progression of CRC.
Article
Multidisciplinary Sciences
Ahmed R. Elbestawy, Hany F. Ellakany, Hatem S. Abd El-Hamid, Madiha S. Ibrahim, Ahmed R. Gado, Nagwa S. Mustafa, Ihab M. Moussa, Khalid S. Al-Maary, Dalia S. Al-Sarar, Hanan O. Alshammari, Turki M. Dawoud, Hassan A. Hemeg, Hussein M. Galal
Summary: This study evaluated the cross-protection ability of live attenuated E. coli vaccine against heterologous APEC serotypes, showing significant protection but subtle differences in clinical signs, post-mortem lesions, mortality rates, E. coli re-isolation, histopathological examination, final body weight, and feed conversion ratio.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Roland D. Kersten, Amy L. Lane, Markus Nett, Taylor K. S. Richter, Brendan M. Duggan, Pieter C. Dorrestein, Bradley S. Moore
Article
Microbiology
Taylor K. S. Richter, Chambers C. Hughes, Bradley S. Moore
ENVIRONMENTAL MICROBIOLOGY
(2015)
Article
Multidisciplinary Sciences
Federico M. Lauro, Emiley A. Eloe-Fadrosh, Taylor K. S. Richter, Nicola Vitulo, Steven Ferriera, Justin H. Johnson, Douglas H. Bartlett
Article
Microbiology
Taylor K. S. Richter, Tracy H. Hazen, Diana Lam, Christian L. Coles, Jessica C. Seidman, Yaqi You, Ellen K. Silbergeld, Claire M. Fraser, David A. Rasko
Article
Infectious Diseases
Rodrigo T. Hernandes, Tracy H. Hazen, Luis F. dos Santos, Taylor K. S. Richter, Jane M. Michalski, David A. Rasko
PLOS NEGLECTED TROPICAL DISEASES
(2020)
Article
Genetics & Heredity
Susan R. Leonard, Ivan Simko, Mark K. Mammel, Taylor K. S. Richter, Maria T. Brandl
Summary: Processed MAP lettuce microbiome changes during storage, with temperature and harvest season affecting EcO157 survival and microbiome composition. Temperature abuse can promote EcO157 multiplication, while cold storage supports EcO157 survival and influences microbiome composition. The seasonality of STEC outbreaks associated with lettuce in California may be linked to the physiology and microbiomes of fall- and spring-harvested lettuce.
ENVIRONMENTAL MICROBIOME
(2021)
Article
Biotechnology & Applied Microbiology
Maria T. Brandl, Mark K. Mammel, Ivan Simko, Taylor K. S. Richter, Solomon T. Gebru, Susan R. Leonard
Summary: This study characterized the microbial communities of lettuce phyllosphere and surface soil at harvest in California. It was found that harvest season and field type significantly influenced the microbiome composition of leaves and soil. The composition of these microbiomes was also correlated with specific weather factors. Additionally, the interactions between fungi and bacteria on lettuce leaves varied between seasons.
Article
Microbiology
F. M. Lauro, T. K. Stratton, R. A. Chastain, S. Ferriera, J. Johnson, S. M. D. Goldberg, A. A. Vayanos, D. H. Bartlett
GENOME ANNOUNCEMENTS
(2013)