Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

A Melanoma Lymph Node Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: A Second Case of Leucocyte-Tumor Cell Hybridization in Cancer Metastasis

(2017) Greggory S. LaBerge et al.   PLoS One

"Stealth dissemination" of macrophage-tumor cell fusions cultured from blood of patients with pancreatic ductal adenocarcinoma

(2017) Gary A. Clawson et al.   PLoS One

Fusion between cancer cells and macrophages occurs in a murine model of spontaneous neu+ breast cancer without increasing its metastatic potential

(2016) Michela Lizier et al.   Oncotarget

Analysis of circulating CD14+/CD16+ monocyte-derived macrophages (MDMs) in the peripheral blood of patients with oral squamous cell carcinoma

(2016) Martin Grimm et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

GOplot: an R package for visually combining expression data with functional analysis: Fig. 1.

(2015) Wencke Walter et al.   BIOINFORMATICS

Macrophage traits in cancer cells are induced by macrophage-cancer cell fusion and cannot be explained by cellular interaction

(2015) Ivan Shabo et al.   BMC CANCER

Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness

(2015) Jianguo Xue et al.   BMC CANCER

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Tissue Regeneration in the Chronically Inflamed Tumor Environment: Implications for Cell Fusion Driven Tumor Progression and Therapy Resistant Tumor Hybrid Cells

(2015) Thomas Dittmar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transmission of Information in Neoplasia by Extracellular Vesicles

(2015) Aurelio Lorico et al.   Biomed Research International

Co-inhibition of colony stimulating factor-1 receptor and BRAF oncogene in mouse models of BRAFV600E melanoma

(2015) Shin Foong Ngiow et al.   OncoImmunology

Abstract A26: Integrated epigenomic profiling reveals widespread demethylation in melanoma, and reveals aberrant CSF-1 receptor expression as a regulator of malignant growth and invasion inhibited by PLX3397

(2014) Yongkai Mo et al.   CANCER RESEARCH

Colony-stimulating factor 1 potentiates lung cancer bone metastasis

(2014) Jaclyn Y Hung et al.   LABORATORY INVESTIGATION

Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells

(2014) A Patsialou et al.   ONCOGENE

EMT and Acquisition of Stem Cell-Like Properties Are Involved in Spontaneous Formation of Tumorigenic Hybrids between Lung Cancer and Bone Marrow-Derived Mesenchymal Stem Cells

(2014) Mei-Hua Xu et al.   PLoS One

Circulating giant macrophages as a potential biomarker of solid tumors

(2014) Daniel L. Adams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling inputs to invadopodia and podosomes

(2013) D. Hoshino et al.   JOURNAL OF CELL SCIENCE

Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip

(2013) Weian Sheng et al.   LAB ON A CHIP

Fusion between Hematopoietic and Epithelial Cells in Adult Human Intestine

(2013) Alain D. Silk et al.   PLoS One

A Melanoma Brain Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: First Evidence for Fusion in Human Cancer

(2013) Rossitza Lazova et al.   PLoS One

Spontaneous Formation of Tumorigenic Hybrids between Breast Cancer and Multipotent Stromal Cells Is a Source of Tumor Heterogeneity

(2012) Germana Rappa et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

(2012) J. B. Mitchem et al.   CANCER RESEARCH

Circulating Tumor Cells in Melanoma Patients

(2012) Gary A. Clawson et al.   PLoS One

Fabrication and Use of MicroEnvironment microArrays (MEArrays)

(2012) Chun-Han Lin et al.   Jove-Journal of Visualized Experiments

Fusion between Intestinal Epithelial Cells and Macrophages in a Cancer Context Results in Nuclear Reprogramming

(2011) Anne E. Powell et al.   CANCER RESEARCH

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Cell Fusion as a Hidden Force in Tumor Progression

(2009) X. Lu et al.   CANCER RESEARCH

Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time

(2009) Ivan Shabo et al.   INTERNATIONAL JOURNAL OF CANCER

Inflammation and Proliferation Act Together to Mediate Intestinal Cell Fusion

(2009) Paige S. Davies et al.   PLoS One

TGFβ in Cancer

(2008) Joan Massagué   CELL

Cell Fusion Theory: Can It Explain What Triggers Metastasis?

(2008) Andrea Carter   JNCI-Journal of the National Cancer Institute