Article
Genetics & Heredity
Mike Dyall-Smith, Friedhelm Pfeiffer, Pei-Wen Chiang, Sen-Lin Tang
Summary: Hardycor1 virus, isolated in 1998 infecting Halorubrum coriense, has a large genome with low similarity to known viruses. The virus stock also contains two induced proviruses of the host.
Article
Chemistry, Applied
Alejandra Aragon-Leon, Lorena Moreno-Vilet, Marisela Gonzalez-Avila, Pedro Martin Mondragon-Cortez, Guilherme Lanzi Sassaki, Raul Balam Martinez-Perez, Rosa Maria Camacho-Ruiz
Summary: This study evaluated the production, chemical characterization, biological and technological properties of inulin biosynthesized by a halophilic archaeon. The inulin showed high production, emulsifying index, and prebiotic capacity.
CARBOHYDRATE POLYMERS
(2023)
Article
Microbiology
Ana Sofia Vazquez-Madrigal, Alejandra Barbachano-Torres, Melchor Arellano-Plaza, Manuel Reinhart Kirchmayr, Ilaria Finore, Annarita Poli, Barbara Nicolaus, Susana De la Torre Zavala, Rosa Maria Camacho-Ruiz
Summary: This study identified seventeen halophilic archaea from the Santa Barbara saltern in Sonora, Mexico, belonging to Haloarcula, Halolamina, and Halorubrum genera. The presence of neutral lipids and different phospholipids in these strains was confirmed. Carotenoid production in response to glucose, succinic acid, and glutamic acid varied among the strains, with Halorubrum sp. M5 showing negative effects from certain carbon sources. This work highlights the diversity in growth and carotenoid production of haloarchaea under different carbon sources.
Article
Genetics & Heredity
Runting Ding, Na Yang, Jianguo Liu
Summary: This study reports the osmoadaptive mechanism of an extremely halophilic archaea, H. kocurii 2020YC7, isolated from a high salt environment. The strain utilizes various strategies including K+ uptake and output, trehalose production, and glycine betaine uptake to adapt to high salt conditions. Glycine betaine acts as the primary osmotic solute at high salt concentrations, while trehalose functions as an osmotic solute at lower salt concentrations.
Article
Chemistry, Multidisciplinary
Yueqiang Xu, Yan Li, Xin You, Caixia Pei, Zhuo Wang, Siming Jiao, Xin Zhao, Xuan Lin, Yang Lu, Cheng Jin, George Fu Gao, Jianjun Li, Qi Wang, Yuguang Du
Summary: This study found that exopolysaccharides produced by the halophilic archaeon Haloarcula hispanica ATCC33960 can inhibit the binding of SARS-CoV-2 to host cells, providing a novel antiviral mechanism and a guide for designing new drugs.
FRONTIERS IN CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Saghar Shahbazi, Mohsen Zargar, Mohammad Reza Zolfaghari, Mohammad Ali Amoozegar
Summary: Carotenoids extracted from native Iranian halophilic microorganisms have been found to possess anticancer properties, particularly bacterioruberin from strain A15, which demonstrated significant cytotoxicity against breast cancer cells.
CELL BIOCHEMISTRY AND FUNCTION
(2023)
Article
Microbiology
Fatma Karray, Manel Ben Abdallah, Nidhal Baccar, Hatem Zaghden, Sami Sayadi
Summary: This study identified Halorubrum, Natrinema, and Haloarcula genera as promising candidates for PHB production using soluble starch as a carbon source under high salinity conditions. Three PHB-producing strains, related to Halorubrum chaoviator, Natrinema pallidum, and Haloarcula tradensis, were found to be the most efficient, reaching values of 9.25%, 7.11%, and 1.42% of cell dry weight, respectively.
ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL
(2021)
Article
Chemistry, Applied
Maryam Siroosi, Farshad Borjian Borujeni, Mohammad Ali Amoozegar, Hamid Babavalian, Mehdi Hassanshahian
Summary: The study focused on the production and partial purification of amylase from a halophilic archaeon, identifying optimal conditions for enzyme production and activity. A strain of Haloarcula sp. D61 was found to produce amylase under stress conditions with 23% salts, with peak production at 3-4 M NaCl, 40-45°C, and pH 7.0. Different carbon sources affected amylase production, with maltose inducing production while lactose, sucrose, and glucose repressed it.
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Athmika, Sudeep D. Ghate, A. B. Arun, Sneha S. Rao, S. T. Arun Kumar, Mrudula Kinarulla Kandiyil, Kanekar Saptami, P. D. Rekha
Summary: The Halomonas malpeensis strain YU-PRIM-29(T) is a halophilic bacterium that produces yellow pigment, exopolysaccharide (EPS), and industrially important metabolites such as zeaxanthin pigment, ectoine, and polyhydroxyalkanoate (PHA). Genome analysis revealed genes involved in EPS biosynthesis and other important metabolic pathways. The EPS showed strong emulsifying activities against petroleum hydrocarbons and its production was influenced by the carbon source.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Paula Mondragon, Sungmin Hwang, Amy Schmid, Julie A. Maupin-Furlow
Summary: Studying haloarchaea helps us understand how extremophiles survive and respond to harsh environments. A common strategy is to mutate genes identified through omics studies and compare the mutant strains with wildtype strains to study stress response mechanisms. However, current methods to study recovery from extreme stress have limitations. In this study, a method was developed to overcome these limitations and successfully evaluate the function of genes during hypochlorite stress in the halophilic archaeon Haloferax volcanii.
Article
Biochemistry & Molecular Biology
Bhakti B. Salgaonkar, Judith M. Braganca
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2015)
Article
Biotechnology & Applied Microbiology
Kabilan Mani, Sivaraman Chandrasekaran, Bhakti B. Salgaonkar, Srikanth Mutnuri, Judith M. Braganca
ANNALS OF MICROBIOLOGY
(2015)
Article
Environmental Sciences
Deepthi Das, Bhakti B. Salgaonkar, Kabilan Mani, Judith M. Braganca
Article
Biochemistry & Molecular Biology
Bhakti B. Salgaonkar, Kabilan Mani, Judith Maria Braganca
Article
Biotechnology & Applied Microbiology
B. B. Salgaonkar, K. Mani, J. M. Braganca
JOURNAL OF APPLIED MICROBIOLOGY
(2013)
Article
Biotechnology & Applied Microbiology
B. B. Salgaonkar, M. Kabilan, J. M. Braganca
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2011)
Article
Biotechnology & Applied Microbiology
Vidhya Prabhudessai, Bhakti Salgaonkar, Judith Braganca, Srikanth Mutnuri
BIOMED RESEARCH INTERNATIONAL
(2014)
Article
Biotechnology & Applied Microbiology
Bhakti B. Salgaonkar, Kabilan Mani, Anjana Nair, Sowmya Gangadharan, Judith M. Braganca
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2012)