Metabolism and Bioenergetics in the Right Ventricle and Pulmonary Vasculature in Pulmonary Hypertension

Lung18F-Fluorodeoxyglucose Positron Emission Tomography for Diagnosis and Monitoring of Pulmonary Arterial Hypertension

(2012) Glenn Marsboom et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension

(2012) Glenn Marsboom et al.   CIRCULATION RESEARCH

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

(2012) Jalees Rehman et al.   FASEB JOURNAL

The spectrum of pyruvate dehydrogenase complex deficiency: Clinical, biochemical and genetic features in 371 patients

(2012) Kavi P. Patel et al.   MOLECULAR GENETICS AND METABOLISM

Outcomes of hospitalisation for right heart failure in pulmonary arterial hypertension

(2011) A. Campo et al.   EUROPEAN RESPIRATORY JOURNAL

Sensitive cardiac troponin I predicts poor outcomes in pulmonary arterial hypertension

(2011) G.A. Heresi et al.   EUROPEAN RESPIRATORY JOURNAL

Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle’s cycle

(2011) Yong-Hu Fang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Progressive Right Ventricular Dysfunction in Patients With Pulmonary Arterial Hypertension Responding to Therapy

(2011) Mariëlle C. van de Veerdonk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hypoxia Inducible-Factor1α Regulates the Metabolic Shift of Pulmonary Hypertensive Endothelial Cells

(2010) Iwona Fijalkowska et al.   AMERICAN JOURNAL OF PATHOLOGY

Long-term Effects of Epoprostenol on the Pulmonary Vasculature in Idiopathic Pulmonary Arterial Hypertension

(2010) Stuart Rich et al.   CHEST

Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension

(2010) Stephen L. Archer et al.   CIRCULATION

The von Hippel–Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice

(2010) Michele M. Hickey et al.   JOURNAL OF CLINICAL INVESTIGATION

Right and Left Ventricular Myocardial Perfusion Reserves Correlate with Right Ventricular Function and Pulmonary Hemodynamics in Patients with Pulmonary Arterial Hypertension

(2010) Jens Vogel-Claussen et al.   RADIOLOGY

Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension

(2010) G. Sutendra et al.   Science Translational Medicine

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure

(2009) Harm J. Bogaard et al.   CIRCULATION

Prognostic factors of acute heart failure in patients with pulmonary arterial hypertension

(2009) B. Sztrymf et al.   EUROPEAN RESPIRATORY JOURNAL

Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22α-targeted overexpression of the serotonin transporter

(2009) Christophe Guignabert et al.   FASEB JOURNAL

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

(2009) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Efficacy of Ranolazine in Patients With Chronic Angina

(2009) Sean R. Wilson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Clinical Classification of Pulmonary Hypertension

(2009) Gérald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

(2008) E D Michelakis et al.   BRITISH JOURNAL OF CANCER

Trimetazidine, a Metabolic Modulator, Has Cardiac and Extracardiac Benefits in Idiopathic Dilated Cardiomyopathy

(2008) Helena Tuunanen et al.   CIRCULATION

Right ventricular contractility in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension

(2008) M. J. Overbeek et al.   EUROPEAN RESPIRATORY JOURNAL

Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells

(2008) Michael J. Hitchler et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

(2007) Stephen L. Archer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY