Article
Environmental Sciences
Shubhayu Saha, Ambarish Vaidyanathan, Fiona Lo, Claudia Brown, Jeremy J. Hess
Summary: The study found that the seasonal distribution of pollen types and their impact on health varied across different MSAs. All pollen types were associated with an increased relative risk of allergic rhinitis visits, while only tree and weed pollen were associated with an increased risk of medication fills. Controlling for air pollution and ILI did not significantly impact the effect estimates.
ENVIRONMENTAL HEALTH
(2021)
Article
Allergy
Sheryl A. van Nunen, Melanie B. Burk, Pamela K. Burton, Geoffrey Ford, Richard J. Harvey, Alexander Lozynsky, Elizabeth Pickford, Janet S. Rimmer, Joanne Smart, Michael F. Sutherland, Francis Thien, Heinrich C. Weber, Harry Zehnwirth, Ed Newbigin, Constance H. Katelaris
Summary: This study aimed to evaluate the treatment effectiveness of 300 IR 5-grass SLIT in SAR patients in the southern hemisphere, and to investigate the impact of polysensitization to subtropical grass pollens on treatment responses. The results demonstrated significant improvements in SAR symptoms in both monosensitized and polysensitized patients, with sustained improvements over multiple pollen seasons.
WORLD ALLERGY ORGANIZATION JOURNAL
(2022)
Article
Allergy
Georgia Papapostolou, Hampus Kiotseridis, Kerstin Romberg, Aslog Dahl, Leif Bjermer, Magnus Lindgren, David Aronsson, Alf Tunsater, Ellen Tufvesson
Summary: The study found that cognitive function was impaired in grass pollen-allergic children during the pollen season, particularly in spatial working memory. The more severe the symptoms, the longer the reaction time in cognitive tests, and the quality of life was also impaired compared to non-allergic children. No differences were found in stress or inflammatory biomarkers between the groups.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Maira Bonini, Gianna Serafina Monti, Matteo Maria Pelagatti, Valentina Ceriotti, Elisabetta Elena Re, Barbara Brame, Paolo Bottero, Anna Tosi, Adriano Vaghi, Alberto Martelli, Giovanni Maria Traina, Loredana Rivolta, Federica Rivolta, Claudio Maria Ortolani
Summary: In this study, the correlation between ragweed pollen concentration and symptom severity in patients allergic to ragweed pollen was investigated. The effectiveness of ragweed allergen immunotherapy was also assessed. The results showed a significant correlation between pollen load and symptom intensity, and patients treated with immunotherapy had significantly reduced symptom levels.
SCIENTIFIC REPORTS
(2022)
Article
Allergy
Jo A. Douglass, Caroline Lodge, Samantha Chan, Alice Doherty, Ju Ann Tan, Celina Jin, Alastair Stewart, Anne M. Southcott, Andrew Gillman, Joy Lee, Danny Csutoros, Liam Hannan, Laurence Ruane, Sara Barnes, Lou Irving, Nur-Shirin Harun, Phillipe Lachapelle, Kymble Spriggs, Michael Sutherland, Katharine See, Christine F. McDonald, Matthew Conron, Naghmeh Radhakrishna, Christopher Worsnop, Fay H. Johnston, Janet M. Davies, Vanessa Bryant, Linda Iles, David Ranson, Paresa Spanos, Don Vicendese, Adrian Lowe, Edward J. Newbigin, Philip Bardin, Shyamali Dharmage
Summary: This study found that low FEV1 value, high Asthma Control Questionnaire score, and elevated levels of RGP-sp IgE concentration, eosinophil counts, and fractional exhaled nitric oxide were associated with the risk of thunderstorm asthma among individuals with seasonal allergic rhinitis.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Alexander Kurganskiy, Simon Creer, Natasha de Vere, Gareth W. Griffith, Nicholas J. Osborne, Benedict W. Wheeler, Rachel N. Mclnnes, Yolanda Clewlow, Adam Barber, Georgina L. Brennan, Helen M. Hanlon, Matthew Hegarty, Caitlin Potter, Francis Rowney, Beverley Adams-Groom, Geoff M. Petch, Catherine H. Pashley, Jack Satchwell, Letty A. de Weger, Karen Rasmussen, Gilles Oliver, Charlotte Sindt, Nicolas Bruffaerts, Carsten A. Skjoth
Summary: It is challenging to manage symptoms of allergic rhinitis caused by immune overreaction to allergens. A new study proposes statistical and mechanistic models to forecast the severity of the grass pollen season, suggesting that climate change may increase severity by up to 60%. These models can guide individuals and healthcare professionals in preparing for the grass pollen season.
Article
Environmental Sciences
Michiel Stas, Raf Aerts, Marijke Hendrickx, Andy Delcloo, Nicolas Dendoncker, Sebastien Dujardin, Catherine Linard, Tim Nawrot, An Van Nieuwenhuyse, Jean-Marie Aerts, Jos Van Orshoven, Ben Somers
Summary: The study on individuals sensitized to Betulaceae pollen showed that exposure to green space with lower density of allergenic trees on case days can reduce the severity of pollen allergy symptoms, while air pollutants contribute to more severe allergy symptoms.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Nutrition & Dietetics
Joseph Yusin, Vivian Wang, Susanne M. Henning, Jieping Yang, Chi-Hong Tseng, Gail Thames, Irina Arnold, David Heber, Ru-Po Lee, Laura Sanavio, Yajing Pan, Tianyu Qin, Zhaoping Li
Summary: Combining nasal corticosteroid with broccoli sprout extract led to the most significant improvement in peak nasal inspiratory flow and total nasal symptoms scores in patients diagnosed with grass-induced allergic rhinitis.
Article
Environmental Sciences
Janet M. Davies, Beth Addison Smith, Andelija Milic, Bradley Campbell, Shanice Van Haeften, Pamela Burton, Benedict Keaney, Edwin R. Lampugnani, Don Vicendese, Danielle Medek, Alfredo Huete, Bircan Erbas, Edward Newbigin, Constance H. Katelaris, Simon G. Haberle, Paul J. Beggs
Summary: This study monitored grass and other pollen concentrations in four cities in eastern Australia and found that the complexity of grass pollen seasons is influenced by latitude. The magnitude of the grass pollen season is correlated with pasture greenness, rainfall, and the number of hot days within the season.
ENVIRONMENTAL RESEARCH
(2022)
Article
Allergy
Yuan Zhang, Lin Xi, Yunbo Gao, Yanran Huang, Feifei Cao, Wei Xiong, Chengshuo Wang, Luo Zhang
Summary: The study found that preseasonal omalizumab therapy could significantly reduce nasal symptoms and improve quality of life in seasonal allergic rhinitis patients, with less medication usage compared to standard pharmacotherapy.
CLINICAL AND TRANSLATIONAL ALLERGY
(2022)
Article
Allergy
Conny Hoeflich, Galina Balakirski, Zuzanna Hajdu, Jens Malte Baron, Katharina Fietkau, Hans F. Merk, Ulrich Strassen, Henning Bier, Wolfgang Dott, Hans-Guido Muecke, Wolfgang Straff, Gerda Wurpts, Amir S. Yazdi, Adam Chaker, Stefani T. M. Roeseler
Summary: The study showed varying sensitization rates to both common and non-frequent pollen allergens in adult patients from two German federal states. Sensitization to non-frequent pollen allergens needs to be considered for patients with seasonal symptoms, and availability of test allergens for these less common allergies is important for patient management. Data on sensitization correlated partly with each other and with symptom periods, showing a seasonal pattern similar to pollen data.
CLINICAL AND TRANSLATIONAL ALLERGY
(2021)
Article
Biochemistry & Molecular Biology
Shoko Ueda, Jun Ito, Norihiro Harada, Sonoko Harada, Hitoshi Sasano, Yuuki Sandhu, Yuki Tanabe, Sumiko Abe, Satomi Shiota, Yuzo Kodama, Tetsutaro Nagaoka, Fumihiko Makino, Asako Chiba, Hisaya Akiba, Ryo Atsuta, Sachiko Miyake, Kazuhisa Takahashi
Summary: This study investigated the efficacy of sublingual immunotherapy (SLIT) in asthmatic patients with seasonal allergic rhinitis (SAR-JCP) and found that SLIT not only significantly improved allergic rhinitis and asthma symptoms, but also improved airway resistance. Moreover, the reduction in peripheral blood gamma delta T cells after SLIT was associated with the improvement of asthma symptoms.
Article
Allergy
Nicholas J. Campion, Sergio Villazala-Merino, Ryan S. Thwaites, Victoria Stanek, Helen Killick, Eleftheria Pertsinidou, Mohammed Zghaebi, Josef Toth, Renate Froschl, Thomas Perkmann, Katharina Gangl, Sven Schneider, Robin Ristl, Ian C. Scott, Emma Suzanne Cohen, Magnus Molin, Margit Focke-Tejkl, Guenther Regelsberger, Trevor T. Hansel, Rudolf Valenta, Verena Niederberger-Leppin, Julia Eckl-Dorna
Summary: This study aimed to characterize the immunologic and clinical nasal responses to birch pollen allergen challenge, with a special focus on the late allergic response.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Integrative & Complementary Medicine
Lukas Israel, Gabriele Rotter, Ulrike Foerster-Ruhrmann, Josef Hummelsberger, Rainer Noegel, Andreas Michalsen, Tatjana Tissen-Diabate, Sylvia Binting, Thomas Reinhold, Miriam Ortiz, Benno Brinkhaus
Summary: Self-administered acupressure as a self-care technique shows potential benefits for patients with seasonal allergic rhinitis, improving disease-specific quality of life and reducing disease-related symptoms and medication intake. High-quality confirmatory studies are needed for further validation of these findings, including a sham-control group.
Article
Otorhinolaryngology
Jiayi Yang, Weidong Wang, Zhen Shen, Wei Kang, Pengfei Zhang, Xin Chen, Huajing Li, Yuan Shao, Lifeng Liu, Shaoqiang Zhang, Fang Quan
Summary: This study investigates the efficacy and safety of sublingual immunotherapy (SLIT) with A. annua allergens in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. The results show that the symptoms and medication scores of the SLIT group decreased in 2021 and remained lower than the baseline in 2022. Compared with the SLIT group, the control group showed significant improvement in efficacy indexes in 2022. Therefore, A. annua-SLIT can safely and effectively treat patients with moderate-severe seasonal allergic rhinoconjunctivitis over two pollen seasons.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)