Genome-Wide Expression Quantitative Trait Loci Analysis Using Mixed Models

CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis

(2018) Nishanthi Thalayasingam et al.   Arthritis & Rheumatology

PancanQTL: systematic identification of cis-eQTLs and trans-eQTLs in 33 cancer types

(2017) Jing Gong et al.   NUCLEIC ACIDS RESEARCH

An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci

(2017) Jin Hyun Ju et al.   PLoS Computational Biology

MTG2: an efficient algorithm for multivariate linear mixed model analysis based on genomic information: Table 1.

(2016) S. H. Lee et al.   BIOINFORMATICS

Analytical Models For Genetics of Human Traits Influenced By Sex

(2016) Chaeyoung Lee   CURRENT GENOMICS

Best Linear Unbiased Prediction of Individual Polygenic Susceptibility to Sporadic Vascular Dementia

(2016) Chaeyoung Lee   JOURNAL OF ALZHEIMERS DISEASE

RNA splicing is a primary link between genetic variation and disease

(2016) Yang I. Li et al.   SCIENCE

Epistasis and covariance: how gene interaction translates into genomic relationship

(2016) Johannes W. R. Martini et al.   THEORETICAL AND APPLIED GENETICS

Age- and gender-dependent heterogeneous proportion of variation explained by SNPs in quantitative traits reflecting human health

(2015) Dain Lee et al.   AGE

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

(2015) Fabian Grubert et al.   CELL

CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

(2015) Zhonghui Tang et al.   CELL

Statistical power for identifying nucleotide markers associated with quantitative traits in genome-wide association analysis using a mixed model

(2015) Jimin Shin et al.   GENOMICS

A mixed model reduces spurious genetic associations produced by population stratification in genome-wide association studies

(2015) Jimin Shin et al.   GENOMICS

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(2015) Anne-Sophie Jannot et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Joint analysis of SNP and gene expression data in genetic association studies of complex diseases

(2014) Yen-Tsung Huang et al.   Annals of Applied Statistics

Genome-wide eQTLs and heritability for gene expression traits in unrelated individuals

(2014) Shengjie Yang et al.   BMC GENOMICS

Advantages and pitfalls in the application of mixed-model association methods

(2014) Jian Yang et al.   NATURE GENETICS

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Mixed Model Methods for Genomic Prediction and Variance Component Estimation of Additive and Dominance Effects Using SNP Markers

(2014) Yang Da et al.   PLoS One

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

(2014) Tamara T. Koopmann et al.   PLoS One

Impact of regulatory variation from RNA to protein

(2014) A. Battle et al.   SCIENCE

Further Improvements to Linear Mixed Models for Genome-Wide Association Studies

(2014) Christian Widmer et al.   Scientific Reports

Underestimation of heritability using a mixed model with a polygenic covariance structure in a genome-wide association study for complex traits

(2013) Hyunju Ryoo et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Effectively Identifying eQTLs from Multiple Tissues by Combining Mixed Model and Meta-analytic Approaches

(2013) Jae Hoon Sul et al.   PLoS Genetics

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

eQTL Epistasis – Challenges and Computational Approaches

(2013) Yang Huang et al.   Frontiers in Genetics

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

(2012) S.H. Lee et al.   BIOINFORMATICS

Targeted maximum likelihood estimation for marginal time-dependent treatment effects under density misspecification

(2012) Mireille E. Schnitzer et al.   BIOSTATISTICS

DNase I sensitivity QTLs are a major determinant of human expression variation

(2012) Jacob F. Degner et al.   NATURE

Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies

(2012) Nicoló Fusi et al.   PLoS Computational Biology

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mixed linear model approach adapted for genome-wide association studies

(2010) Zhiwu Zhang et al.   NATURE GENETICS

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Genomic prediction of simulated multibreed and purebred performance using observed fifty thousand single nucleotide polymorphism genotypes1

(2009) K. Kizilkaya et al.   JOURNAL OF ANIMAL SCIENCE

Estimation of significance thresholds for genomewide association scans

(2008) Frank Dudbridge et al.   GENETIC EPIDEMIOLOGY

Accurate Discovery of Expression Quantitative Trait Loci Under Confounding From Spurious and Genuine Regulatory Hotspots

(2008) H. M. Kang et al.   GENETICS

Bayesian LASSO for Quantitative Trait Loci Mapping

(2008) Nengjun Yi et al.   GENETICS

Extinction risk depends strongly on factors contributing to stochasticity

(2008) Brett A. Melbourne et al.   NATURE

Predicting Unobserved Phenotypes for Complex Traits from Whole-Genome SNP Data

(2008) Sang Hong Lee et al.   PLoS Genetics