期刊
CANCER MANAGEMENT AND RESEARCH
卷 6, 期 -, 页码 171-180出版社
DOVE MEDICAL PRESS LTD
DOI: 10.2147/CMAR.S57846
关键词
glioblastoma; colorectal cancer; tissue stem cell marker
类别
The concept of cancer stem cells has gained considerable interest in the last few decades, partly because of their potential implication in therapy resistance. However, the lack of specific cellular surface markers for these cells has impeded their isolation, making the characterization of this cellular subpopulation technically challenging. Recent studies have indicated that leucine-rich repeat-containing G-protein-coupled receptor 4 and 5 (LGR4 and LGR5) expression in multiple organs may represent a global marker of adult stem cells. This review aims to give an overview of LGR4 and LGR5 as cancer stem cell markers and their function in development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据