Synergy Between Proline-Rich Antimicrobial Peptides and Small Molecule Antibiotics Against Selected Gram-Negative Pathogens in vitro and in vivo

Proline-rich antimicrobial peptides show a long-lasting post-antibiotic effect on Enterobacteriaceae and Pseudomonas aeruginosa

(2017) Luzia Holfeld et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Immunomodulatory effects of anti-microbial peptides

(2016) Laszlo Otvos Jr.   ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA

Membrane interactions of proline-rich antimicrobial peptide, Chex1-Arg20, multimers

(2016) Wenyi Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pharmacokinetics andin vivoefficacy of optimized oncocin derivatives

(2016) Rico Schmidt et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Discovery and Function of a General Core Hormetic Stress Response in E. coli Induced by Sublethal Concentrations of Antibiotics

(2016) Aurélie Mathieu et al.   Cell Reports

Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance

(2015) Johann D. D. Pitout et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin, mechanisms and prevalence of resistance

(2015) Abed Zahedi Bialvaei et al.   CURRENT MEDICAL RESEARCH AND OPINION

Therapeutic utility of antibacterial peptides in wound healing

(2015) Laszlo Otvos et al.   Expert Review of Anti-Infective Therapy

Heat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseases

(2015) Sandro Dattilo et al.   Immunity & Ageing

Combinations of β-Lactam or Aminoglycoside Antibiotics with Plectasin Are Synergistic against Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus

(2015) Yanmin Hu et al.   PLoS One

In VitroandIn VivoActivities of Antimicrobial Peptides Developed Using an Amino Acid-Based Activity Prediction Method

(2014) Xiaozhe Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Designer Proline-rich Antibacterial Peptide A3-APO Prevents Bacillus anthracis Mortality by Deactivating Bacterial Toxins

(2014) Laszlo Otvos et al.   PROTEIN AND PEPTIDE LETTERS

Rapid systemic and local treatments with the antibacterial peptide dimer A3-APO and its monomeric metabolite eliminate bacteria and reduce inflammation in intradermal lesions infected with Propionibacterium acnes and meticillin-resistant Staphylococcus aureus

(2013) Eszter Ostorhazi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK

(2013) Michael Zahn et al.   JOURNAL OF MOLECULAR BIOLOGY

Immune modulation by multifaceted cationic host defense (antimicrobial) peptides

(2013) Ashley L Hilchie et al.   Nature Chemical Biology

Therapeutic antimicrobial peptides may compromise natural immunity

(2012) M. G. J. L. Habets et al.   Biology Letters

Novel approach to predicting hormetic effects of antibiotic mixtures on Vibrio fischeri

(2012) Xiaoming Zou et al.   CHEMOSPHERE

Oncocin derivative Onc72 is highly active against Escherichia coli in a systemic septicaemia infection mouse model

(2012) D. Knappe et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antimicrobial Peptides: Multifunctional Drugs for Different Applications

(2012) Lars-Ove Brandenburg et al.   Polymers

Efficacy of a leptin receptor antagonist peptide in a mouse model of triple-negative breast cancer

(2011) Laszlo Otvos et al.   EUROPEAN JOURNAL OF CANCER

Broad-spectrum antimicrobial efficacy of peptide A3-APO in mouse models of multidrug-resistant wound and lung infections cannot be explained by in vitro activity against the pathogens involved

(2011) Eszter Ostorhazi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A

(2011) A. Cruz-Migoni et al.   SCIENCE

Intramuscularly administered peptide A3-APO is effective against carbapenem-resistant Acinetobacter baumannii in mouse models of systemic infections

(2010) Eszter Ostorhazi et al.   BIOPOLYMERS

Emergence of a colistin-resistant KPC-2-producing Klebsiella pneumoniae ST258 clone in Hungary

(2010) Á. Tóth et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Synergy among antibacterial peptides and between peptides and small-molecule antibiotics

(2010) Marco Cassone et al.   Expert Review of Anti-Infective Therapy

Preclinical advantages of intramuscularly administered peptide A3-APO over existing therapies in Acinetobacter baumannii wound infections

(2010) E. Ostorhazi et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment

(2010) Anastasia Nijnik et al.   JOURNAL OF IMMUNOLOGY

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

(2010) Christopher G. Evans et al.   JOURNAL OF MEDICINAL CHEMISTRY

The designer proline-rich antibacterial peptide A3-APO is effective against systemic Escherichia coli infections in different mouse models

(2009) Dora Szabo et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Hormesis and medicine

(2008) Edward J. Calabrese   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Protective effects of the combination of α-helical antimicrobial peptides and rifampicin in three rat models of Pseudomonas aeruginosa infection

(2008) Oscar Cirioni et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Scope and limitations of the designer proline-rich antibacterial peptide dimer, A3-APO, alone or in synergy with conventional antibiotics

(2008) Marco Cassone et al.   PEPTIDES