Stress-related and homeostatic cytokines regulate Vγ9Vδ2 T-cell surveillance of mevalonate metabolism

γδT Cells: First Line of Defense and Beyond

(2014) Yueh-hsiu Chien et al.   Annual Review of Immunology

The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells

(2014) Andrew Sandstrom et al.   IMMUNITY

Human    Thymocytes Are Functionally Immature and Differentiate into Cytotoxic Type 1 Effector T Cells upon IL-2/IL-15 Signaling

(2014) J. C. Ribot et al.   JOURNAL OF IMMUNOLOGY

Successful adoptive transfer and in vivo expansion of haploidentical γδ T cells

(2014) Martin Wilhelm et al.   Journal of Translational Medicine

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

(2014) Christopher J Chan et al.   NATURE IMMUNOLOGY

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

Regulation of mevalonate metabolism in cancer and immune cells

(2013) Martin Thurnher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The impact of response on bone-directed therapy in patients with multiple myeloma

(2013) A. Larocca et al.   BLOOD

Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage

(2013) A. Cohnen et al.   BLOOD

Innate Immune Receptors: Key Regulators of Metabolic Disease Progression

(2013) Chengcheng Jin et al.   Cell Metabolism

Essential Requirements of Zoledronate-Induced Cytokine and    T Cell Proliferative Responses

(2013) O. Nussbaumer et al.   JOURNAL OF IMMUNOLOGY

Butyrophilin 3A1 Plays an Essential Role in Prenyl Pyrophosphate Stimulation of Human V 2V 2 T Cells

(2013) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

(2013) Stefano Vavassori et al.   NATURE IMMUNOLOGY

Immunogenic and Antioxidant Effects of a Pathogen-Associated Prenyl Pyrophosphate in Anopheles gambiae

(2013) Bo G. Lindberg et al.   PLoS One

Regulation of Development of CD56brightCD11c+ NK-like Cells with Helper Function by IL-18

(2013) Wen Li et al.   PLoS One

Inhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells

(2013) Chiara Riganti et al.   OncoImmunology

 9 and  2CDR3 domains regulate functional avidity of T cells harboring  9 2TCRs

(2012) C. Grunder et al.   BLOOD

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human    T-cell subset

(2012) C. Harly et al.   BLOOD

Zoledronic acid-induced expansion of γδ T cells from early-stage breast cancer patients: effect of IL-18 on helper NK cells

(2012) Tomoharu Sugie et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

(2012) Wolfgang Kastenmüller et al.   CELL

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

(2012) William A. Freed-Pastor et al.   CELL

Homeostatic maintenance of T cells and natural killer cells

(2012) Onur Boyman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Novel Aspects of Mevalonate Pathway Inhibitors as Antitumor Agents

(2012) M. Thurnher et al.   CLINICAL CANCER RESEARCH

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Harnessing γδ T cells in anticancer immunotherapy

(2012) Dalil Hannani et al.   TRENDS IN IMMUNOLOGY

Defining the human T helper 17 cell phenotype

(2012) Francesco Annunziato et al.   TRENDS IN IMMUNOLOGY

DC-like cell-dependent activation of human natural killer cells by the bisphosphonate zoledronic acid is regulated by    T lymphocytes

(2011) O. Nussbaumer et al.   BLOOD

ThePafoncogene is essential for hematopoietic stem cell function and development

(2011) Yacine M. Amrani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune Modulation by Zoledronic Acid in Human Myeloma: An Advantageous Cross-Talk between V 9V 2 T Cells,    CD8+ T Cells, Regulatory T Cells, and Dendritic Cells

(2011) B. Castella et al.   JOURNAL OF IMMUNOLOGY

Involvement of CD56brightCD11c+ Cells in IL-18-Mediated Expansion of Human    T Cells

(2011) J. Tsuda et al.   JOURNAL OF IMMUNOLOGY

Discovery of IL-18 As a Novel Secreted Protein Contributing to Doxorubicin Resistance by Comparative Secretome Analysis of MCF-7 and MCF-7/Dox

(2011) Ling Yao et al.   PLoS One

IL-2 Costimulation Enables Statin-Mediated Activation of Human NK Cells, Preferentially through a Mechanism Involving CD56+ Dendritic Cells

(2010) G. Gruenbacher et al.   CANCER RESEARCH

Targeting    T Lymphocytes for Cancer Immunotherapy: From Novel Mechanistic Insight to Clinical Application

(2010) A. Q. Gomes et al.   CANCER RESEARCH

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Cell Density Plays a Critical Role in Ex Vivo Expansion of T Cells for Adoptive Immunotherapy

(2010) Qiangzhong Ma et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Partial and Ineffective Activation of V 9V 2 T Cells by Mycobacterium tuberculosis-Infected Dendritic Cells

(2010) S. Meraviglia et al.   JOURNAL OF IMMUNOLOGY

Effect of IL-18 on Expansion of γδ T Cells Stimulated by Zoledronate and IL-2

(2010) Wen Li et al.   JOURNAL OF IMMUNOTHERAPY

Dysregulation of the mevalonate pathway promotes transformation

(2010) J. W. Clendening et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD56+ human blood dendritic cells effectively promote TH1-type    T-cell responses

(2009) G. Gruenbacher et al.   BLOOD

γδ T Cells and the Lymphoid Stress-Surveillance Response

(2009) Adrian C. Hayday   IMMUNITY

Highly Active Microbial Phosphoantigen Induces Rapid yet Sustained MEK/Erk- and PI-3K/Akt-Mediated Signal Transduction in Anti-Tumor Human γδ T-Cells

(2009) Daniel V. Correia et al.   PLoS One

Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

(2008) Anke J. Roelofs et al.   BRITISH JOURNAL OF HAEMATOLOGY

Isopentenyl Pyrophosphate-Activated CD56+    T Lymphocytes Display Potent Antitumor Activity toward Human Squamous Cell Carcinoma

(2008) A. A.Z. Alexander et al.   CLINICAL CANCER RESEARCH