期刊
ONCOIMMUNOLOGY
卷 2, 期 4, 页码 -出版社
LANDES BIOSCIENCE
DOI: 10.4161/onci.23433
关键词
head and neck squamous cell carcinoma; personalized medicine; phage display; tumor-associated antigens
Antibody signatures may become sophisticated screening tools for early diagnosis and the development of personalized anticancer treatments. We used biopanning to enrich the immune response of head and neck squamous cell carcinoma (HNSCC) patients. This method revealed a HNSCC-specific antibody signature and allowed for the discovery of a novel oncogene, L23.
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